This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published June 13-20. 

Biomedical Sciences

Gut Microbiome and Cardiometabolic Comorbidities in People Living With HIV. Trøseid, Marius, Susanne Dam Nielsen, and Ivan Vujkovic-Cvijin. Microbiome 12 (1): 106.

Variation of Computed Tomography-Derived Extracellular Volume Fraction and the Impact of Protocol Parameters: A Systematic Review and Meta-Analysis. Muthalaly, Rahul G., Sean Tan, Adam J. Nelson, Timothy Abrahams, Donghee Han, Balaji K. Tamarappoo, Damini Dey, Stephen J. Nicholls, Andrew Lin, and Nitesh Nerlekar. Journal of Cardiovascular Computed Tomography, June, S1934-5925(24)00344-7.

Level of Perivascular Inflammation Is Significantly Lower Around the Left Internal Mammary Artery Than Around Native Coronary Arteries. Yuki, Haruhito, Thoralf M. Sundt, Takayuki Niida, Keishi Suzuki, Daisuke Kinoshita, Daichi Fujimoto, Damini Dey, Hang Lee, Iris McNulty, Toru Naganuma, Sunao Nakamura, Eisuke Usui, Tsunekazu Kakuta, and Ik-Kyung Jang. Journal of the American Heart Association 13 (12): e033224.

Chronic Health Conditions, Disability, and Physical and Cognitive Limitations Among LGBTQ+ Cancer Survivors. Waters, Austin R., Mu Jin, Shaun R. Jones, Geetanjali D. Datta, Ebonee N. Butler, Erin E. Kent, Hazel B. Nichols, and Kelly Tan. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, June.

Cardiac Surgery

American Heart Association Cardiogenic Shock Registry: Design and Implementation. Morrow, David A., Mariell Jessup, William T. Abraham, Michael Acker, Angeline Aringo, Wayne Batchelor, Joanna Chikwe, Shaina Costello, Stavros G. Drakos, Steven Farmer, Annetine Gelijns, Nicole Gillette, Judith S. Hochman, Maria Isler, Navin K. Kapur, Arman Kilic, Robert Kormos, Eldrin F. Lewis, JoAnn Lindenfeld, Pierluca Lombardi, Donna Mancini, Sunil V. Rao, Christine Rutan, Marc Samsky, and Mitchell W. Krucoff. Circulation. Cardiovascular Quality and Outcomes, June, e010637.

Cardiology

Aortic Health and Coronary Function in Women With Suspected Ischemia and Non-Obstructive Coronary Artery Disease. Paquin, Amélie, Panteha Rezaeian, Yujie Cui, Michael D Nelson, Chrisandra Shufelt, Thais Coutinho, Martha Gulati, Jenna Maughan, John W. Petersen, R. David Anderson, Janet Wei, and C. Noel Bairey Merz. The Canadian Journal of Cardiology, June, S0828-282X(24)00436-7.

Skin Sympathetic Nerve Activity in Symptomatic and Asymptomatic Paroxysmal Atrial Fibrillation. Mao, Jessica, Xiao Liu, Anxhela Kote, Taiga Andersson, Xiaochun Li, Christine M. Albert, and Peng-Sheng Chen. Heart Rhythm, June, S1547-5271(24)02698-5.

Acoustic Ejection Mass Spectrometry Empowers Ultra-Fast Protein Biomarker Quantification. Van Puyvelde, Bart, Christie L. Hunter, Maxim Zhgamadze, Sudha Savant, Y. Oliver Wang, Esthelle Hoedt, Koen Raedschelders, Matt Pope, Carissa A. Huynh, V. Krishnan Ramanujan, Warren Tourtellotte, Morteza Razavi, N. Leigh Anderson, Geert Martens, Dieter Deforce, Qin Fu, Maarten Dhaenens, and Jennifer E. Van Eyk. Nature Communications 15 (1): 5114.

