A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug. 3-10.
Cardiology
A Pharmacologic Update: New Treatments for Patients With Cardiovascular Disease. Radchik, Elizabeth, Leslie L. Davis, and Ciantel A. Blyler. The Nursing Clinics of North America 58 (3): 389–403.
Heart Failure Hospitalizations Versus Cardiovascular Mortality in Heart Failure Trials. Kaul, Sanjay, Tariq Jamal Siddiqi, Stefan D. Anker, and Javed Butler. The American Journal of Cardiology, August, S0002-9149(23)00596-9.
Peptidyl Arginine Deiminase Inhibition Alleviates Angiotensin II-Induced Fibrosis. Ijichi, Takeshi, Niveda Sundararaman, Thomas G. Martin, Rakhi Pandey, Etai Koronyo, Jonathan A. Kirk, Eduardo Marbán, Jennifer E. Van Eyk, and Justyna Fert-Bober. American Journal of Translational Research 15 (7): 4558–72.
Encapsulated Calcified Hematoma Mimicking a Cardiac Tumor, Diagnosed 25 Years Post-Traumatic Injury. Anderson, Lauren R., Jairo Aldana-Bitar, Venkat Sanjay Manubolu, Dhiran Verghese, Luay Alalawi, Noah R. Ramirez, Matthew J. Budoff, and Ronald P. Karlsberg. JACC. Case Reports 18 (July): 101917.
*Expert Systematic Review on the Choice of Conduits for Coronary Artery Bypass Grafting: Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and The Society of Thoracic Surgeons (STS). Gaudino, Mario, Faisal G. Bakaeen, Sigrid Sandner, Gabriel S. Aldea, Hirokuni Arai, Joanna Chikwe, Scott Firestone, Stephen E. Fremes, Walter J. Gomes, Ki Bong-Kim, Kalie Kisson, Paul Kurlansky, Jennifer Lawton, Daniel Navia, John D. Puskas, Marc Ruel, Joseph F. Sabik, Thomas A. Schwann, David P. Taggart, James Tatoulis, and Moritz Wyler von Ballmoos. The Journal of Thoracic and Cardiovascular Surgery, July, S0022-5223(23)00544-5.
*Expert Systematic Review on the Choice of Conduits for Coronary Artery Bypass Grafting: Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and The Society of Thoracic Surgeons (STS). Gaudino, Mario, Faisal G. Bakaeen, Sigrid Sandner, Gabriel S. Aldea, Hirokuni Arai, Joanna Chikwe, Scott Firestone, Stephen E. Fremes, Walter J. Gomes, Ki Bong-Kim, Kalie Kisson, Paul Kurlansky, Jennifer Lawton, Daniel Navia, John D. Puskas, Marc Ruel, Joseph F. Sabik, Thomas A. Schwann, David P. Taggart, James Tatoulis, and Moritz Wyler von Ballmoos. The Annals of Thoracic Surgery, July, S0003-4975(23)00673-2.
*Expert Systematic Review on the Choice of Conduits for Coronary Artery Bypass Grafting: Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and The Society of Thoracic Surgeons (STS). Gaudino, Mario, Faisal G. Bakaeen, Sigrid Sandner, Gabriel S. Aldea, Hirokuni Arai, Joanna Chikwe, Scott Firestone, Stephen E. Fremes, Walter J. Gomes, Ki Bong-Kim, Kalie Kisson, Paul Kurlansky, Jennifer Lawton, Daniel Navia, John D. Puskas, Marc Ruel, Joseph F. Sabik, Thomas A. Schwann, David P. Taggart, James Tatoulis, and Moritz Wyler von Ballmoos. European Journal of Cardio-Thoracic Surgery: Official Journal of the European Association for Cardio-Thoracic Surgery 64 (2): ezad163.
*This article has been co-published with permission in the European Journal of Cardio-Thoracic Surgery, The Annals of Thoracic Surgery, and the Journal of Thoracic and Cardiovascular Surgery.
Computational Biomedicine
A Data-Driven Analysis of Ward Capacity Strain Metrics That Predict Clinical Outcomes Among Survivors of Acute Respiratory Failure. Kohn, Rachel, Michael O. Harhay, Gary E. Weissman, Ryan Urbanowicz, Wei Wang, George L. Anesi, Stefania Scott, Brian Bayes, S. Ryan Greysen, Scott D. Halpern, and Meeta Prasad Kerlin. Journal of Medical Systems 47 (1): 83.
