This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 12-19.

Biomedical Sciences 

Editorial: Role of Angiotensin-Converting Enzyme in Myeloid Immune Functions. Cao, DuoYao, and Suguru Saito. Frontiers in Physiology 14: 1297995.

Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant Smoothened and GLI Into Glioma Primary Cilia. Shi, Ping, Jia Tian, Julianne C. Mallinger, Dahao Ling, Loic P. Deleyrolle, Jeremy C. McIntyre, Tamara Caspary, Joshua J. Breunig, and Matthew R. Sarkisian. Cells 12 (19): 2354.

Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus. Garcia, Gustavo, Nikhil Chakravarty, Sophia Paiola, Estrella Urena, Priya Gyani, Christopher Tse, Samuel W. French, Moise Danielpour, Joshua J. Breunig, David A. Nathanson, and Vaithilingaraja Arumugaswami. Cells 12 (19): 2384.

HIC1 Interacts With FOXP3 Multi Protein Complex: Novel Pleiotropic Mechanisms to Regulate Human Regulatory T Cell Differentiation and Function. Andrabi, Syed Bilal Ahmad, Kedar Batkulwar, Santosh D. Bhosale, Robert Moulder, Meraj Hasan Khan, Tanja Buchacher, Mohd Moin Khan, Ilona Arnkil, Omid Rasool, Alexander Marson, Ubaid Ullah Kalim, and Riitta Lahesmaa. Immunology Letters, October, S0165-2478(23)00144-X.

Ethical Aspects of the Disfavored Discharge. Tarsney, Preya S., Andy Kondrat, Kelsey Watters, Kristi L. Kirschner, Debjani Mukherjee, and Preya S. Tarsney. PM & R: The Journal of Injury, Function, and Rehabilitation, October.

Multidimensional School Features Associated With Physical Activity among Youth at Risk of Obesity: An Exploratory Principal Component and Generalized Estimating Equation Analysis. Bird, Madeleine, Tracie A. Barnett, Daniel Fuller, Deanna Chinerman, Marie-Ève Mathieu, and Geetanjali D. Datta. BMC Public Health 23 (1): 2010.

Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit. Sattler, Rita, Bryan J. Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J. Barmada, Clive N. Svendsen, Matthew D. Disney, Tania F. Gendron, Philip C. Wong, Martin R. Turner, Adam Boxer, Suma Babu, Michael Benatar, Michael Kurnellas, Jonathan D. Rohrer, Christopher J. Donnelly, Lynette M. Bustos, Kendall Van Keuren-Jensen, Penny A. Dacks, Marwan N. Sabbagh, and Attendees of the inaugural C9ORF72 FTD/ALS Summit. Neurology and Therapy, October.

Cardiac Surgery

Not If but How to Occlude the Left Atrial Appendage; That Is the Question. Own, Ali, and Armin Kiankhooy. The Annals of Thoracic Surgery, October, S0003-4975(23)01063-9.

Cardiology 

Marine N-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Ogata, Soshiro, JoAnn E. Manson, Jae H. Kang, Julie E. Buring, I.-Min Lee, Kunihiro Nishimura, Yasuhiko Sakata, Jacqueline Suk Danik, Denise D’Agostino, Samia Mora, Christine M. Albert, and Nancy R. Cook. Nutrients 15 (19): 4235.

Functional Hypothalamic Amenorrhea and Proinflammatory Cytokines. Saadedine, Mariam, Moshe Arditi, Galen Cook-Wiens, Doris A. Taylor, Margareta D. Pisarska, JoAnn E. Manson, Sarah L. Berga, Prediman K. Shah, C. Bairey Merz, and Chrisandra Shufelt. Fertility and Sterility, 79th Scientific Congress of the American Society for Reproductive Medicine, 120 (4, Supplement): e164.

Multidetector Computed Tomography in Patients Who Underwent Transcatheter Mitral Edge-to-Edge Repair. Kaewkes, Danon, Shunsuke Kagawa, Vivek Patel, Taku Omori, Keita Koseki, Ofir Koren, Sharon Shalom Natanzon, Alon Shechter, Hasan Jilaihawi, Tarun Chakravarty, Mamoo Nakamura, Moody Makar, Takahiro Shiota, and Raj Makkar. The American Journal of Cardiology 208 (October): 101–10.

