This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Aug.10-17.

Biomedical Sciences

Longitudinal Developmental Trajectories of Functional Connectivity Reveal Regional Distribution of Distinct Age Effects in Infancy. Liu, Janelle, Haitao Chen, Emil Cornea, John H. Gilmore, and Wei Gao. Cerebral Cortex (New York, N.Y.: 1991), August, bhad288.

Atorvastatin Lowers 68Ga-DOTATATE Uptake in Coronary Arteries, Bone Marrow and Spleen in Individuals With Type 2 Diabetes. Oostveen, Reindert F., Yannick Kaiser, Mia R. Ståhle, Nick S. Nurmohamed, Evangelos Tzolos, Marc R. Dweck, Jeffrey Kroon, Andrew J. Murphy, Damini Dey, Piotr J. Slomka, Hein J. Verberne, Erik S. G. Stroes, and Nordin M. J. Hanssen. Diabetologia, August.

A Sex-Specific Thermogenic Neurocircuit Induced by Predator Smell Recruiting Cholecystokinin Neurons in the Dorsomedial Hypothalamus. Jovanovic, Predrag, Allan-Hermann Pool, Nancy Morones, Yidan Wang, Edward Novinbakht, Nareg Keshishian, Kaitlyn Jang, Yuki Oka, and Celine E. Riera. Nature Communications 14 (1): 4937.

Physics-Informed Deep Learning for T2-Deblurred Superresolution Turbo Spin Echo MRI. Chen, Zihao, Margaret Caroline Stapleton, Yibin Xie, Debiao Li, Yijen L. Wu, and Anthony G. Christodoulou. Magnetic Resonance in Medicine, August.

Complement C1q Essential for Aeroallergen Sensitization via CSF1R+ Conventional Dendritic Cells Type-2. Moon, Hyung-Geun, Jacob D. Eccles, Seung-Jae Kim, Ki-Hyun Kim, Young-Mee Kim, Jalees Rehman, Hyun Lee, Pinal Kanabar, John W. Christman, Steven J. Ackerman, Christian Ascoli, Homan Kang, Hak Soo Choi, Minhyung Kim, Sungyong You, and Gye Young Park. The Journal of Allergy and Clinical Immunology, August, S0091-6749(23)00983-1.

Female Patients Delay Seeking Medical Care With Alcohol-Associated Acute Pancreatitis. Jeon, Christie Y., Esther Adeniran, Connor Stewart, Georgios I. Papachristou, Joseph R. Pisegna, Alma A. Kuc, James L. Buxbaum, Stephen J. Pandol, and Dhiraj Yadav. Pancreatology, August, S1424-3903(23)01605-8.

Interactome Profiling of DNA Damage Response (DDR) Mediators With Immunoprecipitation-Mass Spectrometry. Law, Henry C.-H., Dragana Noe, and Nicholas T. Woods. Methods in Molecular Biology (Clifton, N.J.) 2701: 185–97.

Cardiac Surgery

Repeat Pediatric Heart Transplantation: A United Network for Organ Sharing Database Analysis. Rowe, Georgina, George Gill, M. Mujeeb Zubair, Qiudong Chen, Jason Thomas, Shrishiv A. Timbalia, Asishana A. Osho, Dominic Emerson, Richard Kim, Michael E. Bowdish, Joanna Chikwe, and Joseph W. Turek. Clinical Transplantation, August, e15073.

Understanding Aortic Disease: Why We Really Need Big Data. Brennan, Zachary, and Michael E. Bowdish. The Annals of Thoracic Surgery, August, S0003-4975(23)00846-9.

Evaluating the Ladder of Temporary Mechanical Support. Emerson, Dominic, and Pedro Catarino. The Annals of Thoracic Surgery, August, S0003-4975(23)00829-9.

Cardiology

Risk of Arrhythmic Death in Patients With Nonischemic Cardiomyopathy: JACC Review Topic of the Week. Chrispin, Jonathan, Faisal M. Merchant, Neal K. Lakdawala, Katherine C. Wu, Gordon F. Tomaselli, Rachita Navara, Estelle Torbey, Amrut V. Ambardekar, Rajesh Kabra, Eloisa Arbustini, Jagat Narula, Maya Guglin, Christine M. Albert, Sumeet S. Chugh, Natalia Trayanova, and Jim W. Cheung. Journal of the American College of Cardiology 82 (8): 735–47.

