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Faculty Publications May 30-June 6


A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published May 30-June 6. 


Sustainability of the Subspecialty of Anesthesiology Critical Care: An Expert Consensus and Review of the Literature. Flynn, Brigid C., Megan H. Hicks, Craig S. Jabaley, Shawn Simmons, Courtney Maxey-Jones, Vivek Moitra, Dan Brown, Ashish K. Khanna, Brent Kidd, Jarva Chow, Shweta Yemul Golhar, Kaveh Hemati, Talia K. Ben-Jacob, Margit Kaufman, Miguel Cobas, Michael Nurok, George Williams, and Mark E. Nunnally. Journal of Cardiothoracic and Vascular Anesthesia, April, S1053-0770(24)00267-2.

Moving Forward With Normothermic Regional Perfusion Amidst Ethical Controversy. Batten, Jason N., Michael Nurok, Miriam P. Cotler, Bradley L. Adams, Richard Hasz, Kristopher P. Croome, Jordan Hoffman, and Anji Wall. The American Journal of Bioethics: AJOB 24 (6): 41–43.

Biomedical Sciences

How Much Online Pornography Is Too Much? A Comparison of Two Theoretically Distinct Assessment Scales. Vera Cruz, Germano, Elias Aboujaoude, Magdalena Liberacka-Dwojak, Monika Wi?ko??-D?bczy?ska, Lucien Rochat, Riaz Khan, and Yasser Khazaal. Archives of Public Health = Archives Belges De Sante Publique 82 (1): 79.

Coronary Artery Wall Contrast Enhancement Imaging Impact on Disease Activity Assessment in IgG4-RD a Direct Marker of Coronary Involvement. Du, Yaqi, Shuang Ding, Ce Li, Yun Bai, Xinrui Wang, Debiao Li, Yibin Xie, Guoguang Fan, Lianming Wu, and Guan Wang. Journal of Cardiovascular Magnetic Resonance, May, 101047.

Microglia Undergo Sex-Dimorphic Transcriptional and Metabolic Rewiring During Aging. Kang, Seokjo, Emily Y. Ko, Amelia E. Andrews, Juliana E. Shin, Karina J. Nance, Pijus K. Barman, Peter S. Heeger, Willard M. Freeman, Bérénice A. Benayoun, and Helen S. Goodridge. Journal of Neuroinflammation 21 (1): 150.


Editorial: Facing the Dual Challenges of TAVR With Concomitant Mitral Stenosis: Double, Double, Toil and Trouble. Chakravarty, Tarun, Moody Makar, and Hasan Jilaihawi. Cardiovascular Revascularization Medicine: Including Molecular Interventions, May, S1553-8389(24)00509-8.

Editorial Echocardiography for ‘Incremental Value of Myocardial Global Longitudinal Strain in Predicting Major Adverse Cardiac Events Among Patients With Hypertrophic Cardiomyopathy’ By Zhuang H. and Colleagues. Park, Jakob, and Florian Rader. Echocardiography (Mount Kisco, N.Y.) 41 (6): e15855.

Differentiation Between Descending Thoracic Aortic Diseases Using Machine Learning and Plasma Proteomic Signatures. Momenzadeh, Amanda, Simion Kreimer, Dongchuan Guo, Matthew Ayres, Daniel Berman, Kuang-Yuh Chyu, Prediman K. Shah, Dianna Milewicz, Ali Azizzadeh, Jesse G. Meyer, and Sarah Parker. Clinical Proteomics 21 (1): 38.

In Vivo Safety and Pulmonary Vein Isolation Performance of a New Cryoballoon for the Treatment of Atrial Fibrillation. Bai, Rong, Yu Liao, Xunzhang Wang, Kevin Rosenthal, Justin Vessey, Meital Mazor, and Wilber Su. Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing, June.

