This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Feb. 29-March 7.

Biomedical Sciences

Online Dating: Predictors of Problematic Tinder Use. Vera Cruz, Germano, Elias Aboujaoude, Lucien Rochat, Francesco Bianchi-Demicheli, and Yasser Khazaal. BMC Psychology 12 (1): 106.

Genome-Wide Association Analyses of Ovarian Cancer Patients Undergoing Primary Debulking Surgery Identify Candidate Genes for Residual Disease. Ramachandran, Dhanya, Jonathan P. Tyrer, Stefan Kommoss, Anna DeFazio, Marjorie J. Riggan, AOCS Group, Penelope M. Webb, Peter A. Fasching, Diether Lambrechts, María J. García, Cristina Rodríguez-Antona, Marc T. Goodman, Florian Heitz, et al. NPJ Genomic Medicine 9 (1): 19.

Prior Exposure to Experimental Preeclampsia Increases Atherosclerotic Plaque Inflammation in Atherogenic Mice. Biwer, Lauren A., Joshua J. Man, Nicholas D. Camarda, Brigett V. Carvajal, S. Ananth Karumanchi, and Iris Z. Jaffe. Arteriosclerosis, Thrombosis, and Vascular Biology, March.

Cardiology

The Sights of Sound: MRI and Histopathological Analysis of a Steam-Pop During Bipolar Ablation. Noori, Arshia M., Shreel Joshi, Debbie L. Teodorescu, Alan C. Kwan, Daniel J. Luthringer, and Ashkan Ehdaie. JACC. Clinical Electrophysiology, January, S2405-500X(24)00017-3.

Machine Learning in Imaging: What Is JASE Looking For? Ouyang, David, Rickey E. Carter, and Patricia A. Pellikka. Journal of the American Society of Echocardiography, 37 (3): 273–75.

A Novel Micropeptide, Slitharin, Exerts Cardioprotective Effects in Myocardial Infarction. Ibrahim, Ahmed G. E., Alessandra Ciullo, Shukuro Yamaguchi, Chang Li, Travis Antes, Xaviar Jones, Liang Li, Ramachandran Murali, Innokentiy Maslennikov, Niveda Sundararaman, Daniel Soetkamp, Eugenio Cingolani, Jennifer Van Eyk, and Eduardo Marbán. Proteomics. Clinical Applications, March, e2300128.

Computational Biomedicine

Cluster Analysis Reveals Socioeconomic Disparities Among Elective Spine Surgery Patients. Orlenko, Alena, Philip J. Freda, Attri Ghosh, Hyunjun Choi, Nicholas Matsumoto, Tiffani J. Bright, Corey T. Walker, Tayo Obafemi-Ajayi, and Jason H. Moore. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 29: 359–73.

Risk Prediction: Methods, Challenges, and Opportunities. Li, Ruowang, Rui Duan, Lifang He, and Jason H. Moore. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 29: 650–53.

SynTwin: A Graph-Based Approach for Predicting Clinical Outcomes Using Digital Twins Derived From Synthetic Patients. Moore, Jason H., Xi Li, Jui-Hsuan Chang, Nicholas P. Tatonetti, Dan Theodorescu, Yong Chen, Folkert W. Asselbergs, Mythreye Venkatesan, and Zhiping Paul Wang. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 29: 96–107.

Detecting Goals of Care Conversations in Clinical Notes With Active Learning. Weissenbacher, Davy, Katherine Courtright, Siddharth Rawal, Andrew Crane-Droesch, Karen O’Connor, Nicholas Kuhl, Corinne Merlino, Anessa Foxwell, Lindsay Haines, Joseph Puhl, and Graciela Gonzalez-Hernandez. Journal of Biomedical Informatics, February, 104618.

Contralateral Suppression in Adrenal Venous Sampling Predicts Clinical and Biochemical Outcome in Primary Aldosteronism. Okubo, Jessica, Paula Frudit, Aline C. B. S. Cavalcante, Ana A. W. Maciel, Thais C. Freitas, Bruna Pilan, Gustavo F. C. Fagundes, Nara L. Queiroz, Matheo A. M. Stumpf, Victor C. M. Souza, Eduardo Z. Kawahara, Tatiana S. Goldbaum, Maria Adelaide A. Pereira, Vinicius F. Calsavara, Fernando M. A. Coelho, Vitor Srougi, Fabio Y. Tanno, Jose L. Chambo, Luiz A. Bortolotto, Luciano F. Drager, Maria Candida B. V. Fragoso, Ana Claudia Latronico, Berenice B. Mendonca, Francisco C. Carnevale, and Madson Q. Almeida. The Journal of Clinical Endocrinology and Metabolism, March, dgae142.

Regulation of Urea Cycle by Reversible High-Stoichiometry Lysine Succinylation. Zhang, Ran, Jingqi Fang, Xueshu Xie, Chris Carrico, Jesse G. Meyer, Lei Wei, Joanna Bons, Jacob Rose, Rebeccah Riley, Ryan Kwok, Prasanna Vadhana Ashok Kumaar, Yini Zhang, Wenjuan He, Yuya Nishida, Xiaojing Liu, Jason W. Locasale, Birgit Schilling, and Eric Verdin. Nature Metabolism, March.