Natural Language Processing Can Automate Extraction of Barrett’s Esophagus Endoscopy Quality Metrics. Soroush, Ali, Courtney J. Diamond, Haley M. Zylberberg, Benjamin May, Nicholas Tatonetti, Julian A. Abrams, and Chunhua Weng. MedRxiv: The Preprint Server for Health Sciences, July,07.11.23292529.
Medicine
Comparing the Safety Action Feedback and Engagement (SAFE) Loop With an Established Incident Reporting System: Study Protocol for a Pragmatic Cluster Randomized Controlled Trial. Berdahl, Carl T., Andrew J. Henreid, Tara N. Cohen, Bernice L. Coleman, Edward G. Seferian, Donna Leang, Sungjin Kim, Marcio A. Diniz, Matthew Grissinger, Karen Kaiser, Sara McCleskey, Xi Zhu, and Teryl K. Nuckols. Contemporary Clinical Trials Communications 35 (October): 101192.
Postvaccination Symptoms After SARS-CoV-2 MRNA Vaccination Among Patients with Inflammatory Bowel Disease: A Prospective, Comparative Study. Mujukian, Angela, Rashmi Kumar, Dalin Li, Philip Debbas, Gregory J. Botwin, Susan Cheng, Joseph Ebinger, Jonathan Braun, Dermot McGovern, Gil Y. Melmed, and CORALE-IBD Study Group. Inflammatory Bowel Diseases, August, izad114.
Methods for Estimating Insulin Resistance From Untargeted Metabolomics Data. Hsu, Fang-Chi, Nicholette D. Palmer, Shyh-Huei Chen, Maggie C. Y. Ng, Mark O. Goodarzi, Jerome I. Rotter, Lynne E. Wagenknecht, Michael P. Bancks, Richard N. Bergman, and Donald W. Bowden. Metabolomics, 19 (8): 72.
Posaconazole and Risk of Cutaneous Squamous Cell Carcinoma After Lung Transplantation: A Single Institution, Retrospective Cohort Study. Kuklinski, Lawrence F., Alexandra M. Klomhaus, Amy Shen, Natalie Achamallah, Teresa T. Soriano, Rajan Saggar, and Stephen S. Weigt. Archives of Dermatological Research, August.
Racial Variation in Healthcare Resource Utilization and Expenditures in Knee/Hip Osteoarthritis Patients: A Retrospective Analysis of a Medicaid Population. Silverman, Stuart, Elizabeth Packnett, Anthony Zagar, Sheena Thakkar, Patricia Schepman, Warachal Faison, Cory Hultman, Nicole M. Zimmerman, and Rebecca L. Robinson. Journal of Medical Economics, August, 1–15.
Loss of Pkd1 Limits Susceptibility to Colitis and Colorectal Cancer. Nikonova, Anna S., Alexander Y. Deneka, Flaviane N. Silva, Shabnam Pirestani, Rossella Tricarico, Anna A. Kiseleva, Yan Zhou, Emmanuelle Nicolas, Douglas B. Flieder, Sergei I. Grivennikov, and Erica A. Golemis. Oncogenesis 12 (1): 40.
Characteristics and Predictors Associated With Cancer-Related Fatigue Among Solid and Liquid Tumors. Satheeshkumar, Poolakkad S., Roberto Pili, Joel B. Epstein, Sudheer B. Kurunthatil Thazhe, Rhine Sukumar, and Minu Ponnamma Mohan. Journal of Cancer Research and Clinical Oncology, August.
An Individualized Approach to the Management of Cushing Disease. Fleseriu, Maria, Elena V. Varlamov, Jose M. Hinojosa-Amaya, Fabienne Langlois, and Shlomo Melmed. Nature Reviews. Endocrinology, August.
Lung Transplant From COVID-19 Positive Donors: Cautiously Optimistic. Zaffiri, Lorenzo, and Cameron R. Wolfe. The Annals of Thoracic Surgery, August, S0003-4975(23)00817-2.
Can Deep Learning Detect Incidental Abnormal Cardiac Uptake Related to Amyloidosis on Routine Bone Scintigraphy? Slomka, Piotr J., and Robert J. H. Miller. JACC. Cardiovascular Imaging 16 (8): 1096–98.
Osler’s Nodes in Infective Endocarditis. Zamora Gonzalez, Rolando A., and Lena J. Heung. IDCases 33: e01862.
