This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. Nov. 2-9.

Anesthesiology

Left Atrial Appendage Closure: A Narrative Review. Nagasaka, Takashi, and Mamoo Nakamura. Cardiology and Therapy, November.

Biomedical Sciences 

Myeloid Cell ACE Shapes Cellular Metabolism and Function in PCSK-9 Induced Atherosclerosis. Cao, DuoYao, Suguru Saito, LiMin Xu, Wei Fan, Xiaomo Li, Faizan Ahmed, Predrag Jovanovic, Tomohiro Shibata, Mingtian Che, Ellen A. Bernstein, Jorge Gianni, Ajit S. Divakaruni, Derick Okwan-Duodu, Zakir Khan, Celine E. Riera, Fanfan Chen, and Kenneth E. Bernstein. Frontiers in Immunology 14: 1278383.

Impaired Gut Microbiota-Mediated Short-Chain Fatty Acid Production Precedes Morbidity and Mortality in People With HIV. Sereti, Irini, Myrthe L. Verburgh, Jacob Gifford, Alice Lo, Anders Boyd, Eveline Verheij, Aswin Verhoeven, Ferdinand W. N. M. Wit, Maarten F. Schim van der Loeff, Martin Giera, Neeltje A. Kootstra, Peter Reiss, and Ivan Vujkovic-Cvijin. Cell Reports, October, 113336.

Aortic Valve Perivascular Adipose Tissue Computed Tomography Attenuation in Patients With Aortic Stenosis. Botezatu, Simona B., Xinming Yu, Mohammed N. Meah, Michelle C. Williams, Damini Dey, David E. Newby, Evangelos Tzolos, and Marc R. Dweck. Heart (British Cardiac Society), November, heartjnl-2023-323217.

Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo. Read, Martin L., Katie Brookes, Ling Zha, Selvambigai Manivannan, Jana Kim, Merve Kocbiyik, Alice Fletcher, Caroline M. Gorvin, George Firth, Gilbert O. Fruhwirth, Juan P. Nicola, Sissy Jhiang, Matthew D. Ringel, Moray J. Campbell, Kavitha Sunassee, Philip J. Blower, Kristien Boelaert, Hannah R. Nieto, Vicki E. Smith, and Christopher J. McCabe. Clinical Cancer Research, November.

Subclinical Atherosclerosis on Chest Computed Tomography and Mortality in Young Patients With Severe Hypercholesterolemia. Piña, Pamela, Carol Fernandez, Daniel Lorenzatti, Francesco Castagna, Jeremy Miles, Toshiki Kuno, Andrea Scotti, Javier Arce, Carlos A. Gongora, Aldo L. Schenone, Matthew J. Budoff, Khurram Nasir, Ron Blankstein, Michael J. Blaha, Damini Dey, Daniel S. Berman, Jeffrey M. Levsky, Salim S. Virani, Mario J. Garcia, and Leandro Slipczuk. Progress in Cardiovascular Diseases, November, S0033-0620(23)00113-5.

Inequities in Colorectal and Breast Cancer Screening: At the Intersection of Race/Ethnicity, Sexuality, and Gender. Lin, Emmeline, Patrycja Sleboda, Bobbie J. Rimel, and Geetanjali D. Datta. SSM - Population Health 24 (December): 101540.

Cardiac Surgery

Prospective Study of Risk Factors for Postoperative Atrial Fibrillation After Cardiac Surgery. Bowdish, Michael E., Emilia Bagiella, Gennaro Giustino, Pavan Atluri, John H. Alexander, Vinod H. Thourani, James S. Gammie, Joseph J. DeRose, Wendy C. Taddei-Peters, Neal O. Jeffries, Patrick T. O’Gara, Alan J. Moskowitz, Marc Gillinov, Annetine C. Gelijns, Gorav Ailawadi, and Cardiothoracic Surgical Trials Network. The Journal of Surgical Research 294 (November): 262–68.

