This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Jan. 18-25. 

Anesthesiology

Quality Metrics for Cesarean Delivery: More Than Just General Anesthesia Rates. Hofkamp, Michael P., Emily E. Sharpe, Mark I. Zakowski, and Robert S. White. Journal of Clinical Anesthesia 94 (January): 111398.

Biomedical Sciences 

Rapid Three-Dimensional Quantification of High-Intensity Plaques From Coronary Atherosclerosis T1-Weighted Characterization to Predict Periprocedural Myocardial Injury. Nakazawa, Motoki, Hidenari Matsumoto, Debiao Li, Piotr J. Slomka, Dey Damini, Sebastien Cadet, Koji Isodono, Daisuke Irie, Satoshi Higuchi, Hiroki Tanisawa, Hidefumi Ohya, Ryoji Kitamura, Yoshiaki Komori, Tetsuichi Hondera, Ikumi Sato, Hsu-Lei Lee, Anthony G. Christodoulou, Yibin Xie, and Toshiro Shinke. Journal of Cardiovascular Magnetic Resonance, January, 100999.

The Future of CMR: All-in-One vs. Real-Time CMR (Part 1). Christodoulou, Anthony G., Gastao Cruz, Ayda Arami, Sebastian Weingärtner, Jessica Artico, Dana Peters, and Nicole Seiberlich. Journal of Cardiovascular Magnetic, January, 100997.

Use of Coronarycomputed Tomography for Cardiovascular Risk Assessment in Immune-Mediated Inflammatory Diseases. Peverelli, Marta, Robert T. Maughan, Deepa Gopalan, Marc R. Dweck, Damini Dey, Maya H. Buch, James H. F. Rudd, and Jason M. Tarkin. Heart (British Cardiac Society), January, heartjnl-2022-321403.

Multi-Lineage Heart-Chip Models Drug Cardiotoxicity and Enhances Maturation of Human Stem Cell-Derived Cardiovascular Cells. Mozneb, Maedeh, Amelia Jenkins, Samuel Sances, Stephany Pohlman, Michael J. Workman, Dylan West, Briana Ondatje, Kareem El-Ghazawi, Amanda Woodbury, Veronica J. Garcia, Shachi Patel, Madelyn Arzt, Felipe Dezem, Alex H. Laperle, V. Alexandra Moser, Ritchie Ho, Nur Yucer, Jasmine Plummer, Robert J. Barrett, Clive N. Svendsen, and Arun Sharma. Lab on a Chip, January.

Cardiac Surgery

Surgery and Transcatheter Intervention for Degenerative Mitral Regurgitation in the United States. Chikwe, Joanna, Qiudong Chen, Michael E. Bowdish, Amy Roach, Dominic Emerson, Annetine Gelijns, and Natalia Egorova. The Journal of Thoracic and Cardiovascular Surgery, January, S0022-5223(24)00027-8.

Cardiology 

JCL Roundtable: Evolution of Preventive Cardiology and Clinical Lipidology. Gulati, Martha, Erin D. Michos, William E. Boden, and John R. Guyton. Journal of Clinical Lipidology, December, S1933-2874(23)00354-9.

Prevalence and Treatment of Atrial Fibrillation and Flutter in Cardiac Amyloidosis. Haslett, Jack J., Nikhil Patel, Michelle M. Kittleson, and Jignesh K. Patel. JACC. Clinical Electrophysiology, January, S2405-500X(23)00895-2.

Racial and Ethnic Disparities in Co-Occurrence of Nocturnal Hypertension and Nocturnal Blood Pressure Decreases. Zhang, Neil, Tzu Yu Huang, Susan Cheng, and Joseph E. Ebinger. JAMA Network Open 7 (1): e2352227.

Modern Advances in Heart Transplantation. Srivastava, Pratyaksh K., and Michelle M. Kittleson. Progress in Cardiovascular Diseases, January, S0033-0620(24)00012-4.

