This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Nov. 10-Nov. 17.

Anesthesiology

Design and Implementation of Airway Response Teams to Improve the Practice of Emergency Airway Management. Tankard, Kelly A., Milad Sharifpour, Marvin G. Chang, and Edward A. Bittner. Journal of Clinical Medicine 11 (21): 6336.

Cancer

Differences in the Gut Microbiome by Physical Activity and BMI Among Colorectal Cancer Patients. Himbert, Caroline, W. Zac Stephens, Biljana Gigic, Sheetal Hardikar, Andreana N. Holowatyj, Tengda Lin, Jennifer Ose, Eric Swanson, Anjelica Ashworth, Christy A. Warby, Anita R. Peoples, David Nix, Jolanta Jedrzkiewicz, Mary Bronner, Bartley Pickron, Courtney Scaife, Jessica N. Cohan, Petra Schrotz-King, Nina Habermann, Juergen Boehm, Meredith Hullar, Jane C. Figueiredo, Adetunji T. Toriola, Erin M. Siegel, Christopher I. Li, Alexis B. Ulrich, David Shibata, Kenneth Boucher, Lyen C. Huang, Martin Schneider, June L. Round, and Cornelia M. Ulrich. American Journal of Cancer Research 12 (10): 4789–4801.

Surgical Results of the Lung Cancer Mutation Consortium 3 Trial: A Phase II Multicenter Single-Arm Study to Investigate the Efficacy and Safety of Atezolizumab as Neoadjuvant Therapy in Patients With Stages IB-Select IIIB Resectable Non-Small Cell Lung Cancer. Rusch, Valerie W., Alan Nicholas, G. Alexander Patterson, Salama N. Waqar, Eric M. Toloza, Eric B. Haura, Dan J. Raz, Karen L. Reckamp, Robert E. Merritt, Dwight H. Owen, David J. Finley, Ciaran J. McNamee, Justin D. Blasberg, Edward B. Garon, John D. Mitchell, Robert C. Doebele, Frank Baciewicz, Misako Nagasaka, Harvey I. Pass, Katja Schulze, Ann Johnson, Paul A. Bunn, Bruce E. Johnson, Mark G. Kris, David J. Kwiatkowski, Ignacio I. Wistuba, Jamie E. Chaft, David P. Carbone, and Jay M. Lee. The Journal of Thoracic and Cardiovascular Surgery, October, S0022-5223(22)01055-8.

MiR766-3p and MiR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC. Shibata, Tomohiro, Duo-Yao Cao, Tahir B. Dar, Faizan Ahmed, Shabir A. Bhat, Luciana C. Veiras, Ellen A. Bernstein, Abdul Arif Khan, Manita Chaum, Stephen L. Shiao, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Xiaojiang Cui, Eric Vail, and Zakir Khan. Cancers 14 (21): 5273.

Profiling the Immune Landscape in Mucinous Ovarian Carcinoma. Meagher, Nicola S., Phineas Hamilton, Katy Milne, Shelby Thornton, Bronwyn Harris, Ashley Weir, Jennifer Alsop, Christiani Bisinoto, James D. Brenton, Angela Brooks-Wilson, Derek S. Chiu, Kara L. Cushing-Haugen, Sian Fereday, Dale W. Garsed, Simon A. Gayther, Aleksandra Gentry-Maharaj, Blake Gilks, Mercedes Jimenez-Linan, Catherine J. Kennedy, Nhu D. Le, Anna M. Piskorz, Marjorie J. Riggan, Mitul Shah, Naveena Singh, Aline Talhouk, Martin Widschwendter, David D. L. Bowtell, Francisco J. Candido Dos Reis, Linda S. Cook, Renée T. Fortner, María J. García, Holly R. Harris, David G. Huntsman, Anthony N. Karnezis, Martin Köbel, Usha Menon, Paul D. P. Pharoah, Jennifer A. Doherty, Michael S. Anglesio, Malcolm C. Pike, Celeste Leigh Pearce, Michael L. Friedlander, Anna DeFazio, Brad H. Nelson, and Susan J. Ramus. Gynecologic Oncology 168 (November): 23–31.

