Research & Clinical Trials
Clinical trial programs at The Angeles Clinic and Research Institute offer people with cancer a chance to get the best care while helping to make improvements in the care available for future patients. Participating in oncology clinical trials continues the chain of giving initiated by prior patients with cancer and helps oncologists answer many questions that remain unanswered in cancer therapy. With the help of patients participating in cancer clinical trials, we will achieve our goal of effectively treating and ultimately curing cancer.
Recently, the identification of predictive oncology biomarkers in common carcinomas has led to significant progress in personalized therapy, higher response rates, and clinical benefit. These genes, genetic mutations, proteins and signaling pathways have produced paradigm shifting targeted therapies with clear survival benefit. The results from clinical trials utilizing these therapies have resulted in FDA approval of these groundbreaking therapies as standard in oncologic care. By interrogating individual tumors we can block genes that ultimately have led to the cancer
Progress in effectively blocking the Braf mutation has produced clear survival benefit in metastatic melanoma and the approval of Vemurafenib in August. With the identification of other genetic mutations in this system, the use of multiple drug targets in this tumor system may lead to additive increase in survival. Conversely, in patients not harboring the Braf mutation, identification and targeting of genes like nras can lead to long-term clinical benefits
The Angeles Clinic and Research Institute has established an international reputation for developing new cancer therapies, providing the best in experimental and traditional treatments, and expertly guiding and training the next generation of clinicians. We are committed to bringing innovative therapeutic options to all of our patients with cancer. As part of this commitment, our cancer clinical trials program has been expanded to include Experimental Therapeutics (Phase I) and Drug Development programs. With this commitment strengthened, we can continue to make advances in cancer care.
Through our oncology clinical trials program, The Angeles Clinic and Research Institute continues our ongoing commitment to offer our patients with cancer excellence in research and patient care. We offer multiple cancer clinical trials in a wide range of cancerous tumors. On behalf of The Angeles Clinic and Research Institute, we thank you for considering these important therapeutic options and look forward to helping you.
More Information About Clinical Trials
Melanoma & Skin Cancer
The Melanoma Center at The Angeles Clinic and Research Institute brings together patients and expert physicians in a clinical program that offers state-of-the-art treatments along with access to the latest investigational agents. An elite center of academic research, the Melanoma Center is internationally recognized as a premier center for the comprehensive treatment for all stages of melanoma. Our physicians excel in providing patients with individualized recommendations for therapy most appropriate for their condition and stage of disease.
Patients at the Melanoma Center at The Angeles Clinic and Research Institute benefit from the center’s affiliation with world-class surgical oncologists, internationally recognized as leaders in their field. The Melanoma Center’s collaborative efforts also encompass paradigm-shifting therapies in radiation oncology such as Gamma knife and Cyberknife technology. Coupled with a dedication to continued clinical trial research, these services allow truly comprehensive therapies for every patient.
According to statistics released by the American Cancer Society approximately 68,720 new cases of the disease were diagnosed in 2009 with 8,650 estimated deaths. At the Melanoma Center at the Angeles Clinic and Research Institute, we work diligently to reduce these numbers.
Melanoma Center Director Omid Hamid, MD heads a multidisciplinary team dedicated to ensuring unsurpassed care to each patient. With a disease that has few established therapeutic options, clinical trials offer the possibility of further therapy and response. Coupled with the extended options
The Angeles Clinic and Research Institute offers a multitude of trials utilizing the newest therapeutic options in the adjuvant and metastatic setting including:
- Immunologic therapy
- Novel cell cycle targeted therapeutics
- Anti-angiogenic therapy
- Localized therapy such as intrarterial linfusion
Call (310) 231-2185 or use our secure online appointment request form to schedule an appointment at The Angeles Clinic and Research Institute Melanoma & Skin Cancer Center in West Los Angeles.
Melanoma & Skin Cancer
Experience is crucial when dealing with a rare aggressive cancer like melanoma. The Melanoma Center at The Angeles Clinic and Research Institute brings patients and expert physicians together in a clinical program offering state-of-the-art treatments along with access to the latest investigational agents. An elite center of academic research, the Melanoma Center at The Angeles Clinic and Research Institute is internationally recognized as a premier center for the comprehensive treatment of all stages of cancer. Our physicians excel in guiding patients with individualized recommendations for therapy most appropriate for their condition and stage of disease.
Skin Cancers
Skin cancer is the most common form of cancer in the United States. There are many types of skin cancers. They are classified as melanomas or non-melanomas. Melanomas begin in the melanocytes, the cells in skin that produce color. Melanoma can spread quickly to other parts of the body. It is the deadliest form of skin cancer. Non-melanomas originate in skin cells other than melanocytes. Non-melanomas are less aggressive and rarely spread.
Exposure to the ultraviolet (UV) rays in the sun and a history of childhood sunburns are the main causes of most skin cancers. In some cases, skin cancer may be prevented. Skin cancer that is detected and treated early is very curable. It is important to have regular skin and mole checks by a skin specialist. Untreated skin cancer can cause disfigurement, spread to other parts of the body, and cause death. Learn more about skin cancer.
Melanoma
Melanoma is the deadliest form of skin cancer. It occurs when the melanocytes in the skin grow abnormally and out of control. Exposure to ultraviolet (UV) rays from the sun and a history of childhood sunburns contribute to the development of melanoma. Researchers are finding that some people may inherit genes that lead to melanoma formation.
Melanomas that are small, shallow, detected early, and treated early have very good cure rates. Untreated melanomas are very aggressive and fast growing. This cancer can quickly spread throughout the body resulting in life-threatening complications and death. Our board-certified, fellowship-trained oncologists utilize state-of-the-art treatments for aggressive, cutaneous, ocular, mucosal melanomas. Learn more about melanoma.
Learn more about melanoma clinical trials at The Angeles Clinic and Research Institute.
Call (310) 231-2185 or use our secure online appointment request form to schedule an appointment at The Angeles Clinic and Research Institute Melanoma & Skin Cancer Center in West Los Angeles.
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