Reply to Pendyal, A.-Long-Term Adverse Outcomes in Black Women With Obstructive Coronary Artery Disease: A Study of the Women’s Ischemia Syndrome Evaluation (WISE) Cohort. Luu, Judy M., C. Noel Bairey Merz, and Janet Wei. The Canadian Journal of Cardiology, January, S0828-282X(24)00022-9.

Blood Pressure Variability Supersedes Heart Rate Variability as a Real-World Measure of Dementia Risk. Ebinger, Joseph E., Matthew P. Driver, Tzu Yu Huang, Jose Magraner, Patrick G. Botting, Minhao Wang, Peng-Sheng Chen, Natalie A. Bello, David Ouyang, John Theurer, Susan Cheng, and Zaldy S. Tan. Scientific Reports 14 (1): 1838.

Study the Relationship Between Left Atrial (LA) Volume and LV Diastolic Dysfunction and LV Hypertrophy: Correlate LA Volume With Cardiovascular Risk Factors. Pawar, Shubhadarshini G., Praveen Bharath Saravanan, Shipra Gulati, Shefali Pati, Muskan Joshi, Ajal Salam, and Nida Khan. Disease-a-Month: DM, January, 101675.

Moving Towards Establishing Centres of Excellence in Cardiac Amyloidosis: An International Cardio-Oncology Society Statement. Cheng, Richard, Michelle M. Kittleson, Ashutosh D. Wechalekar, Jose Alvarez-Cardona, Joshua D. Mitchell, Ariane Vieira Scarlatelli Macedo, Joao Pedro Passos Dutra, Courtney M. Campbell, Jennifer E. Liu, Heather J. Landau, Margot K. Davis, Siobhain Morrissey, Stephen Casselli, Isabelle Lousada, Juliane Dantas Seabra-Garcez, Roberta Shcolnik Szor, Sarju Ganatra, Barry Trachtenberg, Mathew S. Maurer, Keith Stockerl-Goldstein, and Daniel Lenihan. Heart (British Cardiac Society), January, heartjnl-2023-323502.

Drawing Conclusions From Exploratory Analyses: A Slippery Slope. Kaul, Sanjay, G. B. John Mancini, William S. Weintraub, Raffaele De Caterina, and INTEGRITTY. Journal of the American College of Cardiology 83 (4): e31.

Racial and Ethnic Disparities in Perioperative Health Care Among Patients Undergoing Cardiac Surgery: JACC State-of-the-Art Review. Milam, Adam J., Modele O. Ogunniyi, Abimbola O. Faloye, Luis R. Castellanos, Ricardo E. Verdiner, James W. Stewart, Merije Chukumerije, Alexis K. Okoh, Steven Bradley, Robert O. Roswell, Paul L. Douglass, Shakirat O. Oyetunji, Alexander Iribarne, Debra Furr-Holden, Harish Ramakrishna, and Sharonne N. Hayes. Journal of the American College of Cardiology 83 (4): 530–45.

Computational Biomedicine

Biomarkers in Alzheimer’s Disease: Are Olfactory Neuronal Precursors Useful for Antemortem Biomarker Research? Santillán-Morales, Valeria, Norberto Rodriguez-Espinosa, Jesús Muñoz-Estrada, Salvador Alarcón-Elizalde, Ángel Acebes, and Gloria Benítez-King. Brain Sciences 14 (1): 46.

GRAIL-Galleri: Why the Special Treatment? Turnbull, Clare, Nicholas Wald, Richard Sullivan, Paul Pharoah, Richard S. Houlston, Ajay Aggarwal, Stuart Hogarth, and Margaret McCartney. Lancet (London, England), January, S0140-6736(23)02830-1.

Relation Detection to Identify Stroke Assertions From Clinical Notes Using Natural Language Processing. Yang, Audrey, Sam Kamien, Anahita Davoudi, Sy Hwang, Meet Gandhi, Ryan Urbanowicz, and Danielle Mowery. Studies in Health Technology and Informatics 310 (January): 619–23.