Palliative Rehabilitation in Acute Inpatient Rehabilitation: Prognostic Factors and Functional Outcomes in Patients With Cancer. Tennison, Jegy M., Arash Asher, David Hui, Milind Javle, Roland L. Bassett, and Eduardo Bruera. The Oncologist, November, oyac229.

Cardiac Surgery

Symmetric Bicuspidizing Repair for Patients With Congenital Aortic or Truncal Valve Disease. Chiu, Peter, Mariana Chávez, M. Mujeeb Zubair, Kevin G. Friedman, Gerald R. Marx, Pedro J. Del Nido, and Christopher W. Baird. The Journal of Thoracic and Cardiovascular Surgery, October, S0022-5223(22)01131-X.

Sensitization in Congenial Heart Transplantation: Moving the Needle. Emerson, Dominic, and Richard W. Kim. The Annals of Thoracic Surgery, November, S0003-4975(22)01425-4.

Cardiology

Gender and Racial/Ethnic Disparities in Award Distribution by Major Cardiovascular Societies From 2000 to 2021. Iqbal, Kinza, Ashish Kumar, Sawai Singh Rathore, Eisha Farid, Ali Ishaque, Hadiya Afzal, Maha Zahid, Purvi Parwani, Erin D. Michos, and Martha Gulati. Journal of the American College of Cardiology 80 (21): 2050–53.

Dapsone-Associated Anemia in Heart Transplant Recipients With Normal Glucose-6-Phosphate Dehydrogenase Activity. Lor, Kevin W., Evan P. Kransdorf, Jignesh K. Patel, David H. Chang, Jon A. Kobashigawa, and Michelle M. Kittleson. Journal of Clinical Medicine 11 (21): 6378.

Donor Heart Selection: Evidence-Based Guidelines for Providers. Copeland, Hannah, Ivan Knezevic, David A. Baran, Vivek Rao, Michael Pham, Finn Gustafsson, Sean Pinney, Brian Lima, Marco Masetti, Agnieszka Ciarka, Navin Rajagopalan, Adriana Torres, Eileen Hsich, Jignesh K. Patel, Livia Adams Goldraich, Monica Colvin, Javier Segovia, Heather Ross, Mahazarin Ginwalla, Babak Sharif-Kashani, MaryJane A. Farr, Luciano Potena, Jon Kobashigawa, Maria G. Crespo-Leiro, Natasha Altman, Florian Wagner, Jennifer Cook, Valentina Stosor, Paolo A. Grossi, Kiran Khush, Tahir Yagdi, Susan Restaino, Steven Tsui, Daniel Absi, George Sokos, Andreas Zuckermann, Brian Wayda, Joost Felius, and Shelley A. Hall. The Journal of Heart and Lung Transplantation, September, S1053-2498(22)02113-1.

Use of Levosimendan in Patients With Advanced Heart Failure: An Update. Masarone, Daniele, Michelle M. Kittleson, Piero Pollesello, Marco Marini, Massimo Iacoviello, Fabrizio Oliva, Angelo Caiazzo, Andrea Petraio, and Giuseppe Pacileo. Journal of Clinical Medicine 11 (21): 6408.

Social Determinants of Health and Heart Failure: Clinical Takeaways From 5 Pivotal Analyses of the GWTG-HF Registry. Kittleson, Michelle M. Circulation. Heart Failure 15 (11): e010022.

Change in First-Year Intravascular Ultrasound Results Predicts Adverse Events in Heart Transplant Recipients: Implications for Clinical Trial Endpoints. Seguchi, Osamu, Babak Azarbal, James Mirocha, Jong-Chan Youn, Elizabeth Passano, Jignesh Patel, and Jon Kobashigawa. Transplantation, November.

Heart and Brain Interactions: Is Small Vessel Disease a Link? Pepine, Carl J., and C. Noel Bairey Merz. European Heart Journal, November, ehac570.

