A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 19-26.
Anesthesiology
Obstetric Operating Room Staffing and Operating Efficiency Using Queueing Theory. Lim, Grace, Annamarie J. Lim, Beth Quinn, Brendan Carvalho, Mark Zakowski, and Grant C. Lynde. BMC Health Services Research 23 (1): 1147.
Biomedical Sciences
Longitudinal Association of Epicardial and Thoracic Adipose Tissues With Coronary and Cardiac Characteristics in Psoriasis. O’Hagan, Ross, Li-Yueh Hsu, Haiou Li, Christin G. Hong, Philip M. Parel, Alexander R. Berg, Grigory A. Manyak, Vy Bui, Nidhi H. Patel, Elizabeth M. Florida, Heather L. Teague, Martin P. Playford, Wunan Zhou, Damini Dey, Marcus Y. Chen, Nehal N. Mehta, and Alexander V. Sorokin. Heliyon 9 (10): e20732.
Quantification of Low-Attenuation Plaque Burden From Coronary CT Angiography: A Head-to-Head Comparison With Near-Infrared Spectroscopy Intravascular US. Tanisawa, Hiroki, Hidenari Matsumoto, Sebastien Cadet, Satoshi Higuchi, Hidefumi Ohya, Koji Isodono, Daisuke Irie, Kyoichi Kaneko, Arihiro Sumida, Takaho Hirano, Yuka Otaki, Ryoji Kitamura, Piotr J. Slomka, Damini Dey, and Toshiro Shinke. Radiology: Cardiothoracic Imaging 5 (5): e230090.
Cardiac Surgery
Safety and Outcomes Analysis: Transcatheter Implantation of Autologous Angiogenic Cell Precursors for the Treatment of Cardiomyopathy. Schubart, Jane R., Amirhossein Zare, Roberto M. Fernandez-de-Castro, Hector Rosario Figueroa, Ina Sarel, Kelly Tuchman, Kaitlyn Esposito, Fraser C. Henderson, and Ernst von Schwarz. Stem Cell Research & Therapy 14 (1): 308.
Preserved 2-y Liver Transplant Outcomes Following Simultaneous Thoracoabdominal DCD Organ Procurement Despite Effects on Liver Utilization Rate. Wisel, Steven A., Justin A. Steggerda, Carrie Thiessen, Garrett R. Roll, Qiudong Chen, Jason Thomas, Bhupinder Kaur, Pedro Catarino, Joanna Chikwe, and Irene K. Kim. Transplantation Direct 9 (11): e1528.
Cardiology
Leaflet Thrombosis in Transcatheter Aortic Valve Intervention: Mechanisms, Prevention and Treatment Options. Koren, Ofir, Vivek Patel, Tarun Chakravarty, Hasan Jilaihawi, Aakriti Gupta, Shirin Sadri, and Raj R. Makkar. Frontiers in Cardiovascular Medicine 10: 1249604.
The Association of Eicosanoids and Eicosanoid-Related Metabolites With Pulmonary Hypertension. McNeill, Jenna N., Athar Roshandelpoor, Mona Alotaibi, Arrush Choudhary, Mohit Jain, Susan Cheng, Shahrooz Zarbafian, Emily S. Lau, Gregory D. Lewis, and Jennifer E. Ho. The European Respiratory Journal 62 (4): 2300561.
Pregnancy as a Sentinel Event: Preventing Severe Maternal Morbidity in Heart Transplant Recipients. DeFilippis, Ersilia M., and Michelle M. Kittleson. JACC. Heart Failure, October, S2213-1779(23)00590-5.
The Mortality Burden of Untreated Aortic Stenosis. Généreux, Philippe, Rahul P. Sharma, Robert J. Cubeddu, Lucy Aaron, Omar M. Abdelfattah, Konstantinos P. Koulogiannis, Leo Marcoff, Mostafa Naguib, Samir R. Kapadia, Rajendra R. Makkar, Vinod H. Thourani, Benjamin S. van Boxtel, David J. Cohen, Michael Dobbles, Glenn R. Barnhart, Michelle Kwon, Philippe Pibarot, Martin B. Leon, and Linda D. Gillam. Journal of the American College of Cardiology, October, S0735-1097(23)07504-6.
A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue. Singh, Manisha, Debbie L. Teodorescu, Meagan Rowlett, Sophie X. Wang, Mercedes Balcells, Clara Park, Bruno Bernardo, Sian McGarel, Charlotte Reeves, Mandeep R. Mehra, Xuanhe Zhao, Hyunwoo Yuk, and Ellen T. Roche. Advanced Materials (Deerfield Beach, Fla.), October, e2307288.
