This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Nov. 9-16.

Anesthesiology

Propofol-Based Anesthesia Maintenance and/or Volatile Anesthetics During Intracranial Aneurysm Repair: A Comparative Analysis of Neurological Outcomes. Esmaeeli, Shooka, Negar Motayagheni, Andres Bastos Brenes, Christopher S. Ogilvy, Ajith J. Thomas, Richard Pollard, Lauren K. Buhl, Maxwell B. Baker, Sheshanna Phan, Omron Hassan, Corey R. Fehnel, Matthias Eikermann, Shahzad Shaefi, and Ala Nozari. Journal of Clinical Medicine 12 (21): 6954.

Biomedical Sciences

MicroRNA and Protein Cargos of Human Limbal Epithelial Cell-Derived Exosomes and Their Regulatory Roles in Limbal Stromal Cells of Diabetic and Non-Diabetic Corneas. Verma, Nagendra, Drirh Khare, Adam J. Poe, Cynthia Amador, Sean Ghiam, Andrew Fealy, Shaghaiegh Ebrahimi, Odelia Shadrokh, Xue-Ying Song, Chintda Santiskulvong, Mitra Mastali, Sarah Parker, Aleksandr Stotland, Jennifer E. Van Eyk, Alexander V. Ljubimov, and Mehrnoosh Saghizadeh. Cells 12 (21): 2524.

Effective Connectivity Abnormalities in Lewy Body Disease With Visual Hallucinations. Leodori, Giorgio, Andrea Fabbrini, Antonio Suppa, Marco Mancuso, Sankalp Tikoo, Daniele Belvisi, Antonella Conte, Giovanni Fabbrini, and Alfredo Berardelli. Clinical Neurophysiology, 156 (November): 156–65.

Statement on the Lancet Commission on Medicine, Nazism, and the Holocaust. Chelouche, Tessa, Herwig Czech, Matthew A. Fox, Sabine Hildebrandt, Etienne Lepicard, Astrid Ley, Miriam Offer, Avi Ohry, Shmuel P. Reis, Volker Roelcke, Maike Rotzoll, Carola Sachse, Sari J. Siegel, Michal Šim?nek, Amir Teicher, Kamila Uzarczyk, Anna von Villiez, Hedy S. Wald, and Matthew K. Wynia. Lancet (London, England), November, S0140-6736(23)02461-3.

The Lancet Commission on Medicine, Nazism, and the Holocaust: Historical Evidence, Implications for Today, Teaching for Tomorrow. Czech, Herwig, Sabine Hildebrandt, Shmuel P. Reis, Tessa Chelouche, Matthew Fox, Esteban González-López, Etienne Lepicard, Astrid Ley, Miriam Offer, Avi Ohry, Maike Rotzoll, Carola Sachse, Sari J. Siegel, Michal Šim?nek, Amir Teicher, Kamila Uzarczyk, Anna von Villiez, Hedy S. Wald, Matthew K. Wynia, and Volker Roelcke. Lancet (London, England), November, S0140-6736(23)01845-7.

Cardiac Surgery

Introduction of Comprehensive Longitudinal Outcomes to the STS National Databases. Bowdish, Michael E. The Annals of Thoracic Surgery, November, S0003-4975(23)01158-X.

Cardiology

Association of Atrial Fibrillation With Stroke and Dementia Accounting for Left Atrial Function and Size. Zhang, Michael J., Yuekai Ji, Wendy Wang, Faye L. Norby, Romil Parikh, Anne A. Eaton, Riccardo M. Inciardi, Alvaro Alonso, Elsayed Z. Soliman, Thomas H. Mosley, Michelle C. Johansen, Rebecca F. Gottesman, Amil M. Shah, Scott D. Solomon, and Lin Yee Chen. JACC. Advances 2 (5): 100408.