How to Minimize In-Hospital Mortality From Acute Myocardial Infarction: Focus on Primary Prevention of Ventricular Fibrillation. Holmstrom, Lauri, and Sumeet S. Chugh. European Heart Journal, November, ehac578.

Knowledge of Genome Sequencing and Trust in Medical Researchers Among Patients of Different Racial and Ethnic Groups With Idiopathic Dilated Cardiomyopathy. Ni, Hanyu, Elizabeth Jordan, Jinwen Cao, Daniel D. Kinnamon, Stephen S. Gottlieb, Mark Hofmeyer, Javier Jimenez, Daniel P. Judge, Evan Kransdorf, Alanna A. Morris, Anjali Owens, Palak Shah, W. H. Wilson Tang, Jessica Wang, and Ray E. Hershberger. JAMA Cardiology, November.

Recurrent Out-of-Hospital Sudden Cardiac Arrest: Prevalence and Clinical Factors. Held, Elizabeth P., Kyndaron Reinier, Harpriya Chugh, Audrey Uy-Evanado, Jonathan Jui, and Sumeet S. Chugh. Circulation: Arrhythmia and Electrophysiology 0 (0): e011018. Accessed November 17.

Imaging

Plaque Burden and 1-Year Outcomes in Acute Chest Pain: Results From the Multicenter RAPID-CTCA Trial. Meah, Mohammed N., Evangelos Tzolos, Kang-Ling Wang, Anda Bularga, Marc R. Dweck, Nick Curzen, Attila Kardos, Liza Keating, Robert F. Storey, Nicholas L. Mills, Piotr J. Slomka, Damini Dey, David E. Newby, Alasdair Gray, Michelle C. Williams, and Carl Roobottom. JACC. Cardiovascular Imaging 15 (11): 1916–25.

Mortality Impact of Low CAC Density Predominantly Occurs in Early Atherosclerosis: Explainable ML in the CAC Consortium. Lin, Fay Y., Benjamin P. Goebel, Benjamin C. Lee, Yao Lu, Lohendran Baskaran, Yeonyee E. Yoon, Gabriel Thomas Maliakal, Umberto Gianni, A. Maxim Bax, Partho P. Sengupta, Piotr J. Slomka, Damini S. Dey, Alan Rozanski, Donghee Han, Daniel S. Berman, Matthew J. Budoff, Michael D. Miedema, Khurram Nasir, John Rumberger, Seamus P. Whelton, Michael J. Blaha, and Leslee J. Shaw. Journal of Cardiovascular Computed Tomography, November, S1934-5925(22)00288-X.

Glycemic Control Is Independently Associated With Rapid Progression of Coronary Atherosclerosis in the Absence of a Baseline Coronary Plaque Burden: A Retrospective Case-Control Study From the PARADIGM Registry. Won, Ki-Bum, Byoung Kwon Lee, Fay Y. Lin, Martin Hadamitzky, Yong-Jin Kim, Ji Min Sung, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J. Budoff, Ilan Gottlieb, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Pedro de Araújo Gonçalves, Jonathon A. Leipsic, Sang-Eun Lee, Sanghoon Shin, Jung Hyun Choi, Renu Virmani, Habib Samady, Kavitha Chinnaiyan, Daniel S. Berman, Jagat Narula, Leslee J. Shaw, Jeroen J. Bax, James K. Min, and Hyuk-Jae Chang. Cardiovascular Diabetology21 (1): 239.

Medicine

Both Donor Specific and Non-Donor Specific HLA Antibodies Reduced in Recipients Post Simultaneous Liver/Kidney Transplant. Zhang, Xiaohai, Steven A. Wisel, Mark Haas, Irene Kim, and Stanley Jordan. Transplant Immunology 75 (November): 101744.

Complementary Feeding and Child Appetitive Traits in a Sample of Hispanic Mother-Child Dyads. Schneider-Worthington, Camille R., Marie Lauzon, Paige K. Berger, Michael I. Goran, and Sarah-Jeanne Salvy. Journal of the Academy of Nutrition and Dietetics, November, S2212-2672(22)01156-X.

