This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 31-Sept. 7.

Biomedical Sciences

Protein-Encapsulated Doxorubicin Reduces Cardiotoxicity in HiPSC-Cardiomyocytes and Cardiac Spheroids While Maintaining Anticancer Efficacy. Arzt, Madelyn, Bowen Gao, Maedeh Mozneb, Stephany Pohlman, Romina B. Cejas, Qizhi Liu, Faqing Huang, Changjun Yu, Yi Zhang, Xuemo Fan, Amelia Jenkins, Armando E. Giuliano, Paul W. Burridge, Xiaojiang Cui, and Arun Sharma. Stem Cell Reports, August, S2213-6711(23)00303-X.

Cardiometabolic Predictors of High-Risk CCTA Phenotype in a Diverse Patient Population. Kuno, Toshiki, Javier Arce, Michael Fattouh, Sharmila Sarkar, John P. Skendelas, Jonathan Daich, Aldo L. Schenone, Lili Zhang, Carlos J. Rodriguez, Salim S. Virani, Piotr J. Slomka, Leslee J. Shaw, Eric E. Williamson, Daniel S. Berman, Mario J. Garcia, Damini Dey, and Leandro Slipczuk. American Journal of Preventive Cardiology 15 (September): 100578.

Cardiology

Outcomes of Repeat Transcatheter Aortic Valve Replacement With Balloon-Expandable Valves: A Registry Study. Makkar, Raj R., Samir Kapadia, Tarun Chakravarty, Robert J. Cubeddu, Tsuyoshi Kaneko, Paul Mahoney, Dhairya Patel, Aakriti Gupta, Wen Cheng, Susheel Kodali, Deepak L. Bhatt, Michael J. Mack, Martin B. Leon, and Vinod H. Thourani. Lancet (London, England), August, S0140-6736(23)01636-7.

Computational Biomedicine

STAR_Outliers: A Python Package That Separates Univariate Outliers From Non-Normal Distributions. Gregg, John T., and Jason H. Moore. BioData Mining 16 (1): 25.

Medicine

Diagnosis and Management of Prolactin-Secreting Pituitary Adenomas: A Pituitary Society International Consensus Statement. Petersenn, Stephan, Maria Fleseriu, Felipe F. Casanueva, Andrea Giustina, Nienke Biermasz, Beverly M. K. Biller, Marcello Bronstein, Philippe Chanson, Hidenori Fukuoka, Monica Gadelha, Yona Greenman, Mark Gurnell, Ken K. Y. Ho, Jürgen Honegger, Adriana G. Ioachimescu, Ursula B. Kaiser, Niki Karavitaki, Laurence Katznelson, Maya Lodish, Dominique Maiter, Hani J. Marcus, Ann McCormack, Mark Molitch, Christopher A. Muir, Sebastian Neggers, Alberto M. Pereira, Rosario Pivonello, Kalmon Post, Gerald Raverot, Roberto Salvatori, Susan L. Samson, Ilan Shimon, Joanna Spencer-Segal, Greisa Vila, John Wass, and Shlomo Melmed. Nature Reviews. Endocrinology, September.

Estimating the Economic Burden of Osteoporotic Fractures in a Multinational Study: A Real-World Data Perspective. Moayyeri, A., J. Warden, S. Han, H. S. Suh, R. Pinedo-Villanueva, N. C. Harvey, J. R. Curtis, S. Silverman, J. K. Multani, and E. J. Yeh. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, August.

I AM FAMILY: Understanding the Adapted Sport Experiences of Family Members of Military Personnel With Physical and Psychological Illnesses and Injuries Through the Lens of the Invictus Games. Duong, Amber, Lauren Roberts, Heidi Cramm, M. Blair Evans, Emily Mayhew, Amy E. Latimer-Cheung, Alice Aiken, and Celina H. Shirazipour. Psychology of Sport and Exercise 68 (September): 102457.