One-Year Outcomes From the CLASP IID Randomized Trial for Degenerative Mitral Regurgitation. Zahr, Firas, Robert L. Smith, Linda D. Gillam, Scott Chadderdon, Raj Makkar, Ralph Stephan von Bardeleben, Tobias Friedrich Ruf, Robert M. Kipperman, Andrew N. Rassi, Molly Szerlip, Scott Goldman, Ignacio Inglessis-Azuaje, Pradeep Yadav, Philipp Lurz, Charles J. Davidson, Mubashir Mumtaz, Hemal Gada, Saibal Kar, Susheel K. Kodali, Roger Laham, William Hiesinger, Neil P. Fam, Mirjam Keßler, William W. O’Neill, Brian Whisenant, Chad Kliger, Samir Kapadia, Volker Rudolph, Joseph Choo, James Hermiller, Michael A. Morse, Niklas Schofer, Sameer Gafoor, Azeem Latib, Paul Mahoney, Tsuyoshi Kaneko, Pinak B. Shah, John A. Riddick, Kamran I. Muhammad, Peter Boekstegers, Matthew J. Price, Fabien Praz, Konstantinos Koulogiannis, Leo Marcoff, Jörg Hausleiter, D. Scott Lim, and CLASP IID Pivotal Trial Investigators. JACC. Cardiovascular Interventions, October, S1936-8798(23)01358-4.

Revascularization Strategies for Multivessel Coronary Artery Disease Based on Sex and Age. Sulaiman, Samian, Lamia Harik, C. Noel Bairey Merz, Stephen E. Fremes, Ruth Masterson Creber, Lisa Q. Rong, Mohamad Alkhouli, and Mario Gaudino. European Journal of Cardio-Thoracic Surgery, 64 (5): ezad374.

Peripartum Cardiomyopathy Delivery Hospitalization and Postpartum Readmission Trends, Risk Factors, and Outcomes. Azad, Hooman, Timothy Wen, Natalie A. Bello, Whitney A. Booker, Stephanie Purisch, Mary E. D’Alton, and Alexander M. Friedman. Pregnancy Hypertension 34 (November): 116–23.

Rationale and Design of the CONFIRM2 (Quantitative COroNary CT Angiography Evaluation for Evaluation of Clinical Outcomes: An InteRnational, Multicenter Registry) Study. Rosendael, Alexander R. van, Tami Crabtree, Jeroen J. Bax, Rine Nakanishi, Saima Mushtaq, Gianluca Pontone, Daniele Andreini, Ronny R. Buechel, Christoph Gräni, Gudrun Feuchtner, Toral R. Patel, Andrew D. Choi, Mouaz Al-Mallah, Faisal Nabi, Ronald P. Karlsberg, Carlos E. Rochitte, Mirvat Alasnag, Ashraf Hamdan, Filippo Cademartiri, Hugo Marques, Dinesh Kalra, David M. German, Himanshu Gupta, Martin Hadamitzky, Roderick C. Deaño, Omar Khalique, Paul Knaapen, Udo Hoffmann, James Earls, James K. Min, Ibrahim Danad, and CONFIRM 2 investigators. Journal of Cardiovascular Computed Tomography, November, S1934-5925(23)00454-9.

Digital Tool-Assisted Hospitalization Detection in the Tailored Antiplatelet Initiation to Lessen Outcomes Due to Decreased Clopidogrel Response After Percutaneous Coronary Intervention Study Compared to Traditional Site-Coordinator Ascertainment: Intervention Study. Avram, Robert, Julia Byrne, Derek So, Erin Iturriaga, Ryan Lennon, Vishakantha Murthy, Nancy Geller, Shaun Goodman, Charanjit Rihal, Yves Rosenberg, Kent Bailey, Michael Farkouh, Malcolm Bell, Charles Cagin, Ivan Chavez, Mohammad El-Hajjar, Wilson Ginete, Amir Lerman, Justin Levisay, Kevin Marzo, Tamim Nazif, Jean-Francois Tanguay, Mark Pletcher, Gregory M. Marcus, Naveen L. Pereira, and Jeffrey Olgin. Journal of Medical Internet Research 25 (November): e47475.

Diverse Biological Functions of the Renin-Angiotensin System. Rao, Adithi, Shabir A. Bhat, Tomohiro Shibata, Jorge F. Giani, Florian Rader, Bernstein E. Kenneth, and Zakir Khan. Medicinal Research Reviews, November.