Imaging

Is Typical Angina Still Prognostically Important? The Influence of ‘Treatment Bias’ Upon Prognostic Assessments. Rozanski, Alan, Donghee Han, Robert J. H. Miller, Heidi Gransar, Sean W. Hayes, John D. Friedman, Louise Thomson, and Daniel S. Berman. Journal of Nuclear Cardiology, 101778.

Comparative Predictors of Mortality Among Patients Referred for Stress SPECT Versus PET Myocardial Perfusion Imaging. Rozanski, Alan, Robert J. H. Miller, Donghee Han, Heidi Gransar, Sean W. Hayes, John D. Friedman, Louise E. J. Thomson, and Daniel S. Berman. Journal of Nuclear Cardiology, January, 101811.

Imaging of Lower Extremity Infections: Predisposing Conditions, Atypical Infections, Mimics, and Differentiating Features. Matcuk, George R., Sanaz Katal, Ali Gholamrezanezhad, Paolo Spinnato, Leah E. Waldman, Brandon K. K. Fields, Dakshesh B. Patel, and Matthew R. Skalski. Skeletal Radiology, January.

Lower Extremity Infections: Essential Anatomy and Multimodality Imaging Findings. Matcuk, George R., Matthew R. Skalski, Dakshesh B. Patel, Brandon K. K. Fields, Leah E. Waldman, Paolo Spinnato, Ali Gholamrezanezhad, and Sanaz Katal. Skeletal Radiology, January.

Medicine

The Global Burden of Early-Onset Biliary Tract Cancer: Insight From the Global Burden of Disease Study 2019. Danpanichkul, Pojsakorn, Cheng H. Ng, Darren J. H. Tan, Mark D. Muthiah, Siwanart Kongarin, Karan Srisurapanont, Yatawee Kanjanakot, Kwanjit Duangsonk, Daniel Q. Huang, Hiroyuki Suzuki, Denise M. Harnois, Ju D. Yang, Mazen Noureddin, and Karn Wijarnpreecha. Journal of Clinical and Experimental Hepatology 14 (2): 101320.

Associations of Galectin-3 Levels With Measures of Vascular Disease in Patients With Rheumatoid Arthritis. Nussdorf, Amanda, Elizabeth Park, Isabelle Amigues, Laura Geraldino-Pardilla, Sabahat Bokhari, Jon T. Giles, and Joan M. Bathon. Seminars in Arthritis and Rheumatism 65 (January): 152357.

Individualised Neoantigen Therapy mRNA-4157 (V940) Plus Pembrolizumab Versus Pembrolizumab Monotherapy in Resected Melanoma (KEYNOTE-942): A Randomised, Phase 2b Study. Weber, Jeffrey S., Matteo S. Carlino, Adnan Khattak, Tarek Meniawy, George Ansstas, Matthew H. Taylor, Kevin B. Kim, Meredith McKean, Georgina V. Long, Ryan J. Sullivan, Mark Faries, Thuy T. Tran, C. Lance Cowey, Andrew Pecora, Montaser Shaheen, Jennifer Segar, Theresa Medina, Victoria Atkinson, Geoffrey T. Gibney, Jason J. Luke, Sajeve Thomas, Elizabeth I. Buchbinder, Jane A. Healy, Mo Huang, Manju Morrissey, Igor Feldman, Vasudha Sehgal, Celine Robert-Tissot, Peijie Hou, Lili Zhu, Michelle Brown, Praveen Aanur, Robert S. Meehan, and Tal Zaks. Lancet (London, England), January, S0140-6736(23)02268-7.

SKA3 Targeted Therapies in Cancer Precision Surgery: Bridging Bench Discoveries to Clinical Applications-Review Article. Feng, Dechao, Jie Wang, Yuhan Xiao, Ruicheng Wu, Dengxiong Li, Zhouting Tuo, Qingxin Yu, Luxia Ye, Akira Miyamoto, Koo Han Yoo, Wuran Wei, Xing Ye, Chi Zhang, and Ping Han. International Journal of Surgery (London, England), January.