Report of the 2022 Banff Heart Concurrent: Focus on Non-HLA Antibodies in Rejection and the Pathology of ‘Mixed’ Rejection. Fedrigo, Marny, Gerald J. Berry, Guillaume Coutance, Elaine F. Reed, Chieh-Yu Lin, Alessia Giarraputo, Evan Kransdorf, Olivier Thaunat, Martin Goddard, Annalisa Angelini, Desley Ah Neil, Patrick Bruneval, Jean-Paul Duong Van Huyen, Alexandre Loupy, and Dylan V. Miller. American Journal of Transplantation, October, S1600-6135(23)00794-3.

Combined Heart Liver Transplantation in the Patients With Advanced Liver Disease and/or Hepatocellular Carcinoma: Why Can’t Liver Pull the Heart? Shingina, Alexandra, Neha Bansal, Ari Cedars, Sharon Chen, Tami Daugherty, Juliet Emamaullee, Daniel Ganger, Jin Ge, Theo Heller, Dempsey Hughes, Joseph Kay, Juan Ortega Legaspi, Jonathan Menachem, Martin Montenovo, Jordan Sack, Leigh Reardon, Thomas Schiano, Kathleen Simpson, Jeffrey Teuteberg, Rose Tompkins, Irene Vodkin, Fred Wu, and George Lui. American Journal of Transplantation, October, S1600-6135(23)00798-0.

Does Bortezomib Influence Pre-Transplant Desensitization Therapy or Benefit Post-Heart Transplant Outcomes for Highly Sensitized Patients? Dhillon, Manvir, Jon A. Kobashigawa, Michelle Kittleson, Rashmi Jain, Nikhil Patel, Tahli Singer-Englar, Xiaohai Zhang, Matthew Hakimi, Tamar Aintablian, Robert Vescio, Deanna Dilibero, Evan Kransdorf, Lawrence Czer, Andriana P. Nikolova, and Jignesh K. Patel. Clinical Transplantation, October, e15165.

Air Pollution and Temperature: A Systematic Review of Ubiquitous Environmental Exposures and Sudden Cardiac Death. Borchert, William, Stephanie T. Grady, Jie Chen, Nicole V. DeVille, Charlotte Roscoe, Futu Chen, Carol Mita, Isabel Holland, Grete E. Wilt, Cindy R. Hu, Unnati Mehta, Rachel C. Nethery, Christine M. Albert, Francine Laden, and Jaime E. Hart. Current Environmental Health Reports, October.

Deep Learning of Electrocardiograms in Sinus Rhythm From US Veterans to Predict Atrial Fibrillation. Yuan, Neal, Grant Duffy, Sanket S. Dhruva, Adam Oesterle, Cara N. Pellegrini, John Theurer, Marzieh Vali, Paul A. Heidenreich, Salomeh Keyhani, and David Ouyang. JAMA Cardiology, October.

Impact of Guideline-Directed Statin Intervention for Primary Prevention in Patients With Diabetes. Muluk, Pallavi, Jianhui Zhu, Floyd Thoma, Eli Hay, Oscar Marroquin, Amber Makani, Aryan Aiyer, Khurram Nasir, Martha Gulati, Michael D. Shapiro, Suresh Mulukutla, and Anum Saeed. Diabetes Care, October, dc230816.

Psychosocial Factors of Women Presenting With Myocardial Infarction With or Without Obstructive Coronary Arteries. Hausvater, Anaïs, Tanya M. Spruill, Yuhe Xia, Nathaniel R. Smilowitz, Milla Arabadjian, Binita Shah, Ki Park, Caitlin Giesler, Kevin Marzo, Dwithiya Thomas, Janet Wei, Jeffrey Trost, Puja K. Mehta, Bryan Har, Kevin R. Bainey, Hua Zhong, Judith S. Hochman, and Harmony R. Reynolds. Journal of the American College of Cardiology 82 (17): 1649–58.

Computational Biomedicine

Post-Translational Modifications of Histone and Non-Histone Proteins in Epigenetic Regulation and Translational Applications in Alcohol-Associated Liver Disease: Challenges and Research Opportunities. Rungratanawanich, Wiramon, Jacob W. Ballway, Xin Wang, Kyoung-Jae Won, James P. Hardwick, and Byoung-Joon Song. Pharmacology & Therapeutics, October, 108547.

Medicine

Corrigendum: Regulatory Network and Interplay of Hepatokines, Stellakines, Myokines and Adipokines in Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis. Yang, Bing, Liqing Lu, Dongmei Zhou, Wei Fan, Lucía Barbier-Torres, Justin Steggerda, Heping Yang, and Xi Yang. Frontiers in Endocrinology 14: 1284809.

