A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 17-24.
Anesthesiology
Racial and Socioeconomic Disparities in Kyphoplasty Among the Medicare Population. Krishnan, Sindhu, Ethan Y. Brovman, Mark R. Jones, Joseph Emanuele Manzi, Joshua Seokju Kim, Nikhilesh Rao, and Richard D. Urman. Pain Practice, August.
Biomedical Sciences
Enhancing Viability of Human Embryonic Stem Cells During Cryopreservation via RGD-REP-Mediated Activation of FAK/AKT/FoxO3a Signaling Pathway. Kim, Jeong Hee, Jeong In Choi, Young Hyun Che, Su Haeng Sung, Hojae Lee, Sun Lee, Jae-Hoon Park, Yun-Il Lee, Young-Sam Lee, Won Bae Jeon, and Yong Jun Kim. Tissue Engineering and Regenerative Medicine, August.
Sexual Orientation and Gender Identity Inequities in Cervical Cancer Screening by Race and Ethnicity. Lin, Emmeline, Patrycja Sleboda, Bobbie J. Rimel, Jarvis T. Chen, Diana V. Hernandez, and Geetanjali D. Datta. Cancer Causes & Control: CCC, August.
Temporal Changes in Coronary 18F-Fluoride Plaque Uptake in Patients With Coronary Atherosclerosis. Daghem, Marwa, Philip D. Adamson, Kang-Ling Wang, Mhairi Doris, Rong Bing, Edwin J. R. van Beek, Laura Forsyth, Michelle C. Williams, Evangelos Tzolos, Damini Dey, Piotr J. Slomka, Marc R. Dweck, David E. Newby, and Alastair J. Moss. Journal of Nuclear Medicine, Society of Nuclear Medicine, August, jnumed.122.264331.
Progenitor Diversity Defines Monocyte Roles. Goodridge, Helen S. Blood 142 (7): 617–19.
Cancer
Clinical Perspectives on the Optimal Use of Lenalidomide Plus Bortezomib and Dexamethasone for the Treatment of Newly Diagnosed Multiple Myeloma. Richardson, Paul G., Brian G. Durie, Laura Rosiñol, Maria-Victoria Mateos, Angela Dispenzieri, Philippe Moreau, Shaji Kumar, Noopur Raje, Nikhil Munshi, Jacob P. Laubach, Peter O’Gorman, Elizabeth O’Donnell, Peter Voorhees, Thierry Facon, Joan Bladé, Sagar Lonial, Aurore Perrot, and Kenneth C. Anderson. Haematologica, August.
Impact of Immune Tolerance Mechanisms on the Efficacy of Immunotherapy in Primary and Secondary Liver Cancers. Sankar, Kamya, Ashley N. Pearson, Tejaswi Worlikar, Matthew D. Perricone, Erin A. Holcomb, Mishal Mendiratta-Lala, Zhen Xu, Neil Bhowmick, and Michael D. Green. Translational Gastroenterology and Hepatology 8: 29.
Cardiac Surgery
Heart Transplantation in Patients From Socioeconomically Distressed Communities. Chen, Qiudong, Jad Malas, Dominic Emerson, Dominick Megna, Pedro Catarino, Fardad Esmailian, Joanna Chikwe, Lawrence S. Czer, Jon A. Kobashigawa, and Michael E. Bowdish. The Journal of Heart and Lung Transplantation, August, S1053-2498(23)01964-2.
Cardiology
Donor-Transmitted Coronary Artery Disease: Another Avenue to Expand Heart Transplantation? Cheng, Richard, Babak Azarbal, and Jason Smith. Journal of the American College of Cardiology 82 (9): 768–70.
Women, Lipids, and Atherosclerotic Cardiovascular Disease: A Call to Action From the European Atherosclerosis Society. Roeters van Lennep, Jeanine E., Lale S. Tokgözo?lu, Lina Badimon, Sandra M. Dumanski, Martha Gulati, Connie N. Hess, Kirsten B. Holven, Maryam Kavousi, Meral Kay?kç?o?lu, Esther Lutgens, Erin D. Michos, Eva Prescott, Jane K. Stock, Anne Tybjaerg-Hansen, Marieke J. H. Wermer, and Marianne Benn. European Heart Journal, August, ehad472.
Severe Aortic Stenosis Detection by Deep Learning Applied to Echocardiography. Holste, Gregory, Evangelos K. Oikonomou, Bobak J. Mortazavi, Andreas Coppi, Kamil F. Faridi, Edward J. Miller, John K. Forrest, Robert L. McNamara, Lucila Ohno-Machado, Neal Yuan, Aakriti Gupta, David Ouyang, Harlan M. Krumholz, Zhangyang Wang, and Rohan Khera. European Heart Journal, August, ehad456.
Functional Hypothalamic Amenorrhea and Preclinical Cardiovascular Disease. Shufelt, Chrisandra L., Mariam Saadedine, Galen Cook-Wiens, Margareta D. Pisarska, JoAnn E. Manson, Sarah L. Berga, Moshe Arditi, Prediman K. Shah, and C. Noel Bairey Merz. The Journal of Clinical Endocrinology and Metabolism, August, dgad498.