Missing Voices: What Early Career Hospitalists View as Essential in Hospital Medicine-Focused Education. Nelson, Ryan E., Daniel N. Ricotta, Ali Farkhondehpour, Aram A. Namavar, Alan M. Hall, Brian K. Kwan, and Shannon K. Martin. Southern Medical Journal 116 (9): 739–44.

Association of Neighborhood Gentrification and Residential Moves With Hypertension and Diabetes Control in Los Angeles County, 2014-2019: A Retrospective Cohort Study. Chen, Katherine L., Frederick J. Zimmerman, Paul M. Ong, Andrea Jones, Teryl K. Nuckols, Ninez A. Ponce, Kristen R. Choi, Xia X. Li, Ariadna Padilla, and Claudia L. Nau. Health & Place 83 (September): 103109.

From Centimeters to Millimeters: The Evolution of the Surgical Margins for Melanoma-A Historical Review. Rosenthal, Amanda, Margit Juhasz, Gary Lask, and Nima Gharavi. Dermatologic Surgery, September.

Untargeted Metabolomic Analysis Investigating Links Between Unprocessed Red Meat Intake and Markers of Inflammation. Wood, Alexis C., Goncalo Graca, Meghana Gadgil, Mackenzie K. Senn, Matthew A. Allison, Ioanna Tzoulaki, Philip Greenland, Timothy Ebbels, Paul Elliott, Mark O. Goodarzi, Russell Tracy, Jerome I. Rotter, and David Herrington. The American Journal of Clinical Nutrition, September, S0002-9165(23)66116-7.

Virtual Reality Improves Symptoms of Functional Dyspepsia: Results of a Randomized, Double-Blind, Sham-Controlled, Pilot Study. Cangemi, David J., Marilia Montenegro, Brennan R. Spiegel, and Brian E. Lacy. The American Journal of Gastroenterology, September.

Could Some Patients With Fibromyalgia Potentially Have Hypophosphatasia? A Retrospective Single-Center Study. Injean, Patil, John Tan, Sandy Lee, and Christina Downey. ACR Open Rheumatology, September.

ChatGPT’s Ability to Comprehend and Answer Cirrhosis Related Questions in Arabic. Samaan, Jamil S., Yee Hui Yeo, Wee Han Ng, Peng-Sheng Ting, Hirsh Trivedi, Aarshi Vipani, Ju Dong Yang, Omer Liran, Brennan Spiegel, Alexander Kuo, and Walid S. Ayoub. Arab Journal of Gastroenterology, September, S1687-1979(23)00058-8.

RNA Binding Protein IGF2BP1 Synergizes With ETV6-RUNX1 to Drive Oncogenic Signaling in B-Cell Acute Lymphoblastic Leukemia. Sharma, Gunjan, Tiffany M. Tran, Ishu Bansal, Mohammad Sabique Beg, Ruchi Bhardwaj, Jaspal Bassi, Yuande Tan, Amit Kumar Jaiswal, Christine Tso, Ayushi Jain, Jay Singh, Parthaprasad Chattopadhyay, Archna Singh, Anita Chopra, Sameer Bakhshi, David Casero, Dinesh S. Rao, and Jayanth Kumar Palanichamy. Journal of Experimental & Clinical Cancer Research: CR 42 (1): 231.

Neurosurgery

Pseudarthrosis After Four-Level Anterior Cervical Discectomy and Fusion without Posterior Fixation. White, Michael D., S. Harrison Farber, Mark A. Pacult, Corey T. Walker, James J. Zhou, Juan S. Uribe, Steve Chang, Udaya K. Kakarla, and Jay D. Turner. Neurosurgical Focus 55 (3): E4.

Orthopaedics

Arthroscopic In Situ Biceps Tenodesis Using a Double Loop-and-Tack Knotless Suture Anchor. Chau, Michael, and Orr Limpisvasti. Arthroscopy Techniques 12 (8): e1437–42.

Republication of ‘Preliminary Experience Using Bioactive Glass Wedges for Cotton Osteotomy.’ Borenstein, Todd, Tyler Gonzalez, Janet Krevolin, Bryan Den Hartog, and David Thordarson. Foot & Ankle Orthopaedics 8 (3): 24730114231195360.