Progression-Free Survival of Daratumumab Versus Bortezomib Triplet Combination With Lenalidomide and Dexamethasone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma: TAURUS Chart Review Study. Gordan, Lucio Navarro, Carlyn Rose Tan, Robert Vescio, Jing Christine Ye, Carolina Schinke, Rohan Medhekar, Alex Z. Fu, Marie-Hélène Lafeuille, Philippe Thompson-Leduc, Vipin Khare, John Reitan, Gary Milkovich, Shuchita Kaila, Faith Davies, and Saad Z. Usmani. Clinical Lymphoma, Myeloma & Leukemia, September, S2152-2650(23)01550-1.

Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity. Caremoli, Filippo, Jennifer Huynh, Venu Lagishetty, Daniela Markovic, Jonathan Braun, Tien S. Dong, Jonathan P. Jacobs, and Catia Sternini. Nutrients 15 (19): 4145.

Society for Immunotherapy of Cancer (SITC) Clinical Practice Guideline on Immunotherapy for the Treatment of Melanoma, Version 3.0. Pavlick, Anna C., Charlotte E. Ariyan, Elizabeth I. Buchbinder, Diwakar Davar, Geoffrey T. Gibney, Omid Hamid, Tina J. Hieken, Benjamin Izar, Douglas B. Johnson, Rajan P. Kulkarni, Jason J. Luke, Tara C. Mitchell, Meghan J. Mooradian, Krista M. Rubin, April Ks Salama, Keisuke Shirai, Janis M. Taube, Hussein A. Tawbi, J. Keith Tolley, Caressa Valdueza, Sarah A. Weiss, Michael K. Wong, and Ryan J. Sullivan. Journal for Immunotherapy of Cancer 11 (10): e006947.

Tracheal and Bronchial Stent for Native Main Bronchus Laceration After Lung Transplantation. Pyarali, Fahim F., Alexander Yuen, George Chaux, Dominick J. Megna, Pedro A. Catarino, Lorenzo Zaffiri, and Reinaldo Rampolla. JTCVS Techniques 21 (October): 247–50.

‘I Can Control What I Do With My Daily Life’: Occupational Experiences of Adolescents and Young Adults With Li-Fraumeni Syndrome. Sleight, Alix G., Camella J. Rising, Patrick Boyd, Catherine Wilsnack, Margaret Goodfellow, Payal P. Khincha, and Allison Werner-Lin. Journal of Occupational Science 30 (4): 661–72.

A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies. Srinivasan, Shylaja, Peitao Wu, Josep M. Mercader, Miriam S. Udler, Bianca C. Porneala, Traci M. Bartz, James S. Floyd, Colleen Sitlani, Xiquing Guo, Jeffrey Haessler, Charles Kooperberg, Jun Liu, Shahzad Ahmad, Cornelia van Duijn, Ching-Ti Liu, Mark O. Goodarzi, Jose C. Florez, James B. Meigs, Jerome I. Rotter, Stephen S. Rich, Josée Dupuis, and Aaron Leong. Journal of the Endocrine Society 7 (11): bvad123.

Prospective and Mendelian Randomization Analyses on the Association of Circulating Fatty Acid Binding Protein 4 (FABP-4) and Risk of Colorectal Cancer. Nimptsch, Katharina, Krasimira Aleksandrova, Thu Thi Pham, Nikos Papadimitriou, Jürgen Janke, Sofia Christakoudi, Alicia Heath, Anja Olsen, Anne Tjønneland, Matthias B. Schulze, Verena Katzke, Rudolf Kaaks, Bethany van Guelpen, Justin Harbs, Domenico Palli, Alessandra Macciotta, Fabrizio Pasanisi, Sandra Milena Colorado Yohar, Marcela Guevara, Pilar Amiano, Sara Grioni, Paula Gabriela Jakszyn, Jane C. Figueiredo, N. Jewel Samadder, Christopher I. Li, Victor Moreno, John D. Potter, Robert E. Schoen, Caroline Y. Um, Elisabete Weiderpass, Mazda Jenab, Marc J. Gunter, and Tobias Pischon. BMC Medicine 21 (1): 391.

Top Ten Tips Palliative Care Clinicians Should Know About Physical Therapy, Occupational Therapy, and Speech Language Pathology. Habib, Muhammad Hamza, Jasmine Zheng, Ahmed Radwan, Dorothy W. Tolchin, Sean Smith, Rebecca S. Inzana, Tamra Keeney, Arpit Arora, Akinpelumi Beckley, Shaloo Choudhary, Christopher A. Jones, and Mathias Schlögl. Journal of Palliative Medicine, October.