Dynamic ECG Changes Are a Novel Risk Marker for Sudden Cardiac Death. Pham, H. N., L. Holmstrom, H. Chugh, A. Uy-Evanado, K. Nakamura, Z. Zhang, A. Salvucci, J. Jui, K. Reinier, and S. S. Chugh. European Heart Journal, November, ehad770.

Non-Dipping Blood Pressure or Nocturnal Hypertension: Does One Matter More? Tang, Amber, Eugene Yang, and Joseph E. Ebinger. Current Hypertension Reports, November.

Heart-Liver Axis Implications of the New Steatotic Liver Disease Nomenclature. Li, Pengfei, Hongwei Ji, and Susan Cheng. The Lancet. Gastroenterology & Hepatology 8 (12): 1071–72.

Medicine

Africa Guidelines for Hepatocellular Carcinoma Buildup Process. Abou-Alfa, Ghassan K., Mary Afihene, Marinela Capanu, Yuelin Li, Joanne F. Chou, Akwi Asombang, Olusegun Isaac Alatise, Adda Bounedjar, Lina Cunha, Hailemichael Desalegn Mekonnen, Papa Saloum Diop, Reda Elwakil, Mahamat Moussa Ali, Ntokozo Ndlovu, Jerry Ndumbalo, Precious Takondwa Makondi, Christian Tzeuton, Tiago Biachi de Castria, Adwoa Afrakoma Agyei-Nkansah, Fiyinfolu Balogun, Alain Bougouma, Blaise Irénée Atipo Ibara, Eduard Jonas, Stephen Kimani, Peter Kingham, Reshad Kurrimbukus, Nazik Hammad, Mona Fouad, Noha El Baghdady, Eloumou Bagnaka Servais Albert Fiacre, Vikash Sewram, C. Wendy Spearman, Ju Dong Yang, Lewis R. Roberts, and Ashraf O. Abdelaziz. JCO Global Oncology 9 (September): e2300159.

The Effect of Hormonal Secretion on Survival in Adrenocortical Carcinoma: A Multi-Center Study. Sada, Alaa, Trenton R. Foster, Ruaa Al-Ward, Sahar Sawani, HElaine Charchar, Reza Pishdad, Anat Ben-Shlomo, Benzon M. Dy, Melanie L. Lyden, Emily Bergsland, Sina Jasim, Nitya Raj, Jessica B. Shank, Oksana Hamidi, Amir H. Hamrahian, José L. Chambô, Victor Srougi, Maria Cbv Fragoso, Paul H. Graham, Mouhammed Amir Habra, Irina Bancos, and Travis J. McKenzie. Surgery, November, S0039-6060(23)00679-7.

Changes in Site of Death Among Older Adults Without a COVID-19 Diagnosis During the COVID-19 Pandemic. Gotanda, Hiroshi, Jessica J. Zhang, Debra Saliba, Haiyong Xu, and Yusuke Tsugawa. Journal of General Internal Medicine, November.

Deprescribing Medications Among Patients With Multiple Prescribers: A Socioecological Model. Silva Almodóvar, Armando, Michelle S. Keller, Jiha Lee, Hemalkumar B. Mehta, Veena Manja, Thanh Phuong Pham Nguyen, Juliessa M. Pavon, Samuel W. Terman, Daniel Hoyle, Amanda S. Mixon, and Amy M. Linsky. Journal of the American Geriatrics Society, November.

Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19. Jensen, Tomas O., Greg A. Grandits, Mamta K. Jain, Thomas A. Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A. Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V. Baker, Peter Chen, Robin L. Dewar, Anna L. Goodman, Timothy J. Hatlen, Helene C. Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G. Leshnower, David Looney, Charalampos D. Moschopoulos, Henry Mugerwa, Daniel D. Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M. Tauseef Rehman, Adam Rupert, Randy A. Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R. Ko, and ACTIV-3/TICO Study Group. The Journal of Infectious Diseases, November, jiad446.