Echocardiographic Characteristics of Left and Right Ventricular Longitudinal Function in Patients With a History of Cardiac Surgery. Kuwajima, Ken, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, and Takahiro Shiota. The American Journal of Cardiology, October, S0002-9149(23)01197-9.
Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years. Mack, Michael J., Martin B. Leon, Vinod H. Thourani, Philippe Pibarot, Rebecca T. Hahn, Philippe Genereux, Susheel K. Kodali, Samir R. Kapadia, David J. Cohen, Stuart J. Pocock, Michael Lu, Roseann White, Molly Szerlip, Julien Ternacle, S. Chris Malaisrie, Howard C. Herrmann, Wilson Y. Szeto, Mark J. Russo, Vasilis Babaliaros, Craig R. Smith, Philipp Blanke, John G. Webb, Raj Makkar, and PARTNER 3 Investigators. The New England Journal of Medicine, October.
Cardiovascular Fellowship Training in Cardio-Obstetrics: JACC Review Topic of the Week. Davis, Melinda B., Natalie A. Bello, Kathryn Berlacher, Colleen M. Harrington, Jeannette P. Lin, Kathryn J. Lindley, Lindsay G. Panah, Ki E. Park, Candice K. Silversides, Mary Norine Walsh, Gaby Weissman, Doreen DeFaria Yeh, and Julie B. Damp. Journal of the American College of Cardiology 82 (18): 1792–1803.
Reply: Beta-Blockers in Stable Ischemic Heart Disease. Godoy, Lucas C., Michael E. Farkouh, and Dennis T. Ko. Journal of the American College of Cardiology 82 (18): e169.
Imaging
Increasing Frequency of Dyspnea Among Patients Referred for Cardiac Stress Testing. Rozanski, Alan, Heidi Gransar, Sakul Sakul, Robert J. H. Miller, Donghee Han, Sean W. Hayes, John D. Friedman, Louise E. J. Thomson, and Daniel S. Berman. Journal of Nuclear Cardiology, October.
Medicine
Cardiac Re-Operation or Transcatheter Mitral Valve Replacement for Patients With Failed Mitral Prostheses. Ueyama, Hiroki A., Yoshihisa Miyamoto, Atsuyuki Watanabe, Hiroshi Gotanda, Stamatios Lerakis, Azeem Latib, Tsuyoshi Kaneko, Toshiki Kuno, and Yusuke Tsugawa. Journal of the American College of Cardiology, October, S0735-1097(23)07753-7.
Amivantamab Plus Chemotherapy With and Without Lazertinib in EGFR-Mutant Advanced NSCLC After Disease Progression on Osimertinib: Primary Results From the Phase 3 MARIPOSA-2 Study. Passaro, A., Jie Wang, Y. Wang, S.-H. Lee, B. Melosky, J.-Y. Shih, Jialei Wang, K. Azuma, O. Juan-Vidal, M. Cobo, E. Felip, N. Girard, A. B. Cortot, R. Califano, F. Cappuzzo, S. Owen, S. Popat, J.-L. Tan, J. Salinas, P. Tomasini, R. D. Gentzler, W. N. William, K. L. Reckamp, T. Takahashi, S. Ganguly, D. M. Kowalski, A. Bearz, M. MacKean, P. Barala, A. B. Bourla, A. Girvin, J. Greger, D. Millington, M. Withelder, J. Xie, T. Sun, S. Shah, B. Diorio, R. E. Knoblauch, J. M. Bauml, R. G. Campelo, and B. C. Cho. Annals of Oncology, October, S0923-7534(23)04281-3.
Comparison of Coronary Artery Calcium Scores Among Patients Referred for Cardiac Imaging Tests. Rozanski, Alan, Donghee Han, Robert J. H. Miller, Heidi Gransar, Piotr Slomka, Sean W. Hayes, John D. Friedman, Louise E. J. Thomson, and Daniel S. Berman. Progress in Cardiovascular Diseases, October, S0033-0620(23)00108-1.
Explainable Multilayer Graph Neural Network for Cancer Gene Prediction. Chatzianastasis, Michail, Michalis Vazirgiannis, and Zijun Zhang. Bioinformatics (Oxford, England), October, btad643.
Higher Maternal Body Mass Index Is Associated With Lower Placental Expression of EPYC: A Genome-Wide Transcriptomic Study. Sordillo, Joanne E., Frédérique White, Sana Majid, François Aguet, Kristin G. Ardlie, S. Ananth Karumanchi, Jose C. Florez, Camille E. Powe, Andrea G. Edlow, Luigi Bouchard, Pierre-Etienne Jacques, and Marie-France Hivert. The Journal of Clinical Endocrinology and Metabolism, October, dgad619.