Achievement of Clinical, Endoscopic, and Histologic Outcomes in Patients With Ulcerative Colitis Treated With Etrasimod, and Association With Fecal Calprotectin and C-Reactive Protein: Results From the Phase 2 OASIS Trial. Yarur, Andres J., Michael V. Chiorean, Julián Panés, Vipul Jairath, Jinkun Zhang, Christopher J. Rabbat, William J. Sandborn, Séverine Vermeire, and Laurent Peyrin-Biroulet. Journal of Crohn’s & Colitis, January, jjae007.

Centering Equity in Cardiovascular Health Technology Assessment. Vervoort, Dominique, Aminah Sallam, Stephen E. Fremes, Harindra C. Wijeysundera, and Derrick Y. Tam.

Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature. Thomas, Claire E., Peter Georgeson, Conghui Qu, Robert S. Steinfelder, Daniel D. Buchanan, Mingyang Song, Tabitha A. Harrison, Caroline Y. Um, Meredith A. Hullar, Mark A. Jenkins, Bethany Van Guelpen, Brigid M. Lynch, Yohannes Adama Melaku, Jeroen R. Huyghe, Elom K. Aglago, Sonja I. Berndt, Lisa A. Boardman, Peter T. Campbell, Yin Cao, Andrew T. Chan, David A. Drew, Jane C. Figueiredo, Amy J. French, Marios Giannakis, Ellen L. Goode, Stephen B. Gruber, Andrea Gsur, Marc J. Gunter, Michael Hoffmeister, Li Hsu, Wen-Yi Huang, Victor Moreno, Neil Murphy, Polly A. Newcomb, Christina C. Newton, Jonathan A. Nowak, Mireia Obón-Santacana, Shuji Ogino, Wei Sun, Amanda E. Toland, Quang M. Trinh, Tomotaka Ugai, Syed H. Zaidi, Ulrike Peters, and Amanda I. Phipps. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, January.

Reply to ‘The Shift of Therapeutic Strategy for Prolactinomas: Surgery as the First-Line Option.’ Petersenn, Stephan, Maria Fleseriu, and Shlomo Melmed. Nature Reviews. Endocrinology, January.

The Impact of an Increased Fibrosis-4 Index and the Severity of Hepatic Steatosis on Mortality in Individuals Living With Diabetes. Ma, Xiaoyan, Yixuan Zhu, Yee Hui Yeo, Zhiwen Fan, Xiaoming Xu, Fajuan Rui, Wenjing Ni, Qi Gu, Xin Tong, Shengxia Yin, Xiaolong Qi, Junping Shi, Chao Wu, and Jie Li. Hepatology International, January.

Downward Myocardial Creep During Stress PET Imaging Is Inversely Associated With Mortality. Kuronuma, Keiichiro, Robert J. H. Miller, Chih-Chun Wei, Ananya Singh, Mark H. Lemley, Serge D. Van Kriekinge, Paul B. Kavanagh, Heidi Gransar, Donghee Han, Sean W. Hayes, Louise Thomson, Damini Dey, John D. Friedman, Daniel S. Berman, and Piotr J. Slomka. European Journal of Nuclear Medicine and Molecular Imaging, January.

Orofacial Complications From Immune Checkpoint Inhibitors: A Retrospective Analysis From Two Academic Medical Centers. Al-Eryani, Kamal, Joel B. Epstein, Anette Vistoso Monreal, and Alessandro Villa. Head & Neck, January.

Advances in Nanotechnology-Assisted Photodynamic Therapy for Neurological Disorders: A Comprehensive Review. Nasir, Abdul, Mujeeb Ur Rehman, Tamreez Khan, Mansoor Husn, Manzar Khan, Ahmad Khan, Abdifatah Mohamed Nuh, Wei Jiang, Hafiz Muhammad Umer Farooqi, and Qain Bai. Artificial Cells, Nanomedicine, and Biotechnology 52 (1): 84–103.