Advancing Transthyretin Amyloidosis Drug Development in an Evolving Treatment Landscape: Amyloidosis Forum Meeting Proceedings. Maurer, Mathew S., Prem Soman, Adrian Hernandez, Pablo Garcia-Pavia, James Signorovitch, L. J. Wei, Mazen Hanna, Frederick L. Ruberg, Michelle Kittleson, Dhruv Kazi, Sharmila Dorbala, Kristen Hsu, Isabelle Lousada, Rosalyn Adigun, Preston Dunnmon, Jeffery Kelly, Julian Gillmore, and Amyloidosis Forum Meeting Panelists. Advances in Therapy, June.

Society for Healthcare Epidemiology of America Position Statement on Pandemic Preparedness for Policymakers: Mitigating Supply Shortages. Weber, David Jay, Anurag N. Malani, Erica S. Shenoy, David B. Banach, Lynne Jones Batshon, Westyn Branch-Elliman, Ghinwa Dumyati, Sarah Haessler, Vincent P. Hsu, Robin L. P. Jump, Trini A. Mathew, Rekha K. Murthy, and Steven A. Pergam. Infection Control and Hospital Epidemiology, June, 1–5.

Computational Biomedicine

PFERM: A Fair Empirical Risk Minimization Approach With Prior Knowledge. Hou, Bojian, Andrés Mondragón, Davoud Ataee Tarzanagh, Zhuoping Zhou, Andrew J. Saykin, Jason H. Moore, Marylyn D. Ritchie, Qi Long, and Li Shen. AMIA Joint Summits on Translational Science Proceedings. AMIA Joint Summits on Translational Science 2024: 211–20.

KRAGEN: A Knowledge Graph-Enhanced RAG Framework for Biomedical Problem Solving Using Large Language Models. Matsumoto, Nicholas, Jay Moran, Hyunjun Choi, Miguel E. Hernandez, Mythreye Venkatesan, Paul Wang, and Jason H. Moore. Bioinformatics (Oxford, England), June, btae353.


De Quervain’s Tenosynovitis: As Seen From the Perspective of the Patient. Parikh, Harin B., Mackinzie A. Stanley, Cassie C. Tseng, Haben Berihun, and Stuart H. Kuschner. Journal of Hand Surgery Global Online 6 (3): 328–32.

Shared Decision-Making for Lung Cancer Screening: More Straw for the Camel’s Back. Green, Jonas B. The American Journal of Managed Care 30 (6 Spec No.): SP428–29.

High Frequency of Germline Variants in CFTR Identified in PDAC Patients Enrolled in an Expanded Panel Multi-Gene Panel Testing Program. Hendifar, Andrew, Megan Hitchins, Marie Lauzon, Kathryn E. Hatchell, Brandie Heald, Stephen Pandol, Anjaparavanda P. Naren, and Arsen Osipov. HPB, May, S1365-182X(24)01721-0.

Microbial Aromatic Amino Acid Metabolism Is Modifiable in Fermented Food Matrices to Promote Bioactivity. Kasperek, Mikaela C., Adriana Velasquez Galeas, Maria Elisa Caetano-Silva, Zifan Xie, Alexander Ulanov, Michael La Frano, Suzanne Devkota, Michael J. Miller, and Jacob M. Allen. Food Chemistry 454 (May): 139798.

Early Trajectories of Virological and Immunological Biomarkers and Clinical Outcomes in Patients Admitted to Hospital for COVID-19: An International, Prospective Cohort Study. Jensen, Tomas O., Thomas A. Murray, Greg A. Grandits, Mamta K. Jain, Birgit Grund, Kathryn Shaw-Saliba, Michael A. Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V. Baker, Peter Chen, Robin L. Dewar, Anna L. Goodman, Timothy J. Hatlen, Helene C. Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G. Leshnower, David Looney, Charalampos D. Moschopoulos, Henry Mugerwa, Daniel D. Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M. Tauseef Rehman, Adam Rupert, Randy Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R. Ko, and ACTIV-3/TICO Study Group. The Lancet. Microbe, May, S2666-5247(24)00015-6.

Appropriateness of ChatGPT in Answering Heart Failure Related Questions. King, Ryan C., Jamil S. Samaan, Yee Hui Yeo, Behram Mody, Dawn M. Lombardo, and Roxana Ghashghaei. Heart, Lung & Circulation, May, S1443-9506(24)00165-3.

