The Buddha once described the two arrows of pain. The first arrow is the initial pain when one gets struck by an arrow. The second arrow represents the emotional component of pain and how one self-inflicts more suffering. Brennan Spiegel, MD, MSHS, director of health services research, is interested in the way the brain and gut communicate specifically in cases of IBS, and how virtual reality (VR) can help change a patient's perceptions of pain that are often amplified by fear and anxiety.

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