3-Year Follow-up of a Prospective, Multicenter Study of the Amplatzer Piccolo^TM Occluder for Transcatheter Patent Ductus Arteriosus Closure in Children ??700 Grams. Morray, Brian H., Shyam K. Sathanandam, Thomas Forbes, Matthew Gillespie, Darren Berman, Aimee K. Armstrong, Shabana Shahanavaz, Thomas Jones, Toby Rockefeller, Henri Justino, David Nykanen, Courtney Weiler, Dan Gutfinger, and Evan M. Zahn. Journal of Perinatology, August.

Kidney Function Monitoring and Trajectories in Patients With Atrial Fibrillation. Hawkins, Nathaniel M., Natasha Wiebe, Jason G. Andrade, Roopinder K. Sandhu, Justin A. Ezekowitz, Padma Kaul, Marcello Tonelli, and Finlay A. McAlister. Clinical and Experimental Nephrology, August.

Two Negatives Make a Positive: Maximizing Heart Procurement in Adult Congenital Heart Disease. Peled, Yael, and Michelle M. Kittleson. The Journal of Heart and Lung, August, S1053-2498(23)01965-4.

Neutralization of SARS-CoV-2 Variants Elicited by the Combination of Vaccination and Natural Infection in Heart Transplant Recipients. Peled, Yael, Arnon Afek, Jignesh K. Patel, Ehud Raanani, Amit Segev, Eilon Ram, Nofar Atari, Limor Kliker, Bayan Abd Elkader, and Michal Mandelboim. Clinical Transplantation, August, e15092.

DNA Methylation Networks Underlying Mammalian Traits. Haghani, Amin, Caesar Z. Li, Todd R. Robeck, Joshua Zhang, Ake T. Lu, Julia Ablaeva, Victoria A. Acosta-Rodríguez, Danielle M. Adams, Abdulaziz N. Alagaili, Javier Almunia, Ajoy Aloysius, Nabil M. S. Amor, Steve Horvath, et al. Science (New York, N.Y.) 381 (6658): eabq5693.

Microvascular Aging and Eicosanoids-Women’s Evaluation of Systemic Aging Tenacity (‘You Are Never Too Old to Become Younger!’) Specialized Center of Research Excellence on Sex Differences Career Enhancement Core: Building the Future. Pevnick, Joshua M., Marcio A. Diniz, Denis Magoffin, Mariko Ishimori, and C. Noel Bairey Merz. Journal of Women’s Health (2002) 32 (8): 883–90.

Imaging

Optimal Dose Determination for Coronary Artery Calcium Scoring CT at Standard Tube Voltage. Zhou, Yifang, Emi Eastman, Christina Lee, and Alexander Scott. European Journal of Radiology 167 (August): 111029.

Interplay Between Zero CAC, Quantitative Plaque Analysis, and Adverse Events in a Diverse Patient Cohort. Fattouh, Michael, Toshiki Kuno, Pamela Pina, John P. Skendelas, Daniel Lorenzatti, Javier Arce, Jonathan Daich, Gustavo Duarte, Carol Fernandez-Hazim, Miguel Rodriguez-Guerra, Patrick Neshiwat, Aldo L. Schenone, Lili Zhang, Carlos J. Rodriguez, Armin Arbab-Zadeh, Piotr J. Slomka, Salim S. Virani, Michael J. Blaha, Daniel S. Berman, Damini Dey, Mario J. Garcia, and Leandro Slipczuk. Circulation. Cardiovascular Imaging 16 (8): e015236.

Medicine

Coronavirus Disease 2019 (COVID-19) Pandemic Lifestyle Changes May Have Influenced Small Bowel Microbial Composition and Microbial Resistance. Hosseini, Ava, Mohamad Rashid, Gabriela Leite, Gillian M. Barlow, Gonzalo Parodi, Maritza Sanchez, Sarah Ayyad, Maya L. Pimentel, Walter Morales, Stacy Weitsman, Mark Pimentel, and Ruchi Mathur. Digestive Diseases and Sciences, August.

Key Device Attributes for Injectable Somatostatin Receptor Ligand Therapy in Acromegaly and Neuroendocrine Tumours. Jørgensen, Jens Otto L., Wouter W. de Herder, Wendy A. Martin, Teodora Kolarova, Muriël Marks, Cecilia Follin, Wanda Geilvoet, and Shlomo Melmed. Advances in Therapy, August.