Sex-Specific Morphometric Analysis of Ascending Aorta and Aortic Arch for Planning Thoracic Endovascular Aortic Repair: A Retrospective Cohort Study. Katsarou, Maria, Tim J. Mandigers, Marton Berczeli, M. Mujeeb Zubair, Viony M. Belvroy, Daniele Bissacco, Joost A. van Herwaarden, Santi Trimarchi, and Jean Bismuth. Journal of Endovascular, November, 15266028231210228.

Cardiology

Thymus Alterations and Susceptibility to Immune Checkpoint Inhibitor Myocarditis. Fenioux, Charlotte, Baptiste Abbar, Samia Boussouar, Marie Bretagne, John R. Power, Javid J. Moslehi, Paul Gougis, Damien Amelin, Agnès Dechartres, Lorenz H. Lehmann, Pierre-Yves Courand, Jennifer Cautela, Joachim Alexandre, Adrien Procureur, Antoine Rozes, Sarah Leonard-Louis, Juan Qin, International ICI-Myocarditis Registry, Rémi Cheynier, Benedicte Charmeteau-De Muylder, Alban Redheuil, Florence Tubach, Jacques Cadranel, Audrey Milon, Stéphane Ederhy, Thomas Similoswki, Douglas B. Johnson, Ian Pizzo, Toniemarie Catalan, Olivier Benveniste, Salim S. Hayek, Yves Allenbach, Michelle Rosenzwajg, Charles Dolladille, and Joe-Elie Salem. Nature Medicine, October.

The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents With the Fontan Circulation. Edelson, Jonathan, Victor Zak, David Goldberg, Greg Fleming, Andrew Mackie, Jyoti K. Patel, Matthew Files, Tacy Downing, Marc Richmond, Ben Acheampong, Mark Cartoski, Jon Detterich, Brian McCrindle, Kimberly McHugh, Jesse E. Hansen, Jonathan Wagner, Michael Di Maria, Angela Weingarten, Todd Nowlen, Ja Kyoung Yoon, Gi Beom Kim, Richard Williams, Robert Whitehill, Edward Kirkpatrick, Suellen Yin, Peter Ermis, Adam M. Lubert, Mario Stylianou, D’Andrea Freemon, Chenwei Hu, Olukayode D. Garuba, Peter Frommelt, Bryan H. Goldstein, Stephen Paridon, Ruchira Garg, and Pediatric Heart Network Investigators. The American Journal of Cardiology, October, S0002-9149(23)01135-9.

Safety of Coronary Provocative Testing With Intracoronary Ergonovine. Takahashi, Tatsunori, Bruce A. Samuels, Janet Wei, Edward T. Ha, Meggie Chan, Manish A. Parikh, and Yuhei Kobayashi. Cardiovascular Revascularization Medicine: Including Molecular Interventions, October, S1553-8389(23)00863-1.

Quantitative Analysis of Acetyl-CoA, Malonyl-CoA, and Succinyl-CoA in Myocytes. Tan, Lin, Sara A. Martinez, Philip L. Lorenzi, and Anja Karlstaedt. Journal of the American Society for Mass Spectrometry 34 (11): 2567–74.

Transfemoral Tricuspid Valve Replacement and One-Year Outcomes: The TRISCEND Study. Kodali, Susheel, Rebecca T. Hahn, Raj Makkar, Moody Makar, Charles J. Davidson, Jyothy J. Puthumana, Firas Zahr, Scott Chadderdon, Neil Fam, Geraldine Ong, Pradeep Yadav, Vinod Thourani, Mani A. Vannan, William W. O’Neill, Dee Dee Wang, Didier Tchétché, Nicolas Dumonteil, Laurent Bonfils, Laurent Lepage, Robert Smith, Paul A. Grayburn, Rahul P. Sharma, Christiane Haeffele, Vasilis Babaliaros, Patrick T. Gleason, Sammy Elmariah, Ignacio Inglessis-Azuaje, Jonathan Passeri, Howard C. Herrmann, Frank E. Silvestry, Scott Lim, Dale Fowler, John G. Webb, Robert Moss, Thomas Modine, Stephane Lafitte, Azeem Latib, Edwin Ho, Ythan Goldberg, Pinak Shah, Charles Nyman, Josep Rodés-Cabau, Elisabeth Bédard, Nicolas Brugger, Anna Sannino, Michael J. Mack, Martin B. Leon, Stephan Windecker, and TRISCEND study investigators. European Heart Journal, November, ehad667.