Eruptive Melanocytic Nevi in the Setting of Encorafenib, Cetuximab, and Binimetinib Combination Therapy: A Case Report. Lam, Karen, Gregory A. Gates, Daniel Q. Bach, and Kyle Cheng. Case Reports in Dermatology 16 (1): 133–39.

Revascularization in Left Ventricular Systolic Dysfunction: A Meta-Analysis of Kaplan-Meier Reconstructed Individual Patient Data. Lee, Grace, Abdullah Malik, Dominique Vervoort, Derrick Y. Tam, Guillaume Marquis-Gravel, Björn Redfors, Mario Gaudino, and Stephen E. Fremes. The Canadian Journal of Cardiology, May, S0828-282X(24)00414-8.

2023 EULAR Classification Criteria for Hand Osteoarthritis. Haugen, Ida K., David T. Felson, Abhishek Abhishek, Francis Berenbaum, Sita Bierma-Zeinstra, Krysia S. Dziedzic, John James Edwards, Martin Englund, Merete Hermann-Eriksen, Gabriel Herrero-Beaumont, Catherine Hill, Mariko L. Ishimori, Helgi Jonsson, Teemu Karjalainen, Ying Ying Leung, Emmanuel Maheu, Christian D. Mallen, Michelle Marshall, Rikke H. Moe, Roberta Ramonda, Valentin Ritschl, Marco Jpf Ritt, Tanja A. Stamm, Zoltan Szekanecz, Florus van der Giesen, Lotte A. van de Stadt, Coen van der Meulen, Ruth Wittoek, Elsie Greibrokk, Hellen Laheij, and Margreet Kloppenburg. Annals of the Rheumatic Diseases, May, ard-2023-225073.

Plasma sFlt-1/PlGF Ratio of 11.5 Multiples of Median Predicts Preeclampsia With Severe Features Within Two Weeks of Testing. Espinoza, Jimmy, Vinicius F. Calsavara, Sarah Kilpatrick, Sarosh Rana, Maged M. Costantine, Kim Boggess, Blair J. Wylie, Tiffany A. Moore Simas, Judette M. Louis, Stephanie L. Gaw, Amy Murtha, Samantha Wiegand, Yvonne Gollin, Deepjot Singh, Robert M. Silver, Danielle E. Durie, Britta Panda, Errol R. Norwitz, Irina Burd, Beth Plunkett, Rachel K. Scott, Elizabeth Lemoine, Ravi Thadhani, and S. Ananth Karumanchi. American Journal of Obstetrics and Gynecology, May, S0002-9378(24)00659-8.

Ascites Is a Poor Prognostic Factor in Advanced Pancreatic Adenocarcinoma and May Be Undertreated: A Prospective Cohort Study. Wang, Justin, Yujie Cui, Arsen Osipov, Jun Gong, Stephen Pandol, Simon Lo, Nicholas Nissen, Anser Abbas, Abrahm Levi, and Andrew Hendifar. Clinical and Translational Gastroenterology, June.

Impact of the Early COVID-19 Pandemic on Incidence and Outcomes of Hepatocellular Carcinoma in the United States. Liang, Jeff, Yi-Te Lee, Yee Hui Yeo, Michael Luu, Walid Ayoub, Alexander Kuo, Hirsh Trivedi, Aarshi Vipani, Srinivas Gaddam, Hyunseok Kim, Yun Wang, Nicole Rich, Kambiz Kosari, Nicholas Nissen, Neehar Parikh, Amit G. Singal, and Ju Dong Yang. Clinical and Translational Gastroenterology, June.