The Initiation of Oxidative Stress and Therapeutic Strategies in Wound Healing. Wang, Gang, Feifei Yang, Weiying Zhou, Nanyang Xiao, Mao Luo, and Zonghao Tang. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 157 (November): 114004.

Crohn’s Disease Shared Decision Making Intervention Leads to More Patients Choosing Combination Therapy: A Cluster Randomised Controlled Trial. Zisman-Ilani, Yaara, Kimberly D. Thompson, Lori S. Siegel, Todd Mackenzie, Damara J. Crate, Joshua R. Korzenik, Gil Y. Melmed, Patricia Kozuch, Bruce E. Sands, David T. Rubin, Miguel D. Regueiro, Raymond Cross, Douglas C. Wolf, John S. Hanson, Ronald M. Schwartz, Raluca Vrabie, Michael D. Kreines, Timothy Scherer, Marla C. Dubinsky, and Corey A. Siegel. Alimentary Pharmacology & Therapeutics, November.

Development of a Clinical Prediction Model for Diabetes in Chronic Pancreatitis: The PREDICT3c Study. Jeon, Christie, Phil A. Hart, Liang Li, Yunlong Yang, Eleanor Chang, Melena D. Bellin, William E. Fisher, Evan L. Fogel, Christopher E. Forsmark, Walter G. Park, Stephen K. Van Den Eeden, Santhi Swaroop Vege, Jose Serrano, David C. Whitcomb, Dana K. Andersen, Darwin L. Conwell, Dhiraj Yadav, Mark O. Goodarzi, and Diabetes on behalf of the Consortium for the Study of Chronic Pancreatitis and Pancreatic Cancer (CPDPC). Diabetes Care, November, dc221414.

Evaluating the Impact of Assessment Metrics for Simulated Central Venous Catheterization Training. Brown, Dailen C., Jessica M. Gonzalez-Vargas, Haroula M. Tzamaras, Elizabeth H. Sinz, Philip K. Ng, Michael X. Yang, Sanjib D. Adhikary, Scarlett R. Miller, and Jason Z. Moore. Simulation in Healthcare: Journal of the Society for Simulation in Healthcare, November.

A Class Effect Network Meta-Analysis of Lipid Modulation in Non-Alcoholic Steatohepatitis for Dyslipidemia. Xiao, Jieling, Cheng-Han Ng, Yip-Han Chin, Darren Jun Hao Tan, Wen-Hui Lim, Grace Lim, Jingxuan Quek, Ansel Shao Pin Tang, Kai-En Chan, Rou-Yi Soong, Nicholas Chew, Benjamin Tay, Daniel Q. Huang, Nobuharu Tamaki, Roger Foo, Mark Y. Chan, Mazen Noureddin, Mohammad Shadab Siddiqui, Arun J. Sanyal, and Mark D. Muthiah. Journal of Clinical and Translational Hepatology 10 (6): 1042–49.

Neurology

Tips in Navigating the Diagnostic Complexities of Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Lewis, Richard A., Pieter A. van Doorn, and Claudia Sommer. Journal of the Neurological Sciences 443 (October): 120478.

17?-Estradiol Ameliorates Delirium-like Phenotypes in a Murine Model of Urinary Tract Infection. Guidry, Gena, Nicklaus A. Sparrow, Hyyat S. Marshall, Roberta De Souza Santos, Suman P. Bharath, Michael M. Gezalian, Margareta D. Pisarska, Jean-Philippe Vit, Scott A. Kelly, S. Ananth Karumanchi, and Shouri Lahiri. Scientific Reports 12 (1): 19622.

Distinct Signatures of Loss of Consciousness in Focal Impaired Awareness Versus Tonic-Clonic Seizures. Juan, Elsa, Urszula Górska, Csaba Kozma, Cynthia Papantonatos, Tom Bugnon, Colin Denis, Vaclav Kremen, Greg Worrell, Aaron F Struck, Lisa M Bateman, Edward M Merricks, Hal Blumenfeld, Giulio Tononi, Catherine Schevon, and Melanie Boly. Brain, November, awac291.