Imaging

Impact of Cardiac Size on SPECT Myocardial Perfusion Imaging Performance: Insights From the REFINE-SPECT Registry. Randazzo, Michael J., Pierre Elias, Timothy J. Poterucha, Tali Sharir, Matthews B. Fish, Terrence D. Ruddy, Philipp A. Kaufmann, Albert J. Sinusas, Edward J. Miller, Timothy Bateman, Sharmila Dorbala, Marcelo Di Carli, Michelle Castillo, Joanna X. Liang, Robert J. H. Miller, Damini Dey, Daniel S. Berman, Piotr J. Slomka, and Andrew J. Einstein. European Heart Journal. Cardiovascular Imaging, March, jeae055.

Medicine

Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part II: Treatment Delivery for Non-Metastatic Biochemical Recurrence After Primary Radical Prostatectomy. Morgan, Todd M., Stephen A. Boorjian, Mark K. Buyyounouski, Brian F. Chapin, David Y. T. Chen, Heather H. Cheng, Roger Chou, Heather A. Jacene, Sophia C. Kamran, Sennett K. Kim, Erin Kirkby, Amy N. Luckenbaugh, Ben J. Nathanson, Yaw A. Nyame, Edwin M. Posadas, Phuoc T. Tran, and Ronald C. Chen. The Journal of Urology, February, 101097JU0000000000003891.

Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part III: Salvage Therapy After Radiotherapy or Focal Therapy, Pelvic Nodal Recurrence and Oligometastasis, and Future Directions. Morgan, Todd M., Stephen A. Boorjian, Mark K. Buyyounouski, Brian F. Chapin, David Y. T. Chen, Heather H. Cheng, Roger Chou, Heather A. Jacene, Sophia C. Kamran, Sennett K. Kim, Erin Kirkby, Amy N. Luckenbaugh, Ben J. Nathanson, Yaw A. Nyame, Edwin M. Posadas, Phuoc T. Tran, and Ronald C. Chen. The Journal of Urology, February, 101097JU0000000000003890.

Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part I: Introduction and Treatment Decision-Making at the Time of Suspected Biochemical Recurrence after Radical Prostatectomy. Morgan, Todd M., Stephen A. Boorjian, Mark K. Buyyounouski, Brian F. Chapin, David Y. T. Chen, Heather H. Cheng, Roger Chou, Heather A. Jacene, Sophia C. Kamran, Sennett K. Kim, Erin Kirkby, Amy N. Luckenbaugh, Ben J. Nathanson, Yaw A. Nyame, Edwin M. Posadas, Phuoc T. Tran, and Ronald C. Chen. The Journal of Urology, February, 101097JU0000000000003892.

Diagnostic and Prognostic Biomarkers of Chronic Pancreatitis: A Conceptual Framework Based on PRoBE Design. Yadav, Dhiraj, Darwin L. Conwell, Stephen J. Pandol, Hanno Steen, Ziding Feng, Liang Li, and Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Gastroenterology, February, S0016-5085(24)00236-1.

Pros of Inpatient SGLT-2 Inhibitor Use. Romo, Karina, and Roma Gianchandani. Endocrine Practice, February, S1530-891X(24)00067-3.

The Challenge of Regrowing Hair With Lasers in Androgenetic Alopecia. Juhasz, Margit L. W., Ella Csuka, Colin Kincaid, and Natasha Atanaskova Mesinkovska. Dermatologic Surgery, 50 (3): 303–6.

A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at Higher Risk for Developing Myeloid Malignancy. Lao, Zhentang, Ling-Wen Ding, Qiao-Yang Sun, Li Jia, Benedict Yan, Alvin Yu-Jin Ng, Sharah Mae Capinpin, Renwei Wang, Li Ying, Wee Joo Chng, H. Phillip Koeffler, Woon-Puay Koh, Jian-Min Yuan, Henry Yang, Yeow Tee Goh, and Nicholas Grigoropoulos. Clinical Cancer Research, March.

Medical Educators’ Perception of Race in Clinical Practice. Futterman, June, Catherine Bi, Brendan Crow, Sarah Kureshi, and Ebiere Okah. BMC Medical Education 24 (1): 230.

Medication-Related Osteonecrosis of the Jaw: Evolving Research for Multimodality Medical Management. Abdolrahmani, Ali, Joel B. Epstein, and Firoozeh Samim. Supportive Care in Cancer, 32 (4): 212.

Quality Indicators for Major Depressive Disorder in Adults: A Review of Performance Measures by the American College of Physicians. Qaseem, Amir, Rebecca A. Andrews, Karen Campos, Caroline L. Goldzweig, Scott MacDonald, Robert M. McLean, Rhea E. Powell, Nick Fitterman, and Performance Measurement Committee of the American College of Physicians*. Annals of Internal Medicine, March.