Gender Differences in Workplace Violence Against Physicians and Nurses in Latin America: A Survey From the Interamerican Society of Cardiology. Parodi, J. B., L. M. Burgos, S. Garcia-Zamora, K. Liblik, L. Pulido, S. Gupta, C. Saldarriaga, A. C. Puente-Barragan, P. Morejón-Barragán, E. Alexanderson-Rosas, A. Sosa-Liprandi, F. Botto, M. I. Sosa-Liprandi, R. Lopez-Santi, G. Vazquez, M. Gulati, and A. Baranchuk. Public Health 225 (November): 127–32.

Effect of Ascending Aortic Curvature on Flow in the Sinus and Neo-Sinus Following TAVR: A Patient-Specific Study. Kim, Jae Hyun, Vahid Sadri, Huang Chen, Sanchita Bhat, Keshav Kohli, Raj Makkar, Vasilis C. Babaliaros, Rahul P. Sharma, and Ajit P. Yoganathan. Annals of Biomedical Engineering, November.

Computational Biomedicine

Quantifying and Correcting Bias Due to Outcome Dependent Self-Reported Weights in Longitudinal Study of Weight Loss Interventions. Tong, Jiayi, Rui Duan, Ruowang Li, Chongliang Luo, Jason H. Moore, Jingsan Zhu, Gary D. Foster, Kevin G. Volpp, William S. Yancy, Pamela A. Shaw, and Yong Chen. Scientific Reports 13 (1): 19078.

Medicine

Elderly Rats Fed With a High-Fat High-Sucrose Diet Developed Sex-Dependent Metabolic Syndrome Regardless of Long-Term Metformin and Liraglutide Treatment. Ivi?, Vedrana, Milorad Zjali?, Senka Blažeti?, Matija Fenrich, Irena Labak, Rudolf Scitovski, Kálmán Ferenc Sz?cs, Eszter Ducza, Tamás Tábi, Fruzsina Bagamery, Éva Szök?, Rosemary Vukovi?, Alen Ron?evi?, Dario Mandi?, Željko Debeljak, Monika Berecki, Marta Balog, Adrienn Seres-Bokor, Anita Sztojkov-Ivanov, Judit Hajagos-Tóth, Sre?ko Gajovi?, Alen Imširovi?, Marina Bakula, Solomiia Mahiiovych, Robert Gaspar, Sandor G. Vari, and Marija Heffer. Frontiers in Endocrinology 14: 1181064.

Oral Chronic Graft-Versus-Host Disease in Post-Hematopoietic Stem Cell Transplant Patients Following SARS-CoV-2 Vaccination: Case Reports. Epstein, Joel B., Raymond S. Hernandez, Ryotaro Nakamura, Susan E. Yost, and Haris Ali. Case Reports in Oncology 16 (1): 1287–92.

Risk Factors for Meibomian Gland Disease Assessed by Meibography. Kim, Christine K., Steven Carter, Cinthia Kim, Tara Shooshani, Urmi Mehta, Kailey Marshall, Ryan G. Smith, Alexander Knezevic, Kavita Rao, Olivia L. Lee, and Marjan Farid. Clinical Ophthalmology (Auckland, N.Z.) 17: 3331–39.

Rectal Urgency Among Patients With Ulcerative Colitis or Crohn’s Disease: Analyses From a Global Survey. Ha, Christina, April N. Naegeli, Rina Lukanova, Mingyang Shan, Rosie Wild, Fritha Hennessy, Uma Jyothi Kommoju, Alison Potts Bleakman, and Theresa Hunter Gibble. Crohn’s & Colitis 360 5 (4): otad052.