Chlorhexidine Gluconate Pocket Lavage to Prevent Cardiac Implantable Electronic Device Infection in High-Risk Procedures. Diaz, Juan Carlos, Eric D. Braunstein, Felipe Cañas, Mauricio Duque, Jorge Eduardo Marín, Julian Aristizabal, Cesar Daniel Niño, Oriana Bastidas, Carolina Hoyos, Nathaniel Steiger, Carlos D. Matos, William H. Sauer, and Jorge E. Romero. Heart Rhythm, August, S1547-5271(23)02585-7.
Correlates and Prognostic Implications of LVEF Reduction After Transcatheter Edge-to-Edge Repair for Primary Mitral Regurgitation. Shechter, Alon, Danon Kaewkes, Mirae Lee, Moody Makar, Vivek Patel, Ofir Koren, Keita Koseki, Takashi Nagasaka, Sabah Skaf, Tarun Chakravarty, Raj R. Makkar, and Robert J. Siegel. European Heart Journal. Cardiovascular Imaging, August, jead210.
Understanding and Investigating Sex-Based Differences in Heart Transplantation: A Call to Action. DeFilippis, Ersilia M., Andriana Nikolova, Luise Holzhauser, and Kiran K. Khush. JACC. Heart Failure, August, S2213-1779(23)00383-9.
Wild-Type Transthyretin Cardiac Amyloidosis in a Transplanted Heart. Stern, Lily K., Pamela A. Ivey, Corey J. Lum, Shayaan Zaidi, Daniel Luthringer, Angela Velleca, Jon A. Kobashigawa, Jignesh K. Patel, and Michelle M. Kittleson. JACC. Case Reports 19 (August): 101935.
Imaging
Opportunistic CT Screening-Machine Learning Algorithm Identifies Majority of Vertebral Compression Fractures: A Cohort Study. Page, John H., Franklin G. Moser, Marcel M. Maya, Ravi Prasad, and Barry D. Pressman. JBMR Plus 7 (8): e10778.
Deep Learning Image Segmentation Approaches for Malignant Bone Lesions: A Systematic Review and Meta-Analysis. Rich, Joseph M., Lokesh N. Bhardwaj, Aman Shah, Krish Gangal, Mohitha S. Rapaka, Assad A. Oberai, Brandon K. K. Fields, George R. Matcuk, and Vinay A. Duddalwar. Frontiers in Radiology 3: 1241651.
Medicine
Web-Based Video Education to Improve Uptake of Influenza Vaccination and Other Preventive Health Recommendations in Adults with Inflammatory Bowel Disease: Randomized Controlled Trial of Project PREVENT. Long, Millie D., Welmoed K. van Deen, Laura Weisbein, Carine Khalil, Keren L. Appel, Xian Zhang, Wenli Chen, Lori Zubrod, Robbie Maris, Afsoon Ghafari, Taylor Dupuy, Christina Y. Ha, Brennan M. R. Spiegel, Christopher V. Almario, and Gil Y. Melmed. Journal of Medical Internet Research 25 (August): e42921.
Immune Changes Induced by Periampullary Adenocarcinoma Are Reversed After Tumor Resection and Modulate the Postoperative Survival. Landerer, Anna, Ruth Himmelsbach, Esther A. Biesel, Stefan Fichtner-Feigl, Uwe A. Wittel, and Sophia Chikhladze. Discover. Oncology 14 (1): 153.
Hypoxia-Inducible Factor 1 Signaling Drives Placental Aging and Can Provoke Preterm Labor. Ciampa, Erin J., Padraich Flahardy, Harini Srinivasan, Christopher Jacobs, Linus Tsai, S. Ananth Karumanchi, and Samir M. Parikh. ELife 12 (August): RP85597.
Glasdegib Plus Intensive or Non-Intensive Chemotherapy for Untreated Acute Myeloid Leukemia: Results From the Randomized, Phase 3 BRIGHT AML 1019 Trial. Sekeres, Mikkael A., Pau Montesinos, Jan Novak, Jianxiang Wang, Deepa Jeyakumar, Benjamin Tomlinson, Jiri Mayer, Erin Jou, Tadeusz Robak, David C. Taussig, Hervé Dombret, Akil Merchant, Naveed Shaik, Thomas O’Brien, Whijae Roh, Xueli Liu, Wendy Ma, Christine G. DiRienzo, Geoffrey Chan, and Jorge E. Cortes. Leukemia, August.
Pituitary Adenoma or Neuroendocrine Tumour: The Need for an Integrated Prognostic Classification. Ho, Ken K. Y., Ursula B. Kaiser, Phillippe Chanson, Monica Gadelha, John Wass, Lynnette Nieman, Andrew Little, Manish K. Aghi, Lori Raetzman, Kalmon Post, Gerald Raverot, Alexander D. Borowsky, Dana Erickson, Justo P. Castaño, Edward R. Laws, Maria Chiara Zatelli, Jill Sisco, Laura Esserman, Kevin C. J. Yuen, Martin Reincke, and Shlomo Melmed. Nature Reviews. Endocrinology, August.