Development of a Model to Identify Patients Who Do Not Need Oesophageal Biopsies When Eosinophilic Oesophagitis Is Suspected. Kamboj, Amrit K., Cary C. Cotton, Liang Yen Liu, June Tome, Diana L. Snyder, Jeffrey A. Alexander, Karthik Ravi, William S. Harmsen, Evan S. Dellon, and David A. Katzka. Alimentary Pharmacology & Therapeutics, October.

Multi-Omic Profiling Reveals Early Immunological Indicators for Identifying COVID-19 Progressors. Drake, Katherine A., Dimitri Talantov, Gary J. Tong, Jack T. Lin, Simon Verheijden, Samuel Katz, Jacqueline M. Leung, Benjamin Yuen, Vinod Krishna, Michelle J. Wu, Alex Sutherland, Sarah A. Short, Pouya Kheradpour, Maxwell Mumbach, Kate M. Franz, Vladimir Trifonov, Molly V. Lucas, James Merson, Charles C. Kim, and PRESCO Study Group. Clinical Immunology (Orlando, Fla.), October, 109808.

Quantifying EHR and Policy Factors Associated With the Gender Productivity Gap in Ambulatory, General Internal Medicine. Li, Huan, Lisa Rotenstein, Molly M. Jeffery, Hyung Paek, Bidisha Nath, Brian L. Williams, Robert M. McLean, Richard Goldstein, Teryl K. Nuckols, Lalima Hoq, and Edward R. Melnick. Journal of General Internal Medicine, October.

Review of Radiofrequency Microneedling: History, Devices and Uses. Kneiber, Diana, Mina Amin, Tuyet A. Nguyen, and Nima M. Gharavi. Journal of Cosmetic and Laser Therapy, October, 1–6.

Comparison of the Prognostic Value Between Quantification and Visual Estimation of Coronary Calcification From Attenuation CT in Patients Undergoing SPECT Myocardial Perfusion Imaging. Feher, Attila, Konrad Pieszko, Aakash Shanbhag, Mark Lemley, Robert Jh Miller, Cathleen Huang, Leonidas Miras, Yi-Hwa Liu, Jamie Gerber, Albert J. Sinusas, Edward J. Miller, and Piotr J. Slomka. The International Journal of Cardiovascular Imaging, October.

Towards Responsible AI in Patient Education: Ethical, Linguistic, and Regulatory Considerations. Samaan, Jamil S., Yee Hui Yeo, Nithya Rajeev, Wee Han Ng, Nitin Srinivasan, and Kamran Samakar. Obesity Surgery, October.

Profiling the Inflammatory Bowel Diseases Using Genetics, Serum Biomarkers, and Smoking Information. Liu, Ruize, Dalin Li, Talin Haritunians, Yunfeng Ruan, Mark J. Daly, Hailiang Huang, and Dermot P. B. McGovern. iScience 26 (10): 108053.

Modulating Microbiome-Immune Axis in the Deployment-Related Chronic Diseases of Veterans: Report of an Expert Meeting. Sun, Jun, M. Nedim Ince, Clara Abraham, Terrence Barrett, Lisa A. Brenner, Yingzi Cong, Reza Dashti, Pradeep K. Dudeja, David Elliott, Thomas S. Griffith, Peter S. Heeger, Andrew Hoisington, Kaikobad Irani, Tae Kon Kim, Neeraj Kapur, Joseph Leventhal, Mansour Mohamadzadeh, Ece Mutlu, Rodney Newberry, Jonathan U. Peled, Israel Rubinstein, Salyka Sengsayadeth, Chen Sabrina Tan, Xiao-Di Tan, Eric Tkaczyk, Jason Wertheim, and Zheng Jenny Zhang. Gut Microbes 15 (2): 2267180.

Neurosurgery

Management of Tarlov Cysts: An Uncommon but Potentially Serious Spinal Column Disease-Review of the Literature and Experience With Over 1000 Referrals. Murphy, Kieran, Mehran Nasralla, Gaylene Pron, Khaled Almohaimede, and Wouter Schievink. Neuroradiology, October.

Obstetrics and Gynecology

Robotics in Gynecologic Oncology: Past, Present, and Future. Taylor, Kristin N., and Kenneth H. Kim. Journal of Gynecologic Surgery 39 (5): 204–12.