Neurosurgery

Drug Resistance in Glioblastoma: From Chemo- to Immunotherapy. Sharma, Sachin, Oksana Chepurna, and Tao Sun. Cancer Drug Resistance (Alhambra, Calif.) 6 (4): 688–708.

Dataset of Human-Single Neuron Activity During a Sternberg Working Memory Task. Kyzar, Michael, Jan Kami?ski, Aneta Brzezicka, Chrystal M. Reed, Jeffrey M. Chung, Adam N. Mamelak, and Ueli Rutishauser. Scientific Data 11 (1): 89.

A Prospective Study of Lumbar Facet Arthroplasty in the Treatment of Degenerative Spondylolisthesis and Stenosis: Cost-Effective Assessment From the Total Posterior Spine (TOPSTM) System IDE Study: 2-Year Model Revision and Sensitivity Analyses Based on 305 Subjects. Ament, Jared D., Jack Petros, Tina Zabehi, Randy Yee, J. Patrick Johnson, and Amir Vokshoor. The Spine Journal, January, S1529-9430(24)00011-1.

Future of Endovascular and Surgical Treatments of Atherosclerotic Intracranial Stenosis. Elder, Theresa A., Timothy G. White, Henry H. Woo, Adnan H. Siddiqui, Ravi Nunna, Farhan Siddiq, Giuseppe Esposito, Daniel Chang, Nestor R. Gonzalez, and Sepideh Amin-Hanjani. Stroke 55 (2): 344–54.

OBGYN

Sensitivity of Antenatal Ultrasound in Diagnosing Posterior Placenta Accreta Spectrum Disorders. Dellapiana, Gabriela, Thalia Mok, Lawrence D. Platt, Neil S. Silverman, Christina S. Han, and Tania F. Esakoff. Journal of Perinatal Medicine, January.

Orthopaedics

Evaluating Funding for Authors Achieving High Citations vs. Online Popularity. Farivar, Daniel, Amar S. Vadhera, Kenneth D. Illingworth, and David L. Skaggs. The Journal of the American Academy of Orthopaedic Surgeons, January.

Biomechanical Comparison of FiberLock Suspensionplasty and Flexor Carpi Radialis Ligament Reconstruction for Treatment of Thumb Carpometacarpal Osteoarthritis. Nakla, Andrew P., Steven S. Shin, Daniel Kwak, Min-Shik Chung, Michelle H. McGarry, and Thay Q. Lee. Hand (New York, N.Y.), January, 15589447231222565.

Pathology and Laboratory Medicine

The Future of Digital Cytology and Artificial Intelligence: An Editorial Commentary for Digital Cytology Part 1 and 2. Levy, Joshua, and Keluo Yao. Journal of the American Society of Cytopathology, December, S2213-2945(23)00261-2.

Intraoperative Margin Assessment for Basal Cell Carcinoma With Deep Learning and Histologic Tumor Mapping to Surgical Site. Levy, Joshua J., Matthew J. Davis, Rachael S. Chacko, Michael J. Davis, Lucy J. Fu, Tarushii Goel, Akash Pamal, Irfan Nafi, Abhinav Angirekula, Anish Suvarna, Ram Vempati, Brock C. Christensen, Matthew S. Hayden, Louis J. Vaickus, and Matthew R. LeBoeuf. NPJ Precision Oncology 8 (1): 2.

Determining Susceptibility and Potential Mediators of Resistance for the Novel Polymyxin Derivative, SPR206, in Acinetobacter Baumannii. Abdul-Mutakabbir, Jacinda C., Nana Sakyi Opoku, Karen K. Tan, Peter Jorth, Victor Nizet, Hansel M. Fletcher, Keith S. Kaye, and Michael J. Rybak. Antibiotics (Basel, Switzerland) 13 (1): 47.