Endogenous Androgens, Coronary Atheroma and Remodeling in Women With Suspected Ischemic Heart Disease: A Report From the Women’s Ischemia Syndrome Evaluation (WISE) Study. Ranasinghe, Sachini, Ankur Jain, Yasmeen Taha, Eileen Handberg, B. Delia Johnson, Vera Bittner, George Sopko, Carl J. Pepine, R. David Anderson, and C. Noel Bairey Merz. American Heart Journal Plus: Cardiology Research and Practice 43 (July): 100411.

Computational Biomedicine

Sex Classification of 3D Skull Images Using Deep Neural Networks. Noel, Lake, Shelby Chun Fat, Jason L. Causey, Wei Dong, Jonathan Stubblefield, Kathryn Szymanski, Jui-Hsuan Chang, Paul Zhiping Wang, Jason H. Moore, Edward Ray, and Xiuzhen Huang. Scientific Reports 14 (1): 13707.

Using GPT-4 to Write a Scientific Review Article: A Pilot Evaluation Study. Wang, Zhiping Paul, Priyanka Bhandary, Yizhou Wang, and Jason H. Moore. BioData Mining 17 (1): 16.

Emergency Medicine

A Guide to Caring for Patients Who Identify as Transgender and Gender Diverse in the Emergency Department. Jardine, Logan, Courtney Edwards, Hannah Janeway, Chance Krempasky, Wendy Macias-Konstantopoulos, Paula Whiteman, and Antony Hsu. Journal of the American College of Emergency Physicians Open 5 (3): e13217.

Acute Abdominal Pain and a Whirlpool Sign on Computed Tomography: A Case Report. Libby, Christopher, Evan Stern, and Robyn Hoelle. Clinical Practice and Cases in Emergency Medicine 8 (2): 99–101.

Imaging

Image-Guided Minimally Invasive Treatment Options for Degenerative Lumbar Spine Disease: A Practical Overview of Current Possibilities. Taninokuchi Tomassoni, Makoto, Lorenzo Braccischi, Mattia Russo, Francesco Adduci, Davide Calautti, Marco Girolami, Fabio Vita, Alberto Ruffilli, Marco Manzetti, Federico Ponti, George R. Matcuk, Cristina Mosconi, Luigi Cirillo, Marco Miceli, and Paolo Spinnato. Diagnostics (Basel, Switzerland) 14 (11): 1147.

Medicine

Strategies to Improve the Impact of Artificial Intelligence on Health Equity: Scoping Review. Berdahl, Carl Thomas, Lawrence Baker, Sean Mann, Osonde Osoba, and Federico Girosi. Jmir Ai 2 (February): e42936.

Translational Studies Reveal the Divergent Effects of Simtuzumab Targeting LOXL2 in Idiopathic Pulmonary Fibrosis. Espindola, Milena S., David M. Habiel, Ana Lucia Coelho, Tanyalak Parimon, Peter Chen, Amanda Mikels-Vigdal, and Cory M. Hogaboam. Fibrosis (Hong Kong, China) 1 (2): 10007.

Childhood Cancer Incidence and Survival in South Australia and the Northern Territory, 1990-2017, With Emphasis on Indigenous Peoples. Mashtoub, Suzanne, Shahid Ullah, Anne Collinson, Gurmeet R. Singh, Justine Clark Adnyamathanha, Shalem Leemaqz, Ora Paltiel, David M. Roder, Benjamin Saxon, Ross McKinnon, Stephen J. Pandol, Claire T. Roberts, and Savio George Barreto. Cancers 16 (11): 2057.

Effect of Holder Pasteurization, Mode of Delivery, and Infant’s Gender on Fatty Acid Composition of Donor Breast Milk. Vass, Réka Anna, Miaomiao Zhang, Livia Simon Sarkadi, Márta Üveges, Judit Tormási, Eszter L. Benes, Tibor Ertl, and Sandor G. Vari. Nutrients 16 (11): 1689.