Super-Enhancer Trapping by the Nuclear Pore via Intrinsically Disordered Regions of Proteins in Squamous Cell Carcinoma Cells. Hazawa, Masaharu, Dini Kurnia Ikliptikawati, Yuki Iwashima, De-Chen Lin, Yuan Jiang, Yujia Qiu, Kei Makiyama, Koki Matsumoto, Akiko Kobayashi, Goro Nishide, Lim Keesiang, Hironori Yoshino, Toshinari Minamoto, Takeshi Suzuki, Isao Kobayashi, Makiko Meguro-Horike, Yan-Yi Jiang, Takumi Nishiuchi, Hiroki Konno, H. Phillip Koeffler, Kazuyoshi Hosomichi, Atsushi Tajima, Shin-Ichi Horike, and Richard W. Wong. Cell Chemical Biology, October, S2451-9456(23)00366-5.

Beyond the Checkpoint: Severe Axitinib-Induced Liver Injury. Yeo, Yee Hui, Walid Ayoub, Ju Dong Yang, Alexander Kuo, and Hirsh D. Trivedi. ACG Case Reports Journal 10 (11): e01177.

After DNA Damage, AREG-Ular Niche It’s Not. Chute, John P. Blood 142 (18): 1502–4.

Consensus on Criteria for Acromegaly Diagnosis and Remission. Giustina, Andrea, Nienke Biermasz, Felipe F. Casanueva, Maria Fleseriu, Pietro Mortini, Christian Strasburger, A. J. van der Lely, John Wass, Shlomo Melmed, and Acromegaly Consensus Group. Pituitary, November.

CT Attenuation Correction Improves Quantitative Risk Prediction by Cardiac SPECT in Obese Patients. Feher, Attila, Konrad Pieszko, Aakash Shanbhag, Mark Lemley, Bryan Bednarski, Robert J. H. Miller, Cathleen Huang, Leonidas Miras, Yi-Hwa Liu, Albert J. Sinusas, Piotr J. Slomka, and Edward J. Miller. European Journal of Nuclear Medicine and Molecular Imaging, November.

Excess Pancreatic Cancer Risk Due to Smoking and Modifying Effect of Quitting Smoking: The Multiethnic Cohort Study. Bogumil, David, Daniel Stram, Dale L. Preston, Stephen J. Pandol, Anna H. Wu, Roberta McKean-Cowdin, David V. Conti, and Veronica Wendy Setiawan. Cancer Causes & Control: CCC, November.

Deconstruction of Rheumatoid Arthritis Synovium Defines Inflammatory Subtypes. Zhang, Fan, Anna Helena Jonsson, Aparna Nathan, Nghia Millard, Michelle Curtis, Qian Xiao, Maria Gutierrez-Arcelus, William Apruzzese, Gerald F. M. Watts, Dana Weisenfeld, Saba Nayar, Javier Rangel-Moreno, Soumya Raychaudhuri, et al. Nature, November.

Treatment Rates and Factors Associated With Direct-Acting Antiviral Therapy for Insured Patients With Hepatitis C-Related Hepatocellular Carcinoma - A Real-World Nationwide Study. Kam, Leslie Y., Yee Hui Yeo, Fanpu Ji, Linda Henry, Ramsey Cheung, and Mindie H. Nguyen. Alimentary Pharmacology & Therapeutics, November.

Neurology

Alerting Providers to Hospitalized Persons With Dementia Using the Electronic Health Record. Tan, Zaldy S., Nabeel Qureshi, Pamela Roberts, Augustine Guinto, Cameron Escovedo, Phong Chung, Erica Spivack, Mary Nasmyth, Sarah Kremen, and Nancy L. Sicotte. Journal of the American Geriatrics Society, November.