ENTERPRET: A Randomized Controlled Trial of Vedolizumab Dose Optimization in Patients With Ulcerative Colitis Who Have Early Nonresponse. Jairath, Vipul, Andres Yarur, Mark T. Osterman, Alexandra James, Diane Balma, Shailly Mehrotra, Lili Yang, Vijay Yajnik, and Rana M. Qasim Khan. Clinical Gastroenterology and Hepatology, November, S1542-3565(23)00912-6.

Reply to He et Al. Yarur, Andres J., and Parakkal Deepak. Gastroenterology, November, S0016-5085(23)05234-4.

Skeletal Muscle TFEB Signaling Promotes Central Nervous System Function and Reduces Neuroinflammation During Aging and Neurodegenerative Disease. Matthews, Ian, Allison Birnbaum, Anastasia Gromova, Amy W. Huang, Kailin Liu, Eleanor A. Liu, Kristen Coutinho, Megan McGraw, Dalton C. Patterson, Macy T. Banks, Amber C. Nobles, Nhat Nguyen, Gennifer E. Merrihew, Lu Wang, Eric Baeuerle, Elizabeth Fernandez, Nicolas Musi, Michael J. MacCoss, Helen C. Miranda, Albert R. La Spada, and Constanza J. Cortes. Cell Reports 42 (11): 113436.

The Safety, Tolerability, Pharmacokinetics and Clinical Efficacy of the NLRX1 Agonist NX-13 in Active Ulcerative Colitis: Results of a Phase 1b Study. Verstockt, Bram, Severine Vermeire, Laurent Peyrin-Biroulet, Rebecca Mosig, Brian G. Feagan, Jean-Frederic Colombel, Britta Siegmund, Florian Rieder, Stefan Schreiber, Andres Yarur, Remo Panaccione, Marla Dubinsky, Simon Lichtiger, Fabio Cataldi, and Silvio Danese. Journal of Crohn’s & Colitis, November, jjad192.

Patients’ Preferences for Fracture Risk Communication: The Risk Communication in Osteoporosis (RICO) Study. Beaudart, Charlotte, Mitali Sharma, Patricia Clark, Saeko Fujiwara, Jonathan D. Adachi, Osvaldo D. Messina, Suzanne N. Morin, Lynn A. Kohlmeier, Caroline B. Sangan, Xavier Nogues, Griselda Adriana Cruz-Priego, Andrea Cavallo, Fiona Cooper, Jamie Grier, Carolyn Leckie, Diana Montiel-Ojeda, Alexandra Papaioannou, Nele Raskin, Leonardo Yurquina, Michelle Wall, Olivier Bruyère, Annelies Boonen, Elaine Dennison, Nicholas C. Harvey, John A. Kanis, Jean-François Kaux, E. Michael Lewiecki, Oscar Lopez-Borbon, Zoé Paskins, Jean-Yves Reginster, Stuart Silverman, and Mickaël Hiligsmann. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, November.

Disseminating Steatotic Liver Disease Patient Education: The Emerging Role of Large Language Models. Yeo, Yee Hui, and Ju Dong Yang. Clinical and Molecular Hepatology, November.

The Role of Admixture in the Rare Variant Contribution to Inflammatory Bowel Disease. Astore, Courtney, Shivam Sharma, Sini Nagpal, NIDDK IBD Genetics Consortium, David J. Cutler, John D. Rioux, Judy H. Cho, Dermot P. B. McGovern, Steven R. Brant, Subra Kugathasan, I. King Jordan, and Greg Gibson. Genome Medicine 15 (1): 97.

A Prospective Study Examining Audiometry Outcomes Following Teprotumumab Treatment for Thyroid Eye Disease. Douglas, Raymond D., Emanuil Parunakian, Joseph Tolentino, Emil Malkhasyan, June Geng, Michele Sherman, and Shoaib Ugradar. Thyroid, November.