Endocrine-Sensitive Disease Rate in Postmenopausal Patients With Estrogen Receptor-Rich/ERBB2-Negative Breast Cancer Receiving Neoadjuvant Anastrozole, Fulvestrant, or Their Combination: A Phase 3 Randomized Clinical Trial. Ma, Cynthia X., Vera J. Suman, Souzan Sanati, Kiran Vij, Meenakshi Anurag, A. Marilyn Leitch, Gary W. Unzeitig, Jeremy Hoog, Aranzazu Fernandez-Martinez, Cheng Fan, Richard A. Gibbs, Mark A. Watson, Travis J. Dockter, Olwen Hahn, Joseph M. Guenther, Abigail Caudle, Erika Crouch, Amy Tiersten, Monica Mita, Wajeeha Razaq, Tina J. Hieken, Yang Wang, Mothaffar F. Rimawi, Anna Weiss, Eric P. Winer, Kelly K. Hunt, Charles M. Perou, Matthew J. Ellis, Ann H. Partridge, and Lisa A. Carey. JAMA Oncology, January, e236038.

Histologic and Clinical Factors Associated With Kidney Outcomes in IgA Vasculitis Nephritis. Barbour, Sean J., Rosanna Coppo, Lee Er, Evangeline Pillebout, Maria Luisa Russo, Charles E. Alpers, Agnes B. Fogo, Franco Ferrario, J. Charles Jennette, Ian S. D. Roberts, H. Terence Cook, Jie Ding, Mark Haas, et al. Clinical Journal of the American Society of Nephrology: CJASN, January.

Improving Frozen Section Evaluation of Procurement Donor Kidney Biopsies and Reducing the Discard Rate: A Promising Role for Artificial Intelligence. Haas, Mark. Kidney International 105 (2): 240–42.

Pediatrics

Enhancing Healthcare Communication Education: Standardised Patient Programmes. Nawathe, Pooja A., and Alaina Herrington. Indian Journal of Anaesthesia 68 (1): 65.

Gatad2b, Associated With the Neurodevelopmental Syndrome GAND, Plays a Critical Role in Neurodevelopment and Cortical Patterning. Abad, Clemer, Maria C. Robayo, Maria Del Mar Muñiz-Moreno, Maria T. Bernardi, Maria G. Otero, Christina Kosanovic, Anthony J. Griswold, Tyler Mark Pierson, Katherina Walz, and Juan I. Young. Translational Psychiatry 14 (1): 33.

Surgery

Optimizing the Postoperative Management of Children Undergoing Resection of High-Risk Abdominal Neuroblastoma. Lee, William G., Danny Lascano, Samiza B. Palmer, Stephanie Y. Chen, Shale J. Mack, Rasika Sudharshan, Jane S. Han, and Eugene S. Kim. The American Surgeon, January. 31348241227199.

Differential Diagnosis of ‘Foot Drop’: Implications for Peripheral Nerve Surgery. Seruya, Mitchel. Journal of Reconstructive Microsurgery, January.

Urology

Potential Miscommunication of Risk in American College of Radiology Prostate Imaging and Data System (PIRADS) Scores. Dallmer, Jeremiah R., Brennan Spiegel, Stephen J. Freedland, Rola Saouaf, Paige Kuhlmann, and Timothy J. Daskivich. Prostate Cancer and Prostatic Diseases, January.

Prevalence of Sexual Dysfunction and Pursuit of Sexual Medicine Evaluation Among Male Physicians-a Survey. Lin, Jasmine S., Justin M. Dubin, Jonathan Aguiar, Daniel R. Greenberg, Nelson E. Bennett, Robert E. Brannigan, and Joshua A. Halpern. International Journal of Impotence Research, January.

The Molecular Twin Artificial-Intelligence Platform Integrates Multi-Omic Data to Predict Outcomes for Pancreatic Adenocarcinoma Patients. Osipov, Arsen, Ognjen Nikolic, Arkadiusz Gertych, Sarah Parker, Andrew Hendifar, Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R. Ferrone, Lei Zheng, Jason H. Moore, Warren Tourtellotte, Jennifer E. Van Eyk, and Dan Theodorescu. Nature Cancer, January.