New Patient Fertility Consultation Trends Pre- and Post-Covid-19 Pandemic. Willson, Bryn E., Katherine Vanhise, Amelia M. Schaub, Katherine Moran, Ndeye Konate, Jessica L. Chan, Margareta D. Pisarska, and Erica T. Wang. Fertility and Sterility, 79th Scientific Congress of the American Society for Reproductive Medicine, 120 (4, Supplement): e265–66.

A Systematic Review of Genome Wide Analyses of Methylation Changes Associated With Assisted Reproductive Technologies in Various Tissues. Schaub, Amelia M., Tania L. Gonzalez, Anna E. Dorfman, Allynson G. Novoa, Rimsha A. Hussaini, Paige M. Harakuni, Mayaal H. Khan, Brandon J. Shabani, Akhila Swarna, Erica T. Wang, Jessica L. Chan, John Williams, and Margareta D. Pisarska. Fertility and Sterility, October, S0015-0282(23)01922-2.

Health System Decarbonization on Obstetric and Newborn Units. Emont, Jordan, Melissa Wang, and Kelly Wright. Seminars in Perinatology, October, 151844.

Orthopaedics 

Does Fibular Displacement Predict Tibial Malrotation in Simulated Tibia-Fibula Fractures. Robles, Abrianna S., Christian L. Blough, Steven Kurapaty, Anderson Lee, Brett A. Ewing, and Geoffrey S. Marecek. The Journal of the American Academy of Orthopaedic Surgeons, October.

Pathology 

Homozygous Deletion of the DSG3 Terminal Exon Associated With Acantholytic Blistering of the Oral and Laryngeal Mucosa. Jiang, Nan, Taylor B. Sewell, Theresa L. Kowalski, Aisha Rekab, Susannah Hills, Ladan Fazlollahi, Christine T. Lauren, Kimberly Morel, Lakshmi Mehta, and Jun Liao. American Journal of Medical Genetics. Part A, October.

Pediatrics 

Celebrations of Death. Pohl, Charles, and Lynne Le Holsclaw. Cancer Treatment and Research 187: 313–19.

Surgery 

Revision Rhytidectomy: Pearls and Pitfalls. Ziai, Kasra, and Babak Azizzadeh. Facial Plastic Surgery: FPS, October.

The Role of Adjuvant Therapy in Duodenal Adenocarcinoma and Intestinal Subtype Ampullary Carcinoma after Curative Resection. Finton, Sarah, Louisa Bolm, Martina Nebbia, Natalie Petruch, Carlos Férnandez-Del Castillo, Motaz Qadan, Keith D. Lillemoe, Ulrich F. Wellner, Marius Distler, Carolin Zimmermann, Jürgen Weitz, Felix Rückert, Nuh N. Rahbari, Christoph Reissfelder, Gennaro Nappo, Tobias Keck, Alessandro Zerbi, and Cristina R. Ferrone. Annals of Surgery, October.

Teprotumumab-Related Adverse Events in Thyroid Eye Disease: A Multi-Center Study. Shah, Shreya A., Linus Amarikwa, Connie M. Sears, Kevin D. Clauss, Raneem D. Rajjoub, Julia Y. Kang, Madhura A. Tamhankar, César A. Briceño, Andrew R. Harrison, Chrysoula C. Dosiou, Kimberly P. Cockerham, Sara T. Wester, Raymond S. Douglas, and Andrea L. Kossler. Ophthalmology, October, S0161-6420(23)00760-1.

Urology

Simultaneous Bladder Drainage via Suprapubic and Urethral Catheters: Which Drains More Completely and Why? Naser-Tavakolian, Aurash, John M. Masterson, Jeremiah Dallmer, Catherine Bresee, Michael Zaliznyak, Hanson Zhao, Sandeep Sandhu, and Maurice M. Garcia. Journal of Surgery and Research 6 (3): 317–22.

Improved Outcomes With Enzalutamide in Biochemically Recurrent Prostate Cancer. Freedland, Stephen J., Murilo de Almeida Luz, Ugo De Giorgi, Martin Gleave, Geoffrey T. Gotto, Christopher M. Pieczonka, Gabriel P. Haas, Choung-Soo Kim, Miguel Ramirez-Backhaus, Antti Rannikko, Jamal Tarazi, Swetha Sridharan, Jennifer Sugg, Yiyun Tang, Ronald F. Tutrone, Balaji Venugopal, Arnauld Villers, Henry H. Woo, Fabian Zohren, and Neal D. Shore. The New England Journal of Medicine 389 (16): 1453–65.