Cell-Free DNA for the Detection of Kidney Allograft Rejection. Aubert, Olivier, Cindy Ursule-Dufait, Romain Brousse, Juliette Gueguen, Maud Racapé, Marc Raynaud, Elisabet Van Loon, Angelica Pagliazzi, Edmund Huang, Stanley C. Jordan, Kenneth D. Chavin, Gaurav Gupta, Dhiren Kumar, Tarek Alhamad, Sanjiv Anand, Jorge Sanchez-Garcia, Basmah A. Abdalla, Julien Hogan, Rouba Garro, Darshana M. Dadhania, Pranjal Jain, Didier A. Mandelbrot, Maarten Naesens, Raja Dandamudi, Vikas R. Dharnidharka, Dany Anglicheau, Carmen Lefaucheur, and Alexandre Loupy. Nature Medicine, June.

Global Epidemiology of Alcohol-Associated Liver Disease in Adolescents and Young Adults. Danpanichkul, Pojsakorn, Vincent L. Chen, Primrose Tothanarungroj, Apichat Kaewdech, Yatawee Kanjanakot, Panisara Fangsaard, Phuuwadith Wattanachayakul, Kwanjit Duangsonk, Siwanart Kongarin, Ju Dong Yang, Robert J. Wong, Mazen Noureddin, Luis Antonio Díaz, Juan Pablo Arab, Suthat Liangpunsakul, and Karn Wijarnpreecha. Alimentary Pharmacology & Therapeutics, June.

Standards of Care for Medical Management of Acromegaly in Pituitary Tumor Centers of Excellence (PTCOE). Giustina, Andrea, M. M. Uygur, S. Frara, A. Barkan, N. R. Biermasz, P. Chanson, P. Freda, M. Gadelha, L. Haberbosch, U. B. Kaiser, S. Lamberts, E. Laws, L. B. Nachtigall, V. Popovic, M. Reincke, A. J. van der Lely, J. a. H. Wass, S. Melmed, and F. F. Casanueva. Pituitary, June.

SHEA Position Statement on Pandemic Preparedness for Policymakers: Building a Strong and Resilient Healthcare Workforce. Banach, David B., Trini A. Mathew, Lynne Jones Batshon, Westyn Branch-Elliman, Ghinwa Dumyati, Sarah Haessler, Vincent P. Hsu, Robin L. P. Jump, Anurag N. Malani, Rekha K. Murthy, Steven A. Pergam, Erica S. Shenoy, and David J. Weber. Infection Control and Hospital Epidemiology, June, 1–4.

SHEA Position Statement on Pandemic Preparedness for Policymakers: Introduction and Overview. Hsu, Vincent P., Sarah Haessler, David B. Banach, Lynne Jones Batshon, Westyn Branch-Elliman, Ghinwa Dumyati, Robin L. P. Jump, Anurag N. Malani, Trini A. Mathew, Rekha K. Murthy, Steven A. Pergam, Erica S. Shenoy, and David J. Weber. Infection Control and Hospital Epidemiology, June, 1–3.

SHEA Position Statement on Pandemic Preparedness for Policymakers: Pandemic Data Collection, Maintenance, and Release. Branch-Elliman, Westyn, David B. Banach, Lynne J. Batshon, Ghinwa Dumyati, Sarah Haessler, Vincent P. Hsu, Robin L. P. Jump, Anurag N. Malani, Trini A. Mathew, Rekha K. Murthy, Steven A. Pergam, Erica S. Shenoy, and David J. Weber. Infection Control and Hospital Epidemiology, June, 1–5..

Society for Healthcare Epidemiology of America Position Statement on Pandemic Preparedness for Policymakers: Mitigating Supply Shortages. Weber, David Jay, Anurag N. Malani, Erica S. Shenoy, David B. Banach, Lynne Jones Batshon, Westyn Branch-Elliman, Ghinwa Dumyati, Sarah Haessler, Vincent P. Hsu, Robin L. P. Jump, Trini A. Mathew, Rekha K. Murthy, and Steven A. Pergam. Infection Control and Hospital Epidemiology, June, 1–5.