Neurology

Dementia Prevention and Treatment: A Narrative Review. Reuben, David B., Sarah Kremen, and Donovan T. Maust. JAMA Internal Medicine, March.

Neurosurgery

Encoding of Predictive Associations in Human Prefrontal and Medial Temporal Neurons During Pavlovian Appetitive Conditioning. Aquino, Tomas G., Hristos Courellis, Adam N. Mamelak, Ueli Rutishauser, and John P. O’Doherty. The Journal of Neuroscience, February, e1628232024.

A Contemporary Analysis of Surgical Ligation versus Endovascular Embolization in Patients With Intracranial Dural Arteriovenous Fistulas: A Propensity Score-Matched and Mixed-Effects Model Study. Shahrestani, Shane, Michelot Michel, Maria Paula Aguilera-Pena, Miguel D. Quintero-Consuegra, and Nestor R. Gonzalez. Neurosurgical Focus 56 (3): E3.

OBGYN

Healthcare Access Dimensions and Racial Disparities in End-of-Life Care Quality Among Ovarian Cancer Patients. Karanth, Shama, Oyomoare L. Osazuwa-Peters, Lauren E. Wilson, Rebecca A. Previs, Fariha Rahman, Bin Huang, Maria Pisu, Margaret Liang, Kevin C. Ward, Maria J. Schymura, Andrew Berchuck, and Tomi F. Akinyemiju. Cancer Research Communications, March.

Orthopaedics

Novel Bisphosphonate-Based Cathepsin K-Triggered Compound Targets the Enthesis Without Impairing Soft Tissue-to-Bone Healing. Shi, Brendan Y., Varun Sriram, Shannon Y. Wu, Dave Huang, Alexis Cheney, Melodie F. Metzger, Oskar Sundberg, Karen M. Lyons, Charles E. McKenna, Ichiro Nishimura, and Thomas J. Kremen. Frontiers in Bioengineering and Biotechnology 12: 1308161.

Contributions of the Abductor Muscles to Rotational and Distractive Stability of the Hip in a Biomechanical Cadaveric Model. Lim, Daniel P., Lionel E. Lazaro, Justin F. Kyhos, Michael M. Chau, Karen J. Ladnier, Trevor J. Nelson, Samuel A. Eberlein, Michael B. Banffy, and Melodie F. Metzger. Orthopaedic Journal of Sports Medicine 12 (3): 23259671241231984.

Pathology and Laboratory Medicine

Apolipoprotein E Is Enriched in Dense Deposits and Is a Marker for Dense Deposit Disease in C3 Glomerulopathy. Madden, Benjamin, Raman Deep Singh, Mark Haas, Lilian Mp Palma, Alok Sharma, Maria J. Vargas, LouAnn Gross, Vivian Negron, Torell Nate, M. Cristine Charlesworth, Jason D. Theis, Samih H. Nasr, Karl A. Nath, Fernando C. Fervenza, and Sanjeev Sethi. Kidney International, March, S0085-2538(24)00169-8.

Pediatrics

Comparison of Estimated GFR Using Cystatin C Versus Creatinine in Pediatric Kidney Transplant Recipients. Pizzo, Helen, John Nguyen, George J. Schwartz, Katherine Wesseling-Perry, Robert Ettenger, Eileen Tsai Chambers, and Patricia Weng. Pediatric Nephrology (Berlin, Germany), March.

Surgery

The Utility and Accuracy of ChatGPT in Providing Post-Operative Instructions Following Tonsillectomy: A Pilot Study. Dhar, Sarit, Dhruv Kothari, Missael Vasquez, Travis Clarke, Andrew Maroda, Wade G. McClain, Anthony Sheyn, Robert M. Tuliszewski, Dennis M. Tang, and Sanjeet V. Rangarajan. International Journal of Pediatric Otorhinolaryngology 179 (February): 111901.

A Multi-Institutional Study Comparing Stoma Location in Neonates With Intestinal Perforation. Chen, Stephanie Y., Gabriella Grisotti, Shale J. Mack, Ashley E. Walther, Rachel L. Chapman, Richard A. Falcone, and Eugene S. Kim. The Journal of Surgical Research 297 (March): 56–62.

ASO Visual Abstract: A Prospective Study of Sentinel Node Biopsy Omission in Women Age ? 65 With ER+ Breast Cancer. Chung, Alice P., Catherine M. Dang, Scott R. Karlan, Farin F. Amersi, Edward M. Phillips, Marissa K. Boyle, Yujie Cui, and Armando E. Giuliano. Annals of Surgical Oncology, March.

Urology

Clinical Applications of Artificial Intelligence in Robotic Surgery. Knudsen, J. Everett, Umar Ghaffar, Runzhuo Ma, and Andrew J. Hung. Journal of Robotic Surgery 18 (1): 102.

Himplant® Subcutaneous Penile Implant Improves Penile Appearance and Erectile Dysfunction After Radical Prostatectomy: A Case Series. Valenzuela, Robert J., James J. Elist, Daniel Moon, Luka Cvijanovic, and Steven K. Wilson. International Journal of Impotence Research, March.