Neurosurgery

Benefits of Sharing Neurophysiology Data From the BRAIN Initiative Research Opportunities in Humans Consortium. Rahimzadeh, Vasiliki, Kathryn Maxson Jones, Mary A. Majumder, Michael J. Kahana, Ueli Rutishauser, Ziv M. Williams, Sydney S. Cash, Angelique C. Paulk, Jie Zheng, Michael S. Beauchamp, Jennifer L. Collinger, Nader Pouratian, Amy L. McGuire, Sameer A. Sheth, and NIH Research Opportunities in Humans (ROH) Consortium. Neuron, November, S0896-6273(23)00717-1.

Endoscopic Endonasal Transclival Clipping of a Cerebellar Arteriovenous Malformation Feeding Vessel and Associated Aneurysm; a 2D Operative Video. Nisson, Peyton L., Ryan Palsma, Zachary R. Barnard, Wouter I. Schievink, and Adam N. Mamelak. Journal of Clinical Neuroscience, 118 (November): 161–62.

OBGYN

Clinical Implications of a Cesarean Scar Pregnancy Sonographic Evaluation and Reporting System. Meyer, Raanan, Lior Friedrich, Roni Plaschkes, Shlomi Toussia-Cohen, Gabriel Levin, Tal Weissbach, Eran Kassif, and Roy Mashiach. European Journal of Obstetrics, Gynecology, and Reproductive Biology 291 (November): 247–51.

‘Authors Reply’ Racial and Gender Representation Trends Among National Obstetrics and Gynecology Society Leadership. Hamilton, Kacey M., Stacey A. Scheib, and Mireille D. Truong. Journal of Minimally Invasive Gynecology, November, S1553-4650(23)00957-3.

Sustainability in Obstetrics and Gynecology. Wright, Kelly N., Alexandra I. Melnyk, Jordan Emont, and Jane Van Dis. Obstetrics and Gynecology, November.

Cancer-Related Financial Hardship Screening as Part of Practice Transformation. Williams, Courtney P., Margaret I. Liang, Gabrielle B. Rocque, Risha Gidwani, Nicole E. Caston, and Maria Pisu. Medical Care 61 (12 Suppl 2): S116–21.

Orthopaedics

Management of Hand and Wrist Injuries in NCAA Division I Football Players From a Single Institution: Factors Associated With Epidemiology, Surgical Intervention, and Return to Play. Bougioukli, Sofia, Ioanna K. Bolia, Cory K. Mayfield, Luke T. Nicholson, Alexander E. Weber, Bryan S. Bashrum, Russell Romano, James E. Tibone, Steven Shin, and Seth C. Gamradt. Orthopaedic Journal of Sports Medicine 11 (11): 23259671231188969.

Complications Have Not Improved With Newer Generation Robots. Farivar, Daniel, Terrence T. Kim, Christopher A. Sy, Eli M. Baron, Edward K. Nomoto, Corey T. Walker, and David L. Skaggs. Global Spine Journal, November, 21925682231216081.

Pediatrics 

Children Are Not Small Adults: Similarities and Differences in Renal Transplantation Between Adults and Pediatrics. Puliyanda, Dechu, Zibya Barday, Zunaid Barday, Andrew Freedman, Tsuyoshi Todo, Allen Kuang Chung Chen, and Bianca Davidson. Seminars in Nephrology, November, 151442.

2023 American Heart Association and American Academy of Pediatrics Focused Update on Neonatal Resuscitation: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Yamada, Nicole K., Edgardo Szyld, Marya L. Strand, Emer Finan, Jessica L. Illuzzi, Beena D. Kamath-Rayne, Vishal S. Kapadia, Susan Niermeyer, Georg M. Schmölzer, Amanda Williams, Gary M. Weiner, Myra H. Wyckoff, and Henry C. Lee. Pediatrics, November.

Surgery

Androgen Receptor in Breast Cancer and Its Clinical Implication. Hackbart, Hannah, Xiaojiang Cui, and Jin Sun Lee. Translational Breast Cancer Research: A Journal Focusing on Translational Research in Breast Cancer 4 (October): 30.

Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer: Too Much of a Good Thing? DiPeri, Timothy P., Jun Gong, and Miguel Burch. Journal of Gastrointestinal Oncology 14 (5): 2287–89.