Food Insecurity in Hispanic Populations Is Associated With an Increased Risk of Hepatic Steatosis: A Nationally Representative Study. Niezen, Sebastian, Daniela Goyes, Aarshi Vipani, Ju Dong Yang, Walid S. Ayoub, Alexander Kuo, Michelle T. Long, and Hirsh D. Trivedi. Journal of Clinical Medicine 13 (11): 3206.

The Burden of Overweight and Obesity-Associated Gastrointestinal Cancers in Low and Lower-Middle-Income Countries: A Global Burden of Disease 2019 Analysis. Danpanichkul, Pojsakorn, Thanida Auttapracha, Banthoon Sukphutanan, Cheng Han Ng, Phuuwadith Wattanachayakul, Siwanart Kongarin, Priyata Dutta, Kwanjit Duangsonk, Jerapas Thongpiya, Mark D. Muthiah, Daniel Q. Huang, Rashid N. Lui, Yuya Seko, Hirokazu Takahashi, Mazen Noureddin, Ju Dong Yang, Michael B. Wallace, and Karn Wijarnpreecha. ACG 119 (6): 1177.

SHEA Position Statement on Pandemic Preparedness for Policymakers: The Role of Healthcare Epidemiologists in Communicating During Infectious Diseases Outbreaks. Shenoy, Erica S., David B. Banach, Lynne Jones Batshon, Westyn Branch-Elliman, Ghinwa Dumyati, Sarah Haessler, Vincent P. Hsu, Robin L. P. Jump, Anurag N. Malani, Trini A. Mathew, Rekha K. Murthy, Steven A. Pergam, Matthew Wayne Seeger, and David J. Weber. Infection Control & Hospital Epidemiology, June, 1–5.

Perianal Fistulizing Crohn’s Disease-Associated Anorectal and Fistula Cancers: Systematic Review and Expert Consensus. Wong, Serre-Yu, Cathy Rowan, Elvira Diaz Brockmans, Cindy Cy Law, Elisabeth Giselbrecht, Celina Ang, Sergey Khaitov, David Sachar, Leon Shin-Han Winata, Bram Verstockt, Antonino Spinelli, David T. Rubin, Parakkal Deepak, Dermot P. B. McGovern, Benjamin D. McDonald, Phillip Lung, Lilli Lundby, Amy L. Lightner, Stefan D. Holubar, Luke Hanna, Carla Hamarth, Jeroen Geldof, Anders Dige, Benjamin L. Cohen, Michele Carvello, Cristiana Bonifacio, Gabriele Bislenghi, Corina Behrenbruch, David H. Ballard, Emre Altinmakas, Shaji Sebastian, Phil Tozer, Ailsa Hart, and Jean-Frederic Colombel. Clinical Gastroenterology and Hepatology, June, S1542-3565(24)00504-4.

Plummer-Vinson Syndrome: Classic Triad of Iron Deficiency Anemia, Dysphagia, and Esophageal Webs. Mamzhi, Yakov, Richard Sukov, and Amrit K. Kamboj. Clinical Gastroenterology and Hepatology, June, S1542-3565(24)00510-X.

MafG/MYH9-LCN2 Axis Promotes Liver Fibrosis Through Inhibiting Ferroptosis of Hepatic Stellate Cells. Deng, Yalan, Liqing Lu, Dandan Zhu, Huajun Zhang, Ying Fu, Yuying Tan, Xuemei Tan, Ming Guo, Ye Zhang, Heping Yang, Bing Yang, Ting Liu, and Yongheng Chen. Cell Death and Differentiation, June.

Neoadjuvant Talazoparib in Patients With Germline BRCA1/2 Mutation-Positive, Early-Stage Triple-Negative Breast Cancer: Exploration of Tumor BRCA Mutational Status. Telli, Melinda L., Jennifer K. Litton, J. Thaddeus Beck, Jason M. Jones, Jay Andersen, Lida A. Mina, Raymond Brig, Michael Danso, Yuan Yuan, William F. Symmans, Julia F. Hopkins, Lee A. Albacker, Antonello Abbattista, Kay Noonan, Marielena Mata, A. Douglas Laird, and Joanne L. Blum. Breast Cancer (Tokyo, Japan), June.