Contribution of New and Chronic Cortical Lesions to Disability Accrual in Multiple Sclerosis. Beck, Erin S., W. Andrew Mullins, Jonadab Dos Santos Silva, Stefano Filippini, Prasanna Parvathaneni, Josefina Maranzano, Mark Morrison, Daniel J. Suto, Corinne Donnay, Henry Dieckhaus, Nicholas J. Luciano, Kanika Sharma, María Ines Gaitán, Jiaen Liu, Jacco A. de Zwart, Peter van Gelderen, Irene Cortese, Sridar Narayanan, Jeff H. Duyn, Govind Nair, Pascal Sati, and Daniel S. Reich. Brain Communications 6 (3): fcae158.

Association of Loneliness With Functional Connectivity MRI, Amyloid-? PET, and Tau PET Neuroimaging Markers of Vulnerability for Alzheimer’s Disease. Zhao, Amanda, Laura J. Balcer, Jayandra J. Himali, Adrienne O’Donnell, Yashar Rahimpour, Charles DeCarli, Mitzi M. Gonzales, Hugo J. Aparicio, Jaime Ramos-Cejudo, Rachel Kenney, Alexa Beiser, Sudha Seshadri, and Joel Salinas. Journal of Alzheimer’s Disease: JAD, May.


‘Women’s Work’: Gender and the Physician Workforce. Temkin, Sarah M., Arghavan Salles, Elizabeth Barr, Cecilia B. Leggett, Jeffrey S. Reznick, and Melissa S. Wong. Social Science & Medicine (1982) 351 Suppl 1 (June): 116556.

The Benefit of Active Management in True Knot of the Umbilical Cord: A Retrospective Study. Weissbach, Tal, Shir Lev, Yonatan Back, Abeer Massarwa, Raanan Meyer, Tal Elkan Miller, Alina Weissmann-Brenner, Boaz Weisz, Shali Mazaki-Tovi, and Eran Kassif. Archives of Gynecology and Obstetrics, June.

Unmet Financial Needs Among Patients Crowdfunding to Support Gynecologic Cancer Care. O’Connor, Reed M., Dandi S. Huang, B. J. Rimel, Kenneth H. Kim, Andrew J. Li, Kristin N. Taylor, and Margaret I. Liang. Gynecologic Oncology 186 (June): 199–203.

TRIM71 Mutations Cause a Neurodevelopmental Syndrome Featuring Ventriculomegaly and Hydrocephalus. Duy, Phan Q., Bettina Jux, Shujuan Zhao, Kedous Y. Mekbib, Evan Dennis, Weilai Dong, Carol Nelson-Williams, Neel H. Mehta, John P. Shohfi, Jane Juusola, Garrett Allington, Hannah Smith, Sandrine Marlin, Kahina Belhous, Berrin Monteleone, G. Bradley Schaefer, Margareta D. Pisarska, Jaime Vásquez, Juviannee I. Estrada-Veras, Boris Keren, Cyril Mignot, Leigh A. Flore, Irene V. Palafoll, Seth L. Alper, Richard P. Lifton, Shozeb Haider, Andres Moreno-De-Luca, Sheng Chih Jin, Waldemar Kolanus, and Kristopher T. Kahle. Brain: A Journal of Neurology, June, awae175.


Successful Diagnosis and Treatment of Traumatic Radiocarpal Translocation. Brown, Theodore M., Michael Sun, Michael Hausman, and David Kulber. Journal of Hand Surgery Global Online 6 (3): 404–8.

Extended-Release Versus Immediate-Release Triamcinolone Acetonide in Patients Who Have Knee Osteoarthritis and Type 2 Diabetes Mellitus. Spitzer, Andrew I., Helena W. Rodbard, Sheikh Usman Iqbal, Masato Nakazawa, Mary DiGiorgi, and Roy Winston. The Journal of Arthroplasty, May, S0883-5403(24)00527-8.

Biomechanical Evaluation of a Central Collinear Entry Reconstruction Nail for Femoral Neck Fracture Prophylaxis. Shah, Sapan, Dave T. Huang, Geoffrey Marecek, Kevin Huang, and Melodie F. Metzger. Injury 55 (8): 111640.