Neurosurgery
?-Amyloid Targeting Nanodrug for Neuron-Specific Delivery of Nucleic Acids in Alzheimer’s Disease Mouse Models. Israel, Liron L., Tao Sun, Oliver Braubach, Alysia Cox, Ekaterina S. Shatalova, Harun-Mohammad Rashid, Anna Galstyan, Zachary Grodzinski, Xue Ying Song, Oksana Chepurna, Vladimir A. Ljubimov, Antonella Chiechi, Sachin Sharma, Connor Phebus, Yizhou Wang, Julia Y. Ljubimova, Keith L. Black, and Eggehard Holler. Journal of Controlled Release, August, S0168-3659(23)00497-2.
Nursing
Medically Ready for Discharge: A Multisite ‘Point-in-Time’ Assessment of Hospitalized Patients. Bann, Maralyssa, Nicholas Meo, J. P. Lopez, Amy Ou, Molly Rosenthal, Hussain Khawaja, Leigh A. Goodman, Melanie Barone, Bernice Coleman, Heidi J. High, Lori Overbeek, Pam Shelbourn, Lisa VerMaas, Amy Baughman, Adith Sekaran, Rachel Cyrus, Nathan O’Dorisio, Lane Beatty, Silvia Loica-Mersa, Alan Kubey, Rebecca Jaffe, Chad Vokoun, Kwame Koom-Dadzie, Kencee Graves, Matthew Tuck, and Paul Helgerson. Journal of Hospital Medicine, August.
OBGYN
The POCKET Study: Personal-Device-Based Point-of-Care-Ultrasound Versus Standard Ultrasound Machine Use for Inpatient Obstetric Workflow: A Time and Motion Study. Leggett, Cecilia B., Tara Cohen, Erica Sauro, and Melissa S. Wong. American Journal of Obstetrics & Gynecology MFM, August, 101100.
Orthopaedics
Do Peri-Operative Parathyroid Hormone (PTH) Analogues Improve Bone Density and Decrease Mechanical Complications in Spinal Deformity Correction?-A Minimum 2-Year Radiological Study Measuring Hounsfield Units. Chung, Andrew, Jerry Robinson, David Gendelberg, Jose Jimenez, Anita Anand, Arya Rao, Babak Khandehroo, Sheila Kahwaty, and Neel Anand. European Spine Journal, August.
Racial and Ethnic Disparities in Pediatric Musculoskeletal Care. Sborov, Katherine D., Lee S. Haruno, Samuel Raszka, and Selina C. Poon. Current Reviews in Musculoskeletal Medicine, August.
Pathology
The Genetic Landscape of Fibroepithelial Lesions of the Breast. Dadmanesh, Farnaz, Xiaomo Li, Matthew Leong, Horacio Maluf, and Bonnie Balzer. Advances in Anatomic Pathology, August.
Standardized Classification of Lung Adenocarcinoma Subtypes and Improvement of Grading Assessment Through Deep Learning. Lami, Kris, Noriaki Ota, Shinsuke Yamaoka, Andrey Bychkov, Keitaro Matsumoto, Wataru Uegami, Jijgee Munkhdelger, Kurumi Seki, Odsuren Sukhbaatar, Richard Attanoos, Sabina Berezowska, Luka Brcic, Alberto Cavazza, John C. English, Alexandre Todorovic Fabro, Kaori Ishida, Yukio Kashima, Yuka Kitamura, Brandon T. Larsen, Alberto M. Marchevsky, Takuro Miyazaki, Shimpei Morimoto, Mutsumi Ozasa, Anja C. Roden, Frank Schneider, Maxwell L. Smith, Kazuhiro Tabata, Angela M. Takano, Tomonori Tanaka, Tomoshi Tsuchiya, Takeshi Nagayasu, Hidenori Sakanashi, and Junya Fukuoka. The American Journal of Pathology, August, S0002-9440(23)00273-0.
Demographic Patterns and Clinicopathological Analysis of Sarcomatoid Renal Cell Carcinoma in US Population. Ullah, Asad, Abdul Qahar Khan Yasinzai, Om V. Sakhalkar, Kue Tylor Lee, Imran Khan, Bisma Tareen, Agha Wali, Abdul Waheed, Jaffar Khan, Gul Andam, Kaleemullah Kakar, Saleh Heneidi, and Nabin R. Karki. Clinical Genitourinary Cancer, July, S1558-7673(23)00179-9.
Pediatrics
Revision Tracheotomy Complicated by History of Follicular B-Cell Lymphoma. Ustrell, Sarah, Jordan K. Simmons, Garrett Henkle, and Adam R. Szymanowski. Ear, Nose, & Throat Journal, August, 1455613231189229.