Intraabdominal Adhesions Due to Missed Appendicitis as a Cause of Chronic Foregut Symptoms. Mehravar, Sepideh, and Ali Rezaie. Digestive Diseases and Sciences, June.

Impact of Prior Biologic or Janus Kinase Inhibitor Therapy on Efficacy and Safety of Etrasimod in the ELEVATE UC 52 and ELEVATE UC 12 Trials. Vermeire, Séverine, Bruce E. Sands, Laurent Peyrin-Biroulet, Geert R. D’Haens, Julian Panés, Andres J. Yarur, Douglas C. Wolf, Timothy Ritter, Stefan Schreiber, John C. Woolcott, Irene Modesto, Michael Keating, Kevin Shan, Joseph Wu, Michael V. Chiorean, Filip Baert, Marla C. Dubinsky, Martina Goetsch, Silvio Danese, and Brian G. Feagan. Journal of Crohn’s & Colitis, June, jjae079.

Hepatitis B Transmission/Reactivation Associated With Hepatitis B Core Antibody and Hepatitis C Nucleic Acid Testing Positive Organs: A Report From the Organ Procurement and Transplantation Network Disease Transmission Advisory Committee. Te, Helen S., Dong Heun Lee, Ann E. Woolley, Maheen Z. Abidi, Cynthia Fisher, Marty T. Sellers, Sarah Taimur, Taylor Livelli, Tamika Watkins, Dzhuliyana Handarova, Gerald J. Berry, Riki Graves, Chak-Sum Ho, Anna L. Hughart, Michelle Kittleson, Charles C. Marboe, Rachel A. Miller, Tanvi S. Sharma, Anil J. Trindade, R. Patrick Wood, Lorenzo N. Zaffiri, Stephanie M. Pouch, and Lara Danziger-Isakov. Transplant Infectious Disease, June, e14305.

Progression-Free Survival End Points in Prostate Cancer: Are We Truly Making Progress. Madan, Ravi A., Edwin M. Posadas, and Richard J. Lee. Nature Reviews. Urology, June.

Banff 2022 Kidney Commentary: Reflections and Future Directions. Rabant, Marion, Benjamin A. Adam, Olivier Aubert, Georg A. Böhmig, Marian Clahsen Van-Groningen, Lynn D. Cornell, Aiko P. J. de Vries, Edmund Huang, Nicolas Kozakowski, Agnieszka Perkowska-Ptasinska, Leonardo V. Riella, Ivy A. Rosales, Carrie Schinstock, Naomi Simmonds, Olivier Thaunat, and Michelle Willicombe. Transplantation, June.

Geographic and Racial Variability in Kidney, Cardiovascular and Safety Outcomes With Canagliflozin: A Secondary Analysis of the CREDENCE Randomized Trial. Cardoza, Kathryn, Amy Kang, Brendan Smyth, Tae Won Yi, Carol Pollock, Rajiv Agarwal, George Bakris, David M. Charytan, Dick de Zeeuw, David C. Wheeler, Hong Zhang, Christopher P. Cannon, Vlado Perkovic, Clare Arnott, Adeera Levin, and Kenneth W. Mahaffey. Diabetes, Obesity & Metabolism, June.

Development and Validation of a Biomarker Index for HCC Treatment Response. Liang, Jeff, Po-Yi Li, Joshua Norman, Marie Lauzon, Yee Hui Yeo, Hirsh Trivedi, Walid S. Ayoub, Alexander Kuo, Marc L. Friedman, Kamya Sankar, Jun Gong, Arsen Osipov, Andrew Hendifar, Tsuyoshi Todo, Irene Kim, Georgios Voidonikolas, Todd V. Brennan, Steven A. Wisel, Justin Steggarda, Kambiz Kosari, Rola Saouaf, Nicholas Nissen, Francis Yao, Neil Mehta, and Ju Dong Yang. Hepatology Communications 8 (7): e0466.