Increased Duration and Frequency of Lateral C-Arm Draping Does Not Increase Contamination Rates. Haggerty, Erin K., Harin B. Parikh, Zachary A. Rockov, David M. Hampton, Milton T. M. Little, Charles N. Moon, and Carol A. Lin. Journal of Surgical Orthopaedic Advances 32 (2): 107–10.

Pathology

Association of COVID-19 Versus COVID-19 Vaccination with Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study. Wang, Chia-Shi, Dorey A. Glenn, Margaret Helmuth, Abigail R. Smith, Andrew S. Bomback, Pietro A. Canetta, Gaia M. Coppock, Myda Khalid, Katherine R. Tuttle, Raed Bou-Matar, Larry A. Greenbaum, Bruce M. Robinson, Lawrence B. Holzman, William E. Smoyer, Michelle N. Rheault, Debbie Gipson, Laura H. Mariani, and Cure Glomerulonephropathy (CureGN) Study Consortium. American Journal of Kidney Diseases, August, S0272-6386(23)00773-4.

Pediatrics

Bcl-6 Expression by CD4+ T Cells Determines Concomitant Immunity and Host Resistance Across Distinct Parasitic Infections. Meli, Alexandre P., Gabriel A. Russell, Sharada Swaminathan, Laura Weichselbaum, Clara A. MacMahon, Erwan Pernet, Danielle Karo-Atar, Dakota Rogers, Annie Rochette, Ghislaine Fontes, Judith N. Mandl, Maziar Divangahi, Ophir D. Klein, Alex Gregorieff, Simona Stäger, and Irah L. King. Mucosal Immunology, August, S1933-0219(23)00066-1.

Interrater Reliability of the 2015 Pediatric Acute Lung Injury Consensus Conference Criteria for Pediatric ARDS. Silver, Layne, Daniel Kaplan, Jessica Asencio, Iris Mandell, Joanna Fishbein, and Sareen Shah. Chest, April, S0012-3692(23)00516-0.

Radiation Oncology

Atezolizumab Plus Stereotactic Ablative Radiotherapy for Medically Inoperable Patients with Early-Stage Non-Small Cell Lung Cancer: A Multi-Institutional Phase I Trial. Monjazeb, Arta M., Megan E. Daly, Guillaume Luxardi, Emanual Maverakis, Alexander A. Merleev, Alina I. Marusina, Alexander Borowsky, Amin Mirhadi, Stephen L. Shiao, Laurel Beckett, Shuai Chen, David Eastham, Tianhong Li, Logan V. Vick, Heather M. McGee, Frances Lara, Leslie Garcia, Leigh Anne Morris, Robert J. Canter, Jonathan W. Riess, Kurt A. Schalper, William J. Murphy, and Karen Kelly. Nature Communications 14 (1): 5332.

Surgery

Surgical Management of Substernal Thyroid Goiters. Bastien, Amanda J., and Allen S. Ho. Otolaryngologic Clinics of North America, August, S0030-6665(23)00128-7.

Prospective Randomized Trial of Immediate Postoperative Use of Regular Diet Versus Clear Liquid Diet in Major Colorectal Surgery. Yao, Lucille Y., Aimee E. Gough, Karen N. Zaghiyan, and Phillip R. Fleshner. Diseases of the Colon and Rectum, August.

Remission Strategies With Fat Grafting to Prevent Recurrence of Pedal Ulcerations and Pain: A Case Series. Kress, Gavin Thomas, Mark Swerdlow, Natasha Mohan, Ketan Patel, and Laura Shin. Plastic and Reconstructive Surgery. Global Open 11 (9): e5232.

Socioeconomic Disparities in Patients With Small Bowel Neuroendocrine Tumors. DiPeri, Timothy P., Nicholas Manguso, Jun Gong, Katelyn M. Atkins, Andrew E. Hendifar, and Alexandra Gangi. Journal of Surgical Oncology, September.