Radiation Oncology
External Validation of Cardiac Disease, Hypertension, and Logarithmic Left Anterior Descending Coronary Artery Radiation Dose (CHyLL) for Predicting Major Adverse Cardiac Events after Lung Cancer Radiotherapy. Tjong, M. C., S. C. Zhang, J. O. Gasho, K. D. Silos, C. Gay, E. M. McKenzie, J. Steers, D. S. Bitterman, A. P. Nikolova, A. Nohria, U. Hoffmann, K. D. Brantley, R. H. Mak, and K. M. Atkins. Clinical and Translational Radiation Oncology 42 (September): 100660.
Surgery
What Is the Role of Lymph Node Resections in Small Islet Tumors? Gangi, Alexandra, and Cristina R. Ferrone. Advances in Surgery 57 (1): 47–58.
Management of a Complex Case of a Recurrent Paraganglioma. Petrovic, Masa, Michela Borrelli, and Jack A. Shohet. Ear, Nose, & Throat Journal, August, 1455613231187762.
Cogan Syndrome: A Case Study and Review of the Literature. Nasrollahi, Tasha, Michela Borrelli, Harrison W. Lin, and Hamid R. Djalilian. Ear, Nose, & Throat Journal, August, 1455613231187765.
ASO Visual Abstract: Impact of Postoperative, Antibiotic Prophylaxis on Surgical Site Infection Rates After Mastectomy With Drains but Without Immediate Reconstruction-A Multicenter, Double-Blinded, Randomized, Control Superiority Trial. Sattar, Abida K., Taleaa Masroor, Russell Seth Martins, Nida Zahid, Hania Shahzad, Rufina Soomro, Omema Saleem, Lubna M. Vohra, Sana Zeeshan, Muhammad Areeb Ashfaq, Irum Khan, Rida Nadeem, Nikhat Fatima, Ayisha Afzal Qureshi, Farin F. Amersi, and Syed Faisal Mahmood. Annals of Surgical Oncology, August.
ASO Visual Abstract: Changes in Surgical Management of the Axilla Over 11 Years-Report on Over 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial. Boughey, Judy C., Hongmei Yu, Catherine Lu Dugan, Mara A. Piltin, Lauren Postlewait, Jennifer D. Son, Kirsten K. Edmiston, Constantine Godellas, Marie C. Lee, Michael J. Carr, Jennifer E. Tonneson, Angelena Crown, Rachel B. Lancaster, Hannah E. Woriax, Cheryl A. Ewing, Harrison S. Chau, Anne K. Patterson, Jasmine M. Wong, Michael D. Alvarado, Rachel L. Yang, Theresa W. Chan, Jori B. Sheade, Gretchen M. Ahrendt, Kelsey E. Larson, Kayla Switalla, Todd M. Tuttle, Julia C. Tchou, Roshni Rao, Nina Tamirisa, Puneet Singh, Rebekah E. Gould, Alicia Terando, Candice Sauder, Kelly Hewitt, Akiko Chiba, Laura J. Esserman, and Rita Mukhtar. Annals of Surgical Oncology, August.
Prospective, Randomized, Double-Blind Phase 2B Trial of the TLPO and TLPLDC Vaccines to Prevent Recurrence of Resected Stage III/IV Melanoma: A Prespecified 36-Month Analysis. Carpenter, Elizabeth Lee, Spencer Van Decar, Alexandra M. Adams, Anne E. O’Shea, Patrick McCarthy, Robert Connor Chick, Guy Travis Clifton, Timothy Vreeland, Franklin A. Valdera, Ankur Tiwari, Diane Hale, Phillip Kemp Bohan, Annelies Hickerson, Todd Smolinsky, Katryna Thomas, Jessica Cindass, John Hyngstrom, Adam C. Berger, James Jakub, Jeffrey J. Sussman, Montaser F. Shaheen, Xianzhong Yu, Thomas E. Wagner, Mark Faries, and George E. Peoples. Journal for Immunotherapy of Cancer 11 (8): e006665.
How Do We PI? Results of an EAST Quality, Patient Safety, and Outcomes Survey. Horwitz, Daniel, Ryan Peter Dumas, Kyle Cunningham, Carlos H. Palacio, Daniel R. Margulies, Christine Eme, and Marko Bukur. Trauma Surgery & Acute Care Open 8 (1): e001059.