Three-Year Overall Survival With Tebentafusp in Metastatic Uveal Melanoma. Hassel, Jessica C., Sophie Piperno-Neumann, Piotr Rutkowski, Jean-Francois Baurain, Max Schlaak, Marcus O. Butler, Ryan J. Sullivan, Reinhard Dummer, John M. Kirkwood, Marlana Orloff, Joseph J. Sacco, Sebastian Ochsenreither, Anthony M. Joshua, Lauris Gastaud, Brendan Curti, Josep M. Piulats, April K. S. Salama, Alexander N. Shoushtari, Lev Demidov, Mohammed Milhem, Bartosz Chmielowski, Kevin B. Kim, Richard D. Carvajal, Omid Hamid, Laura Collins, Koustubh Ranade, Chris Holland, Constance Pfeiffer, and Paul Nathan. The New England Journal of Medicine, October.
Candida Makes a Lasting Impression in COVID-19. Lagree, Katherine, and Peter Chen. Nature Immunology, October.
Beyond Titles: The Need to Reduce Prescribing Variation of Potentially Inappropriate Medications Among All Clinicians. Keller, Michelle S., and Catherine A. Sarkisian. Annals of Internal Medicine, October.
Emunas Chachamim (Faith in the Sages): A Prenatal Genetic Counseling Needs Assessment of Orthodox Jewish Clergy in Los Angeles. Richeimer, Natalie, Kaila Wilson, Alexandra Petrasek, and Jason Weiner. Journal of Genetic Counseling, October.
WIP1 Is a Novel Specific Target for Growth Hormone Action. Apaydin, Tugce, Svetlana Zonis, Cuiqi Zhou, Christian Wong Valencia, Robert Barrett, Ger J. Strous, Jan A. Mol, Vera Chesnokova, and Shlomo Melmed. iScience 26 (11): 108117.
Neurosurgery
Developing Mixed-Effects Models to Compare the Predictive Ability of Various Comorbidity Indices in a Contemporary Cohort of Patients Undergoing Lumbar Fusion. Shahrestani, Shane, Taylor Reardon, Nolan J. Brown, Cathleen C. Kuo, Julian Gendreau, Rohin Singh, Neal A. Patel, Dean Chou, and Andrew K. Chan. Neurosurgery, October.
Obstetrics and Gynecology
Association Between Acceptance of Routine Pregnancy Vaccinations and COVID-19 Vaccine Uptake in Pregnant Patients. Ha, Laura, Candace Levian, Naomi Greene, Ilona Goldfarb, Anna Hirsch, and Mariam Naqvi. The Journal of Infection, October, S0163-4453(23)00541-8.
Orthopaedics
Charcot-Marie-Tooth Disease: A Surgical Algorithm. Pfeffer, Glenn B., and Max P. Michalski. Foot and Ankle Clinics 28 (4): 857–71.
Pathology
Arginase-1 Is More Specific Than Hepatocyte Paraffin 1 for Differentiating Hepatocellular Carcinomas With Cytoplasmic Clearing From Nonhepatocellular Clear Cell Tumors in Liver Biopsies. Larson, Brent K., Deepti Dhall, and Maha Guindi. Applied Immunohistochemistry & Molecular Morphology: AIMM, October.
Chronic Dehydration Induces Injury Pathways in Rats, but Does Not Mimic Histopathology of Chronic Interstitial Nephritis in Agricultural Communities. Schreurs, Gerd, Stuart Maudsley, Cynthia Nast, Marleen Praet, Sylvina Da Silva Fernandes, Peter Boor, Patrick D’Haese, Marc E. De Broe, and Benjamin A. Vervaet. Scientific Reports 13 (1): 18119.
How Do We Design a Laboratory Space for a Hospital Transfusion Medicine Service? Allen, Elizabeth S., Ingrid Perez-Alvarez, Jennifer S. Woo, and Laura D. Stephens. Transfusion, October.
The Intricate Relationship Between H3K27 Trimethylation and Merkel Cell Polyomavirus Status in Merkel Cell Carcinoma. Krajisnik, Andrea, Neda Rezaee, Jessica Crystal, Eleanor R. Duncan, Bonnie L. Balzer, David P. Frishberg, and Wonwoo Shon. The American Journal of Dermatopathology 45 (11): 783–85.
Pediatrics
Loss of Humeral Immunity in Childhood Cancer Survivors Not Having Undergone Hematopoietic Stem Cell Transplantation. Pearson, Benjamin, Michelle Pulley, Marcio Diniz, Nicole Baca, and Fataneh Majlessipour. Cancer Reports (Hoboken, N.J.), October, e1907.
Urology
Serum Testosterone and Dihydrotestosterone and Incidence and Progression of Lower Urinary Tract Symptoms: Results From the REDUCE Study. Daniels, James P., James Mirocha, Michie Adjei, Daniel Moreira, and Stephen J. Freedland. The Journal of Urology, October, 101097JU0000000000003738.