Hepatocellular Carcinoma Surveillance Patterns and Outcomes in Patients With Cirrhosis. Daher, Darine, Karim Seif El Dahan, Alva Cano, Michael Gonzalez, Crystal Ransom, Erik Jaurez, Osiris Carranza, Lisa Quirk, Todd Morgan, Purva Gopal, Madhukar S. Patel, Sarah Lieber, Jeremy Louissaint, Thomas Cotter, Lisa B. VanWagner, Ju Dong Yang, Neehar D. Parikh, Adam Yopp, Nicole E. Rich, and Amit G. Singal. Clinical Gastroenterology and Hepatology, August, S1542-3565(23)00625-0.

Pembrolizumab in Patients with Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study. Duvivier, Herbert L., Michael Rothe, Pam K. Mangat, Elizabeth Garrett-Mayer, Eugene R. Ahn, Tareq Al Baghdadi, Ajjai S. Alva, Stephanie A. Dublis, Timothy L. Cannon, Carmen J. Calfa, Rui Li, Deepti Behl, Vi K. Chiu, Philip J. Gold, Alissa S. Marr, Kathryn F. Mileham, Steven Francis Powell, Jordi Rodon, Ramya Thota, Gina N. Grantham, Abigail Gregory, Dominique C. Hinshaw, Susan Halabi, and Richard L. Schilsky. Journal of Clinical Oncology, August, JCO2300702.

Immunotherapy and Transarterial Radioembolization Combination Treatment for Advanced Hepatocellular Carcinoma. Yeo, Yee Hui, Jeff Liang, Marie Lauzon, Michael Luu, Mazen Noureddin, Walid Ayoub, Alexander Kuo, Kamya Sankar, Jun Gong, Andrew Hendifar, Arsen Osipov, Marc L. Friedman, H. Gabriel Lipshutz, Jonathan Steinberger, Kambiz Kosari, Nicholas Nissen, Ghassan K. Abou-Alfa, Amit G. Singal, and Ju Dong Yang. The American Journal of Gastroenterology, August.

Associations Between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis (MESA). Wood, Alexis C., Mark O. Goodarzi, Mackenzie K. Senn, Meghana D. Gadgil, Goncalo Graca, Matthew A. Allison, Ioanna Tzoulaki, Michael Y. Mi, Philip Greenland, Timothy Ebbels, Paul Elliott, Russell P. Tracy, David M. Herrington, and Jerome I. Rotter. The Journal of Nutrition, August, S0022-3166(23)72522-4.

Inflammasome-Independent Roles of NLR and ALR Family Members. Gupta, Suman, Suzanne L. Cassel, and Fayyaz S. Sutterwala. Methods in Molecular Biology (Clifton, N.J.) 2696: 29–45.

Neurology

Intersite Brain MRI Volumetric Biases Persist Even in a Harmonized Multisubject Study of Multiple Sclerosis. Clark, Kelly A., Carly M. O’Donnell, Mark A. Elliott, Shahamat Tauhid, Blake E. Dewey, Renxin Chu, Samar Khalil, Govind Nair, Pascal Sati, Anna DuVal, Nicole Pellegrini, Amit Bar-Or, Clyde Markowitz, Matthew K. Schindler, Jonathan Zurawski, Peter A. Calabresi, Daniel S. Reich, Rohit Bakshi, Russell T. Shinohara, and NAIMS Cooperative. Journal of Neuroimaging, August.

OBGYN

Molecular Mechanisms of Multi-Omic Regulation in Breast Cancer. Ochoa, Soledad, and Enrique Hernández-Lemus. Frontiers in Oncology 13: 1148861.

Expanding Research on the Impact of Financial Hardship on Emotional Well-Being: Guidance of Diverse Stakeholders to the Emotional Well-Being and Economic Burden of Disease (EMOT-ECON) Research Network. Pisu, Maria, Margaret I. Liang, Sarah D. Pressman, Carol D. Ryff, Minal R. Patel, Mustafa Hussein, Courtney P. Williams, Nora B. Henrikson, Yu-Mei Schoenberger, Laurel J. Pracht, Erin Bradshaw, Terrell Terri Carpenter, Amy Matthis, David L. Schwartz, and Michelle Y. Martin. Frontiers in Psychology 14: 1196525.

Orthopaedics

Limb Position Affects Intraoperative Assessment of Condylar Width. Tucker, Douglass W., Michael J. Chen, Akhil Reddy, John J. Carney, Michael J. Gardner, and Geoffrey S. Marecek. European Journal of Orthopaedic Surgery & Traumatology: Orthopedie Traumatologie, August.

Pathology

Methods to Measure NLR Oligomerization I: Size Exclusion Chromatography, Co-Immunoprecipitation, and Cross-Linking. Khare, Sonal, Savita Devi, Alexander D. Radian, Andrea Dorfleutner, and Christian Stehlik. Methods in Molecular Biology (Clifton, N.J.) 2696: 55–71.