Neurosurgery

Meningioma Transformation to Glioblastoma Following Stereotactic Radiosurgery: A Case Report and Review of the Literature. Boyke, Andre Everett, Michelot Michel, Catherine Michelle Garcia, Serguei I. Bannykh, Julie Lynn Chan, and Keith L. Black. Surgical Neurology International 14: 364.

Retina Pathology as a Target for Biomarkers for Alzheimer’s Disease: Current Status, Ophthalmopathological Background, Challenges, and Future Directions. Alber, Jessica, Femke Bouwman, Jurre den Haan, Robert A. Rissman, Lies De Groef, Maya Koronyo-Hamaoui, Imre Lengyel, Dietmar Rudolf Thal, and Alzheimer’s Association ISTAART The Eye as a Biomarker for AD Professional Interest Area. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, November.

A Uniform Human Multimodal Dataset for Emotion Perception and Judgment. Sun, Sai, Runnan Cao, Ueli Rutishauser, Rongjun Yu, and Shuo Wang. Scientific Data 10 (1): 773.

OBGYN

Vaginal Cuff Dehiscence in Transgender Patients After Minimally Invasive Hysterectomy. O’Connor, Reed M., Marla E. Scott, and B. J. Rimel. Journal of Minimally Invasive Gynecology, November, S1553-4650(23)00928-7.

Pathology

The Banff 2022 Kidney Meeting Work Plan: Data-Driven Refinement of the Banff Classification for Renal Allografts. Roufosse, Candice, Maarten Naesens, Mark Haas, Carmen Lefaucheur, Roslyn B. Mannon, Marjan Afrouzian, Nada Alachkar, Olivier Aubert, Serena M. Bagnasco, Ibrahim Batal, Chris O. C. Bellamy, Verena Broecker, Michael Mengel, et al. American Journal of Transplantation, November, S1600-6135(23)00855-9.

Pediatrics

The Need for Simulation-Based Procedural Skills Training to Address Proposed Changes in Accreditation Council for Graduate Medical Education Requirements for Pediatric Residency Programs. Nawathe, Pooja A., David O. Kessler, Gregory Yurasek, Taylor L. Sawyer, Louis P. Halamek, Kimberly Stone, Geethanjali Ramachandra, Tensing Maa, Nancy Tofil, Cara Doughty, Sujatha Thyagarajan, Marjorie L. White, Rebekah Damazo, and Aaron Calhoun. Simulation in Healthcare: Journal of the Society for Simulation in Healthcare, November.

Radiation Oncology

Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis. Kombe, Arnaud John Kombe, Samira Zoa-Assoumou, Guy-Armel Bounda, Fleury-Augustin Nsole-Biteghe, Tengchuan Jin, and Abdou Azaque Zouré. Frontiers in Bioscience (Landmark Edition) 28 (10): 245.

Surgery

Beyond the Gut: Spectrum of Magnetic Surgery Devices. Lee, William G., Lauren L. Evans, and Michael R. Harrison. Frontiers in Surgery 10: 1253728.

Efficacy and Safety of Teprotumumab in Thyroid Eye Disease Patients With Long Duration and Low Disease Activity. Douglas, Raymond S., Steven Couch, Sara T. Wester, Brian T. Fowler, Catherine Y. Liu, Prem S. Subramanian, Rosa Tang, Quang T. Nguyen, Robi N. Maamari, Shoaib Ugradar, Kate Hsu, Michael Karon, and Marius N. Stan. The Journal of Clinical Endocrinology and Metabolism, October, dgad637.

Development and Validation of a Risk Prediction Tool for In-Hospital Mortality After Thoracic Endovascular Repair in Patients With Blunt Thoracic Aortic Injury Using the Aortic Trauma Foundation Registry. D’Oria, Mario, Marco D. Pipitone, Joseph DuBose, Ali Azizzadeh, Charles C. Miller, Benjamin W. Starnes, Valerio S. Tolva, Cassra N. Arbabi, Ilenia D’Alessio, and Sandro Lepidi. Annals of Vascular Surgery, November, S0890-5096(23)00734-3.