Prevalence and Burden of Illness of Rome IV Irritable Bowel Syndrome in the United States: Results From a Nationwide Cross-Sectional Study. Almario, Christopher V., Eden Sharabi, William D. Chey, Marie Lauzon, Carolyn S. Higgins, and Brennan M. R. Spiegel. Gastroenterology, August, S0016-5085(23)04889-8.
Operator-Specific Outcomes in Endoscopic Sleeve Gastroplasty: A Propensity-Matched Analysis of the US Population Using a Multicenter Database. Ali, Hassam, Faisal Inayat, Talia F. Malik, Pratik Patel, Gul Nawaz, Sobaan Taj, Attiq Ur Rehman, Arslan Afzal, Rizwan Ishtiaq, Muhammad Sohaib Afzal, Rashmi Advani, and Rabindra R. Watson. Proceedings (Baylor University. Medical Center) 36 (5): 592–99.
Neurosurgery
The Influence of Modifiable Risk Factors on Postoperative Outcomes in Patients Receiving Surgery for Resection for Acoustic Neuroma. Nasrollahi, Tasha S., Shane Shahrestani, Michela Borrelli, Martin L. Hopp, Arthur W. Wu, Dennis M. Tang, and John S. Yu. Ear, Nose, & Throat Journal, August, 1455613231191020.
OBGYN
A Biallelic Multiple Nucleotide Length Polymorphism Explains Functional Causality at 5p15.33 Prostate Cancer Risk Locus. Spisak, Sandor, Viktoria Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Balint Pataki, Dezso Ribli, Zsofia Sztupinszki, Connor Bell, Mersedeh Rohanizadegan, David R. Stillman, Sarah Abou Alaiwi, Alan B. Bartels, Marton Papp, Anamay Shetty, Forough Abbasi, Xianzhi Lin, Kate Lawrenson, Simon A. Gayther, Mark Pomerantz, Sylvan Baca, Norbert Solymosi, Istvan Csabai, Zoltan Szallasi, Alexander Gusev, and Matthew L. Freedman. Nature Communications 14 (1): 5118.
Risk of Preterm Delivery in Very Advanced Maternal Age Parturients Utilizing In-Vitro Fertilization. Newman, Rachel, Mariam Naqvi, Candace Levian, Sarah Smithson, and Tania Esakoff. American Journal of Perinatology, August.
Performance of ChatGPT in Medical Examinations: A Systematic Review and a Meta-Analysis. Levin, Gabriel, Nir Horesh, Yoav Brezinov, and Raanan Meyer. BJOG: An International Journal of Obstetrics and Gynaecology, August.
Orthopaedics
Changes in Sagittal Balance and Pre-Existing Junctional Angle Influence Development of Proximal Junctional Kyphosis in Growth Guidance Systems for Early-Onset Scoliosis. Arhewoh, Reme Emmanuel, Ian Marigi, Richard McCarthy, David Skaggs, Paul Sponseller, Scott Luhmann, and Pediatric Spine Study Group. Spine Deformity, August
Letter to the Editor: Grauberger et al, J Pediatr Orthop, 2020 and Sullivan et al, J Pediatr Orthop, 2020. Blakemore, Laurel, Sumeet Garg, Ryan Goodwin, J. Eric Gordon, Gregory Hahn, Charles T. Mehlman, Gregory Mencio, Karl Rathjen, Coleen Sabatini, Gregory Schmale, David L. Skaggs, and USNWR Pediatric Orthopaedic Working Group. Journal of Pediatric Orthopedics, August.
Pathology
Finding the Right Context of Use for Molecular Transplant Diagnostics in Kidney Allograft Biopsies. Mengel, Michael, and Mark Haas. Kidney International 104 (3): 423–25.
In Search of the Holy Grail of Artificial Hearts: Are We There Yet? Volod, Oksana, Modesto J. Colon, and Francisco A. Arabía. Seminars in Thrombosis and Hemostasis, August.
Radiation Oncology
Global Epidemiologic Patterns of Oropharyngeal Cancer Incidence Trends. Zumsteg, Zachary S., Michael Luu, Philip S. Rosenberg, Julia K. Elrod, Freddie Bray, Salvatore Vaccarella, Christopher Gay, Diana J. Lu, Michelle M. Chen, Anil K. Chaturvedi, and Marc T. Goodman. Journal of the National Cancer Institute, August, djad169.
Surgery
Perhaps Time for Some Appreciation of Good Old ‘NPO After Midnight.’ Baril, Donald T. Journal of Vascular Surgery 78 (3): 764–65.
Bioinformatics in Urology - Molecular Characterization of Pathophysiology and Response to Treatment. Hashemi Gheinani, Ali, Jina Kim, Sungyong You, and Rosalyn M. Adam. Nature Reviews. Urology, August.
Urology
The Impact of Race on Survival in Metastatic Prostate Cancer: A Systematic Literature Review. Freedland, Stephen J., Imtiaz A. Samjoo, Emily Rosta, Austin Lansing, Evelyn Worthington, Alexander Niyazov, Jonathan Nazari, and Bhakti Arondekar. Prostate Cancer and Prostatic Diseases, August.