Pediatrics 

Development of an Equity, Diversity, and Inclusion Committee for a Collaborative Quality Improvement Network: Pediatric Cardiac Critical Care Consortium (PC4) Equity, Diversity and Inclusion (EDI) Committee: White Paper 2023. Tjoeng, Yuen Lie, David K. Werho, Claudia Algaze, Pooja Nawathe, Solange Benjamin, Kurt R. Schumacher, and Titus Chan. Cardiology in the Young, August, 1–7.

A Near Miss of a Retropharyngeal Abscess With MRSA in a 5-Week-Old Boy Due to an Unusual Presentation. Bastien, Amanda J., Gene C. Liu, Dennis M. Tang, Abhita Reddy, Kyohei Itamura, Jack Green, and Priya R. Soni. Klimik Dergisi/Klimik Journal, July 1–6.

Editorial: Recent Advances in Pediatric Inflammatory Diseases. Kocatürk, Begüm, Füsun Özmen, Moshe Arditi, and Seza Özen. Frontiers in Pediatrics 11: 1237625.

Radiation Oncology

Impact of the Acuros XB Spatial Discretization Error on ArcCHECK VMAT QA for Small-Field SBRT. He, Chuan, Ankit Pant, and Anh H. Le. Journal of Applied Clinical Medical Physics, August, e14100.

Surgery

Predictors of Fetal Delivery in Pregnant Trauma Patients: A Multicenter Study. Santos, Jeffrey W., Areg Grigorian, Alexa N. Lucas, Nicole Fierro, Navpreet K. Dhillon, Eric J. Ley, Jennifer Smith, Sigrid Burruss, Alden Dahan, Arianne Johnson, William Ganske, Walter L. Biffl, Dunya Bayat, Matthew Castelo, Diane Wintz, Kathryn B. Schaffer, Dennis J. Zheng, Areti Tillou, Raul Coimbra, Rahul Tuli, Jarrett E. Santorelli, Brent Emigh, Morgan Schellenberg, Kenji Inaba, Thomas K. Duncan, Graal Diaz, Erika Tay-Lasso, Danielle C. Zezoff, and Jeffry Nahmias. The Journal of Trauma and Acute Care Surgery, August.

Systemic Therapy for Melanoma: ASCO Guideline Update. Seth, Rahul, Sanjiv S. Agarwala, Hans Messersmith, Krishna C. Alluri, Paolo A. Ascierto, Michael B. Atkins, Kathryn Bollin, Matias Chacon, Nancy Davis, Mark B. Faries, Pauline Funchain, Jason S. Gold, Samantha Guild, David E. Gyorki, Varinder Kaur, Nikhil I. Khushalani, John M. Kirkwood, Jennifer Leigh McQuade, Michael O. Meyers, Anthony Provenzano, Caroline Robert, Mario Santinami, Amikar Sehdev, Vernon K. Sondak, Gilliosa Spurrier, Umang Swami, Thach-Giao Truong, Katy K. Tsai, Alexander van Akkooi, and Jeffrey Weber. Journal of Clinical Oncology, August, JCO2301136.

An Endoscopic Endonasal Attempt at Pediatric Meningoencephalocele Repair. Raskin, Jonathan, Michela Borrelli, and Bozena Wrobel. Ear, Nose, & Throat Journal, August, 1455613231187760.

BNT162b2-Vaccine-Induced Neutralization Responses Are Immune Correlates of Clinical Protection against SARS-CoV-2 in Heart Transplant Recipients. Peled, Yael, Jignesh K. Patel, Ehud Raanani, Ram Eilon, Alexander Fardman, Roy Beigel, Nofar Atari, Limor Kliker, Bayan Abd Elkader, Michal Mandelboim, and Arnon Afek. Clinical Transplantation, August, e15091.

Optimization of Diagnostic and Procedural Codes to Identify Patients With Acute Invasive Fungal Sinusitis. Munyemana, Marie-Ange, Omar G. Ahmed, Mas Takashima, Aatin K. Dhanda, Dennis Tang, Arthur Wu, Matthew J. Wu, Dorina Kallogjeri, Jay F. Piccirillo, and Lauren T. Roland. International Forum of Allergy & Rhinology, August.

Urology

The Growing Implications of Obesity for Prostate Cancer Risk and Mortality: Where Do We Go From Here? Daniels, James Percy, Stephen J. Freedland, and Gillian Gresham. Journal of the National Cancer Institute, August, djad140.