A Biological Spacer to Treat Irreparable Rotator Cuff Tears: A Biomechanical Study Utilizing a Secured Versus Unsecured Tensor Fascia Lata Graft. Malige, Ajith, James E. Tibone, Aaron Hui, Daniel Kwak, Josh Jewell, Michelle H. McGarry, and Thay Q. Lee. The American Journal of Sports Medicine, May, 3635465241252140.

Pathology and Laboratory Medicine

Stromal P16 and SATB2 Expression Does Not Distinguish Atypical Polypoid Adenomyoma (APA) From Its Benign Mimics. Bui, Chau Minh, Mahzad Azimpouran, Bonnie Balzer, Horacio Maluf, and Fabiola Medeiros. International Journal of Gynecological Pathology, May.

Comparative CKD Risk Prediction Using Homocitrulline and Carbamylated Albumin: Two Circulating Markers of Protein Carbamylation. Awwad, Aya, Eugene P. Rhee, Morgan Grams, Hernan Rincon Choles, James Sondheimer, Jiang He, Jing Chen, Chi-Yuan Hsu, Ramachandran S. Vasan, Paul L. Kimmel, Kendra Wulczyn, Anders Berg, Jim Lash, Mengyao Tang, Sahir Kalim, and CRIC Study Investigators. BMC Nephrology 25 (1): 185.

Robotic-Assisted Bronchoscopy for the Diagnosis of Lung Lesions: Experience With the Use of Frozen Sections as an Aid to Confirm the Localization of Lesions During the Procedure. Kanathanavanich, Manita, Xiaomo Li, Bernadette Boac, Shikha Bose, Ann E. Walts, Taryne Imai, George Chaux, Andrew Brownlee, and Alberto M. Marchevsky. Archives of Pathology & Laboratory Medicine, June.


Robotic-Assisted Left Lower Lobe Basilar Segmentectomy. Brownlee, Andrew R., Justin J. Watson, and Harmik J. Soukiasian. JTCVS Techniques 24 (April): 197–201.

Comparison of Outcomes Between Right and Left Upper Extremity Access in Endovascular Aortic Repair for Patients With Thoracoabdominal and Abdominal Aortic Aneurysms: A Systematic Review and Meta-Analysis. Goyal, Aman, Laveeza Fatima, Hritvik Jain, Muhammad Daoud Tariq, Fiza Mushtaq, Mahammed Z. Khan Suheb, Eileen Lu, Rozi Khan, and Amir Humza Sohail. Cardiology in Review, May.

ONECUT2 Is a Druggable Driver of Luminal to Basal Breast Cancer Plasticity. Zamora, Irene, Mirian Gutiérrez, Alex Pascual, María J. Pajares, Miguel Barajas, Lillian M. Perez, Sungyong You, Beatrice S. Knudsen, Michael R. Freeman, Ignacio J. Encío, and Mirja Rotinen. Cellular Oncology (Dordrecht), May.

Regarding Sentinel Lymph Node Biopsy in Younger and Older Patients. Faries, M. B., A. Varey, D. A. Elashoff, S. Lo, and J. F. Thompson. Journal of the European Academy of Dermatology and Venereology: JEADV, June.

A Global Consensus on the Definitions, Diagnosis and Management of Fibrostenosing Small Bowel Crohn’s Disease in Clinical Practice. Bettenworth, Dominik, Mark E. Baker, Joel G. Fletcher, Vipul Jairath, Cathy Lu, Willem Bemelman, Geert d’Haens, Andre d’Hoore, Axel Dignass, Iris Dotan, Roger Feakins, Phillip Fleshner, Christina Ha, Gaylyn Henderson, Ruishen Lyu, Julian Panes, Gerhard Rogler, Ren Mao, Jordi Rimola, William J. Sandborn, Siew C. Ng, Britta Siegmund, Mark Silverberg, Stuart A. Taylor, Bram Verstockt, Ilyssa O. Gordon, David H. Bruining, Brian G. Feagan, Florian Rieder, and Stenosis Therapy Anti-Fibrotic Research (STAR) Consortium. Nature Reviews. Gastroenterology & Hepatology, June.