Panel Stacking Is a Threat to Consensus Statement Validity. Kepp, Kasper P., Preben Aavitsland, Marcel Ballin, Francois Balloux, Stefan Baral, Kevin Bardosh, Howard Bauchner, Eran Bendavid, Raj Bhopal, Daniel T. Blumstein, Paolo Boffetta, Florence Bourgeois, John P. A. Ioannidis, et al. Journal of Clinical Epidemiology, June, 111428.

Neurology

Incidence and Types of Cardiac Arrhythmias in the Peri-Ictal Period in Patients Having a Generalized Convulsive Seizure. Vilella, Laura, Christina Y. Miyake, Ganne Chaitanya, Johnson P. Hampson, Shirin Jamal Omidi, Manuela Ochoa-Urrea, Blanca Talavera, Oscar Mancera, Norma J. Hupp, Jaison S. Hampson, M. R. Sandhya Rani, Nuria Lacuey, Shiqiang Tao, Rup K. Sainju, Daniel Friedman, Maromi Nei, Catherine A. Scott, Brian Gehlbach, Stephan U. Schuele, Jennifer A. Ogren, Ronald M. Harper, Beate Diehl, Lisa M. Bateman, Orrin Devinsky, George B. Richerson, Guo-Qiang Zhang, and Samden D. Lhatoo. Neurology 103 (1): e209501.

Neurosurgery

Lateral Spinal CSF Leaks in Patients With Spontaneous Intracranial Hypotension: Radiologic-Anatomic Study of Different Variants. Schievink, Wouter I., Marcel M. Maya, Angelique Sao-Mai S. Tay, Rachelle B. Taché, Ravi S. Prasad, Vikram Wadhwa, and Miriam Nuño. AJNR. American Journal of Neuroradiology, June.

Focal Motor Weakness and Recovery Following Chronic Subdural Hematoma Evacuation. Nisson, Peyton L., John Francis, Michelot Michel, Surya Patil, Hiroki Uchikawa, Anand Veeravagu, and David Bonda. Journal of Neurosurgery, June, 1–8.

OBGYN

Female Genital Mutilation and Cutting: A Survey of Child Abuse Pediatricians. Pipes, Grace, Spencer Dunleavy, and Jocelyn Brown. BMC Women’s Health 24 (1): 348.

Pathology and Laboratory Medicine

ALK Inhibition With Alectinib for Refractory Metastatic Renal Cell Carcinoma With ALK Rearrangement: A Rare Case Report and Literature Review. Kathuria-Prakash, Nikhita, Lidia P. Lopez, Steven Raman, Huihui Ye, Jordan Anaokar, Anthony Sisk, Allan J. Pantuck, and Alexandra Drakaki. JCO Precision Oncology 8 (June): e2400154.

Papillary Renal Neoplasm With Reverse Polarity Has Low Frequency of Alterations in Chromosomes 7, 17, and Y. Kiyozawa, Daisuke, Takeshi Iwasaki, Dai Takamatsu, Kenichi Kohashi, Takumi Miyamoto, Genshiro Fukuchi, Masatoshi Eto, Michifumi Yamashita, and Yoshinao Oda. Virchows Archiv: An International Journal of Pathology, June.

Clinical Versus Histologic Margins for Cutaneous Squamous Cell Carcinoma: Comparing Outcomes for High-Risk Tumors Treated With Mohs Micrographic Surgery. Juhasz, Margit L. W., Amanda H. Rosenthal, Tuyet A. Nguyen, and Nima M. Gharavi. Dermatologic Surgery, June.

