This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published April 13-20.

Biomedical Sciences

Human IPSC-Derived Neural Progenitor Cells Secreting GDNF Provide Protection in Rodent Models of ALS and Retinal Degeneration. Laperle, Alexander H., V. Alexandra Moser, Pablo Avalos, Bin Lu, Amanda Wu, Aaron Fulton, Stephany Ramirez, Veronica J. Garcia, Shaughn Bell, Ritchie Ho, George Lawless, Kristina Roxas, Saba Shahin, Oksana Shelest, Soshana Svendsen, Shaomei Wang, and Clive N. Svendsen. Stem Cell Reports, April.

Cancer

Identifying Novel Biomarkers Associated With Bladder Cancer Treatment Outcomes. Castaneda, Peris R., Dan Theodorescu, Charles J. Rosser, and Michael Ahdoot. Frontiers in Oncology 13: 1114203.

Highly Sensitive Noninvasive Early Lung Cancer Detection Using DNA Methylation Topology in Sputum-Derived Epithelial Cells. Soukiasian, Harmik J., Alexander Leung, Taryne Imai, Shika Bose, Sungjin Kim, Zab Mosenifar, Nirdesh K. Gupta, and Jian Tajbakhsh. JTCVS Open 13 (March): 389–410.

The ‘Great Debate’ at Melanoma Bridge 2022, Naples, December 1st-3rd, 2022. Ascierto, Paolo A., Christian Blank, Alexander M. Eggermont, Claus Garbe, Jeffrey E. Gershenwald, Omid Hamid, Axel Hauschild, Jason J. Luke, Janice M. Mehnert, Jeffrey A. Sosman, Hussein A. Tawbi, Mario Mandalà, Alessandro Testori, Corrado Caracò, Iman Osman, and Igor Puzanov. Journal of Translational Medicine 21 (1): 265.

A Scoping Review of Barriers and Facilitators to the Integration of Substance Use Treatment Services into US Mainstream Health Care. Adeniran, Esther, Megan Quinn, Richard Wallace, Rachel R. Walden, Titilola Labisi, Afolakemi Olaniyan, Billy Brooks, and Robert Pack. Drug and Alcohol Dependence Reports 7 (June): 100152.

Cardiac Surgery

Contemporary Outcomes of Mitral Valve Repair for Degenerative Disease in the Era of Increased Penetrance of Percutaneous Mitral Valve Technology. Abt, Brittany G., Michael E. Bowdish, Ramsey S. Elsayed, Robbin Cohen, Markian Bojko, Alexander Vorperian, Michael Brown, and Vaughn A. Starnes. JTCVS Open 13 (March): 106–16.

Multiple Arterial Versus Single Arterial Grafting in Patients With Diabetes Undergoing Coronary Artery Bypass Surgery. Alsaleh, Doaa, Erick Sun, Anas Alzahrani, Shinobu Itagaki, John Puskas, Joanna Chikwe, and Natalia Egorova. JTCVS Open 13 (March): 119–35.

Medicine

Genetic Coding Variant in Complement Factor B (CFB) Is Associated With Increased Risk for Perianal Crohn’s Disease and Leads to Impaired CFB Cleavage and Phagocytosis. Akhlaghpour, Marzieh, Talin Haritunians, Shyam K. More, Lisa S. Thomas, Dalton T. Stamps, Shishir Dube, Dalin Li, Shaohong Yang, Carol J. Landers, Emebet Mengesha, Hussein Hamade, Ramachandran Murali, Alka A. Potdar, Andrea J. Wolf, Gregory J. Botwin, Michelle Khrom, International IBD Genetics Consortium, Ashwin N. Ananthakrishnan, William A. Faubion, Bana Jabri, Sergio A. Lira, Rodney D. Newberry, Robert S. Sandler, R. Balfour Sartor, Ramnik J. Xavier, Steven R. Brant, Judy H. Cho, Richard H. Duerr, Mark G. Lazarev, John D. Rioux, L. Philip Schumm, Mark S. Silverberg, Karen Zaghiyan, Phillip Fleshner, Gil Y. Melmed, Eric A. Vasiliauskas, Christina Ha, Shervin Rabizadeh, Gaurav Syal, Nirupama N. Bonthala, David A. Ziring, Stephan R. Targan, Millie D. Long, Dermot P. B. McGovern, and Kathrin S. Michelsen. Gut, April.

Impact of Sex and Comorbid Diabetes on Hospitalization Outcomes in Acute Pancreatitis: A Large United States Population-Based Study. Weissman, Simcha, Stephen J. Pandol, Umar Ghaffar, Melody Boafo, Chukwuemeka E. Ogbu, Tamer Zahdeh, Mohammed Ashary, Vignesh Krishnan Nagesh, Anushka Kigga, Ayrton Bangolo, and Aditi Bhargava. AIMS Public Health 10 (1): 105–15.