OBGYN

Infertility and Treatments Utilized Have Minimal Effects on First Trimester Placenta DNA Methylation and Gene Expression. Gonzalez, Tania L., Amelia M. Schaub, Bora Lee, Jinrui Cui, Kent D. Taylor, Anna E. Dorfman, Mark O. Goodarzi, Erica T. Wang, Yii-Der Ida Chen, Jerome I. Rotter, Rimsha Hussaini, Paige M. Harakuni, Mayaal H. Khan, Stephen S. Rich, Charles R. Farber, John Williams, and Margareta D. Pisarska. Fertility and Sterility, November, S0015-0282(22)02037-4.

Gestational Carrier Use and Twin Pregnancy: A Start Review of Trends in Assisted Reproductive Technology. Wong, AJ, B. E. Willson, and Murray Mj. Fertility and Sterility 118 (5, Supplement): e13–14.

Method of Hysteroscopic Procedure for Polyps Impacts Myometrium Identification in Pathology Specimens. Schaub, A, Bui C, Wang Et, Wright K, Hussaini R, Novoa A, Medeiros F, and Pisarska Md. Fertility and Sterility 118 (5, Supplement): e16.

Pathology

Trypanosoma Brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase With Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity. Brown, Robert W. B., Aabha I. Sharma, Miguel Rey Villanueva, Xiaomo Li, Ouma Onguka, Leeor Zilbermintz, Helen Nguyen, Ben A. Falk, Cheryl L. Olson, Joann M. Taylor, Conrad L. Epting, Rahul S. Kathayat, Neri Amara, Bryan C. Dickinson, Matthew Bogyo, and David M. Engman. Pathogens (Basel, Switzerland) 11 (11): 1245.

The Pro-B-Type Natriuretic Peptide Dilemma in Hematopoietic Progenitor Cell Collection. Baykara, Yigit, Samuel H. Pepkowitz, and Yamac Akgun. Journal of Clinical Apheresis, November.

Influence of Sodium Bicarbonate on Wall Teichoic Acid Synthesis and ?-Lactam Sensitization in NaHCO3-Responsive and Nonresponsive Methicillin-Resistant Staphylococcus Aureus. Ersoy, Selvi C., Barbara Gonçalves, Gonçalo Cavaco, Adhar C. Manna, Rita G. Sobral, Cynthia C. Nast, Richard A. Proctor, Henry F. Chambers, Ambrose Cheung, and Arnold S. Bayer. Microbiology Spectrum, November, e0342222.

Pediatrics

Editorial Overview: How to Generate and Maintain Organs-Organoids, Regeneration, and Beyond. Klein, Ophir D., and Ryuichi Nishinakamura. Current Opinion in Genetics & Development 77 (October): 102003.

Impact of Udenafil on Echocardiographic Indices of Single Ventricle Size and Function in FUEL Study Participants. Di Maria, Michael V., David J. Goldberg, Victor Zak, Chenwei Hu, Adam M. Lubert, Andreea Dragulescu, Andrew S. Mackie, Andrew McCrary, Angela Weingarten, Anitha Parthiban, Benjamin Goot, Bryan H. Goldstein, Carolyn Taylor, Christopher Lindblade, Christopher J. Petit, Christopher Spurney, David M. Harrild, Elaine M. Urbina, Eleanor Schuchardt, Gi Beom Kim, Ja Kyoung Yoon, Jamie N. Colombo, Matthew D. Files, Megan Schoessling, Peter Ermis, Pierre C. Wong, Ruchira Garg, Sara K. Swanson, Shaji C. Menon, Shubhika Srivastava, Thor Thorsson, Tiffanie R. Johnson, Usha S. Krishnan, Stephen M. Paridon, Peter C. Frommelt, and Pediatric Heart Network. Circulation. Cardiovascular Imaging 15 (11): e013676.

Surgery

Campaign Reform for US News and World Report Rankings. Daskivich, TJ, and BL Gewertz. JAMA Surgery, November.