Global Cancer Surgery: Pragmatic Solutions to Improve Cancer Surgery Outcomes Worldwide. Are, Chandrakanth, Shilpa S. Murthy, Richard Sullivan, Makayla Schissel, Sanjib Chowdhury, Olesegun Alatise, Daniel Anaya, Madhuri Are, Charles Balch, David Bartlett, Murray Brennan, Lydia Cairncross, Benjamin O. Anderson, et al. The Lancet. Oncology, November, S1470-2045(23)00412-6.

Extremity Vascular Injury: A Western Trauma Association Critical Decisions Algorithm. Fox, Charles J., David V. Feliciano, Jennifer L. Hartwell, Eric J. Ley, Raul Coimbra, Morgan Schellenberg, Marc de Moya, Laura J. Moore, Carlos V. R. Brown, Kenji Inaba, Natasha Keric, Kimberly A. Peck, Nelson G. Rosen, Jordan A. Weinberg, and Matthew J. Martin. The Journal of Trauma and Acute Care Surgery, November.

Endotype Evaluation of Hispanic/Latinx-American Patients With Chronic Rhinosinusitis With Nasal Polyps. Wu, Arthur W., Dennis M. Tang, Kevin Hur, Aria Jafari, Philip G. Chen, Masayoshi Takashima, Elena E. Chang, Bonnie Balzer, Anna Mathew, Mukul Divatia, Haodong Xu, Juliana Robledo, Luv Amin, Benjamin Tam, David J. Cvancara, Amisheila G. Kinua, Tariq A. Syed, Dominique L. Paderin, Missael Vasquez, and Omar G. Ahmed. International Forum of Allergy & Rhinology, November.

Endoscopic Endonasal Surgery for Prolactinomas: Prognostic Factors for Disease Control and Management of Persistent Disease. Kalyvas, Aristotelis, Joao Paulo Almeida, Farshad Nassiri, Ruth Lau, Philip J. O’Halloran, Nilesh Mohan, Thomas Wälchli, Vincent C. Ye, Dennis M. Tang, Pranay Soni, Tamia Potter, Shereen Ezzat, Varun R. Kshettry, Gelareh Zadeh, Pablo F. Recinos, and Fred Gentili. Neurosurgical Review 46 (1): 295.

Incidence Rate and Histology of Appendiceal Neoplasms in Complicated Versus Uncomplicated Appendicitis: A Meta-Analysis and Systematic Review. Solis-Pazmino, Paola, Kimberly Oka, Kristina La, Orly Termeie, Luis A. Figueroa, Eduardo Pilatuna, Daniel Solis-Pazmino, Mary Pat Harnegie, Jason Cohen, Moshe Barnajian, and Yosef Nasseri. Langenbeck’s Archives of Surgery 408 (1): 432.

Comprehensive Treatment Approaches to Obesity. Velazquez, Amanda, and Lee M. Kaplan. Gastroenterology Clinics of North America 52 (4): xi–xii.

Urology

Response to Letter to the Editor Re Residency Graduates Should Not Be Expected to Perform Hypospadias Repair Without Fellowship Training: Results From a Survey of SPU Membership. Masterson, John M., and Andrew L. Freedman. Journal of Pediatric Urology, October, S1477-5131(23)00450-3.

A Proposal for the Comprehensive Care of Men on Androgen Deprivation Therapy: Recommendations From the Multidisciplinary Prostate Cancer 360 Working Group. Crawford, E. David, Marc B. Garnick, Robert H. Eckel, Martin M. Miner, Stephen J. Freedland, Russell K. Pachynski, Richard J. Wassersug, Matthew T. Rosenberg, Lauren M. Walker, Ciaran Fairman, Tracy Curley, Michael Crosby, Pao-Hwa Lin, and Jason M. Hafron. Urology Practice, November, 101097UPJ0000000000000473.