Corrigendum to ‘Androgen Deprivation and Radiotherapy With or Without Docetaxel for Localized High-Risk Prostat Cancer: Long-Term Follow-up From the Randomized NRG Oncology RTOG 0521 Trial’ [Eur. Eurol. 84(2) (2023) 156-163]. Sartor, Oliver, Theodore G. Karrison, Howard M. Sandler, Leonard G. Gomella, Mahul Amin, James Purdy, Jeff M. Michalski, Mark G. Garzotto, Nadeem Pervez, Alexander G. Balogh, George B. Rodrigues, Luis Souhami, M. Neil Reaume, Scott G. Williams, Raquibul Hannan, Christopher U. Jones, Eric M. Horwitz, Joseph P. Rodgers, Felix Y. Feng, and Seth A. Rosenthal. European Urology, June, S0302-2838(24)02443-6.

Pediatrics

Perceived Return on Investment of Accreditation by Accredited Programs. Smith, Mary Kay, Keith Beaulieu, Michele Kuszajewski, Tom LeMaster, Pooja Nawathe, Dawn M. Schocken, Jarrod Young, and Jack Jaeger. Simulation in Healthcare, September, 10.1097/SIH.0000000000000801.

Platelets in Kawasaki Disease: Mediators of Vascular Inflammation. Noval Rivas, Magali, Begüm Kocatürk, Bernardo S. Franklin, and Moshe Arditi. Nature Reviews Rheumatology, June.

Surgery

Organ Utilization Rates From Non-Ideal Donors for Solid Organ Transplant in the United States. Wisel, Steven A., Daniel Borja-Cacho, Dominick Megna, Michie Adjei, Irene K. Kim, and Justin A. Steggerda. Journal of Clinical Medicine 13 (11): 3271.

Advancements in Neuroendocrine Neoplasms: Imaging and Future Frontiers. Asmundo, Luigi, Francesco Rizzetto, Michael Blake, Mark Anderson, Amirkasra Mojtahed, William Bradley, Anuradha Shenoy-Bhangle, Carlos Fernandez-Del Castillo, Motaz Qadan, Cristina Ferrone, Jeffrey Clark, Valentina Ambrosini, Maria Picchio, Paola Mapelli, Laura Evangelista, Doris Leithner, Konstantin Nikolaou, Stephan Ursprung, Stefano Fanti, Angelo Vanzulli, and Onofrio Antonio Catalano. Journal of Clinical Medicine 13 (11): 3281.

Effect of Local Prolonged-Release Incisional Doxycycline on Surgical Site Infection Prophylaxis in Abdominal Colorectal Surgery: The SHIELD 1 Randomized Clinical Trial. Zmora, Oded, Phillip Fleshner, Philip S. Barie, Lior Segev, George M. Viola, Anthony J. Senagore, Antonino Spinelli, Olga Belotserkovsky, Shmuel Sharoni, Noam Emanuel, and SHIELD 1 Investigators. International Journal of Surgery (London, England), June.

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer: Results From the Phase II North American Multicenter Prospective Observational Trial. Donovan, Katherine F., Katherine C. Lee, Alison Ricardo, Natalie Berger, Antoinette Bonaccorso, Karim Alavi, Karen Zaghiyan, Alessio Pigazzi, Dana Sands, Teresa DeBeche-Adams, Sami A. Chadi, Elisabeth C. McLemore, John H. Marks, Justin A. Maykel, Sherief F. Shawki, Scott R. Steele, Matthew Albert, Mark Whiteford, Fu-Yuan Cheng, Steven D. Wexner, and Patricia Sylla. Annals of Surgery, June.

Robotic-Assisted Left Pneumonectomy. Soukiasian, Harmik J., and Andrew R. Brownlee. JTCVS Techniques 25 (June): 186–89.

Urology

Metabolic Response to Androgen Deprivation Therapy of Prostate Cancer. Chen, Yubin, Pao-Hwa Lin, Stephen J. Freedland, and Jen-Tsan Chi. Cancers 16 (11): 1991.

Patient Perceptions of Standardized Risk Language Used in American College of Radiology Prostate MRI PIRADS Scores. Dallmer, Jeremiah R., Michael Luu, Rola Saouaf, Brennan Spiegel, Stephen J. Freedland, and Timothy J. Daskivich. Journal of the American College of Radiology: JACR, June, S1546-1440(24)00518-0.