Masculinizing Hormone Therapy Effect on Breast Tissue: Changes in Estrogen and Androgen Receptors in Transgender Female-to-Male Mastectomies. Chaum, Manita, Sara Grossi, Jiaxi Chen, Vivian Hu, Edward Ray, Armando Giuliano, and Shikha Bose. Breast (Edinburgh, Scotland) 72 (November): 103596.

Implications of High Tumor Burden on Chimeric Antigen Receptor T-Cell Immunotherapy: A Review. Ventin, Marco, Giulia Cattaneo, Luke Maggs, Shahrzad Arya, Xinhui Wang, and Cristina R. Ferrone. JAMA Oncology, November.

A Prospective Study Examining Audiometry Outcomes Following Teprotumumab Treatment for Thyroid Eye Disease. Douglas, Raymond D., Emanuil Parunakian, Joseph Tolentino, Emil Malkhasyan, June Geng, Michele Sherman, and Shoaib Ugradar. Thyroid, November.

Anti-CCL2 Antibody Combined With Etoposide Prolongs Survival in a Minimal Residual Disease Mouse Model of Neuroblastoma. Lascano, Danny, Michael J. Zobel, William G. Lee, Stephanie Y. Chen, Abigail Zamora, Grace E. Asuelime, So Yung Choi, Antonios Chronopoulos, Shahab Asgharzadeh, Araz Marachelian, Jinseok Park, Michael A. Sheard, and Eugene S. Kim. Scientific Reports 13 (1): 19915.

Current Use of Immunosuppression in Liver Transplantation. Adjei, Michie, and Irene K. Kim. The Surgical Clinics of North America 104 (1): 11–25.

Urology

Are Higher Follicle-Stimulating Hormone Levels Before Androgen Deprivation Therapy for Prostate Cancer Associated With Oncological and Cardiac Outcomes and Overall Survival? A Population-Level Analysis. Dymanus, Kyle, Nadine A. Friedrich, Lauren E. Howard, Taofik Oyekunle, Amanda M. De Hoedt, Artak Labadzhyan, Thomas Polascik, Zachary Klaassen, and Stephen J. Freedland. Translational Andrology and Urology 12 (10): 1540–49.

Genetic and Biological Drivers of Prostate Cancer Disparities in Black Men. Gong, Jun, Daniel M. Kim, Michael R. Freeman, Hyung Kim, Leigh Ellis, Bethany Smith, Dan Theodorescu, Edwin Posadas, Robert Figlin, Neil Bhowmick, and Stephen J. Freedland. Nature Reviews. Urology, November.

A US Real-World Study of Treatment Patterns and Outcomes in Localized or Locally Advanced Prostate Cancer Patients. Freedland, Stephen J., Sandhya Nair, Xiwu Lin, Lawrence Karsh, Christopher Pieczonka, Ravi Potluri, Sabine D. Brookman-May, Suneel D. Mundle, Sarah Fleming, and Neeraj Agarwal. World Journal of Urology, November.

Association of Molecular Subtypes With Pathologic Response, PFS and OS in a Phase II Study of COXEN With Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer. Lerner, Seth P., David J. McConkey, Catherine M. Tangen, Joshua J. Meeks, Thomas W. Flaig, X. Hua, Siamak Daneshmand, Ajjai Shivaram Alva, M. Scott Lucia, Dan Theodorescu, Amir Goldkorn, Matthew I. Milowsky, W. Choi, Rick Bangs, Daniel L. Gustafson, Melissa Plets, and Ian M. Thompson. Clinical Cancer Research, November.

Enzalutamide or Placebo Plus Leuprolide Acetate and Enzalutamide Monotherapy in Men With High-Risk Biochemically Recurrent Prostate Cancer and Prior Radiotherapy: EMBARK Subgroup Analysis. Sridharan, S., N. Shore, B. Venugopal, M. Gleave, U. De Giorgi, Y. Tang, G. P. Haas, M. Rosales, F. Zohren, and S. J. Freedland. International Journal of Radiation Oncology Biology Physics 117 (4): e4–5.

A Glance at the Present and Future of Artificial Intelligence in Urology. Hung, Andrew J. The Urologic Clinics of North America 51 (1): xiii.