A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators
This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published April 11-18.
Anesthesiology
Use of Herbal Medication in the Perioperative Period: Potential Adverse Drug Interactions. Elvir Lazo, Ofelia Loani, Paul F. White, Carol Lee, Hillenn Cruz Eng, Jenna M. Matin, Cory Lin, Franklin Del Cid, and Roya Yumul. Journal of Clinical Anesthesia 95 (April): 111473.
Biomedical Sciences
Probiotic Lactic Acid Bacteria Promote Anti-Tumor Immunity Through Enhanced Major Histocompatibility Complex Class I-Restricted Antigen Presentation Machinery in Dendritic Cells. Saito, Suguru, Alato Okuno, Zhenzi Peng, Duo-Yao Cao, and Noriko M. Tsuji. Frontiers in Immunology 15: 1335975.
Cortico-Cerebellar Coordination Facilitates Neuroprosthetic Control. Abbasi, Aamir, Rohit Rangwani, Daniel W. Bowen, Andrew W. Fealy, Nathan P. Danielsen, and Tanuj Gulati. Science Advances 10 (15): eadm8246.
Understanding the Implementation and Sustainability Needs of Evidence-Based Programs for Racial and Ethnic Minoritized Older Adults in Under-Resourced Communities With Limited Aging Services. Castellon-Lopez, Yelba, Savanna L. Carson, Katherine T. Ward, Karina D. Ramirez, Lynn Phan Vo, Tony Kuo, Teresa Seeman, Stefanie D. Vassar, Laura Trejo, Ellen Eidem, María P. Aranda, and Arleen F. Brown. BMC Health Services Research 24 (1): 466.
Spatiotemporal Architecture of Immune Cells and Cancer-Associated Fibroblasts in High-Grade Serous Ovarian Carcinoma. Xu, Alexander M., Marcela Haro, Ann E. Walts, Ye Hu, Joshi John, Beth Y. Karlan, Akil Merchant, and Sandra Orsulic. Science Advances 10 (16): eadk8805.
Cardiac Surgery
An Essential Update but are the 2023 Surgical Treatment of Atrial Fibrillation Guidelines Enough? Tam, Derrick Y., and Armin Kiankhooy. The Annals of Thoracic Surgery, April, S0003-4975(24)00283-2.
Response Regarding: Clinical Implication to Predict New-Onset Atrial Fibrillation After Cardiac Surgery. Kataoka N, Imamura T. Bowdish, Michael E., Annetine C. Gelijns, and Emilia Bagiella. The Journal of Surgical Research, April, S0022-4804(24)00097-0.
Cardiology
Comparative Analysis of Treatment Options for Chronic Heart Failure and Depression: A Systematic Review and Bayesian Network Meta-Analysis. Soleimani, Hamidreza, Ali Nasrollahizadeh, Mohsen Hajiqasemi, Mandana Ebrahimzade, Homa Taheri, Pouya Ebrahimi, Haleh Ashraf, Marc D. Samsky, and Kaveh Hosseini. Heart Failure Reviews, April.
Deep Learning Evaluation of Echocardiograms to Identify Occult Atrial Fibrillation. Yuan, Neal, Nathan R. Stein, Grant Duffy, Roopinder K. Sandhu, Sumeet S. Chugh, Peng-Sheng Chen, Carine Rosenberg, Christine M. Albert, Susan Cheng, Robert J. Siegel, and David Ouyang. NPJ Digital Medicine 7 (1): 96.
Prognostic Implication of Right Ventricular Free Wall Longitudinal Strain and Right Atrial Pressure Estimated by Echocardiography in Patients With Severe Functional Tricuspid Regurgitation. Ogawa, Mana, Ken Kuwajima, Takafumi Yamane, Hiroko Hasegawa, Nobuichiro Yagi, and Takahiro Shiota. Journal of the American Heart Association 13 (8): e033196.
Stroke Prevention in Subclinical Atrial Fibrillation. Lee, Todd C., Sanjay Kaul, and John Mandrola. The New England Journal of Medicine 390 (15): 1441.
Imaging
Updates on the Applications of Spectral Computed Tomography for Musculoskeletal Imaging. Eibschutz, Liesl S., George Matcuk, Michael Kuo-Jiun Chiu, Max Yang Lu, and Ali Gholamrezanezhad. Diagnostics (Basel, Switzerland) 14 (7): 732.
American College of Rheumatology (ACR) and Food and Drug Administration (FDA) Summit: Summary of the Meeting May 17-18, 2022. Kay, Jonathan, Nikolay P. Nikolov, Michael H. Weisman, and American College of Rheumatology Committee on Research. Arthritis & Rheumatology (Hoboken, N.J.), April.
Medicine
Ductular Reactions in Liver Injury, Regeneration, and Disease Progression-An Overview. Mavila, Nirmala, Mallikarjuna Siraganahalli Eshwaraiah, and Jaquelene Kennedy. Cells 13 (7): 579.
Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions. Li, Dengxiong, Qingxin Yu, Ruicheng Wu, Zhouting Tuo, Weizhen Zhu, Jie Wang, Fanglin Shao, Luxia Ye, Xing Ye, Koo Han Yoo, Mang Ke, Yubo Yang, Wuran Wei, and Dechao Feng. Aging and Disease, March.
Acromegaly Type 1: A Representative Patient. Cuevas-Ramos, Daniel, and Shlomo Melmed. JCEM Case Reports 2 (4): luae053.
Phase II Study of Erdafitinib in Patients With Tumors With FGFR Amplifications: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol K1. Gong, Jun, Alain C. Mita, Zihan Wei, Heather H. Cheng, Edith P. Mitchell, John J. Wright, S. Percy Ivy, Victoria Wang, Robert C. Gray, Lisa M. McShane, Larry V. Rubinstein, David R. Patton, P. Mickey Williams, Stanley R. Hamilton, Ajjai S. Alva, James V. Tricoli, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O’Dwyer, Alice P. Chen, and Keith T. Flaherty. JCO Precision Oncology 8 (April): e2300406.
Phase II Study of Erdafitinib in Patients With Tumors With Fibroblast Growth Factor Receptor Mutations or Fusions: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol K2. Gong, Jun, Alain C. Mita, Zihan Wei, Heather H. Cheng, Edith P. Mitchell, John J. Wright, S. Percy Ivy, Victoria Wang, Robert C. Gray, Lisa M. McShane, Larry V. Rubinstein, David R. Patton, P. Mickey Williams, Stanley R. Hamilton, James V. Tricoli, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O’Dwyer, Alice P. Chen, and Keith T. Flaherty. JCO Precision Oncology 8 (April): e2300407.
Regorafenib in Patients With Solid Tumors With BRAF Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study. Sahai, Vaibhav, Michael Rothe, Pam K. Mangat, Elizabeth Garrett-Mayer, Vijay Suhag, Elie G. Dib, Inderjit Mehmi, Kunal C. Kadakia, Evan Pisick, Herbert L. Duvivier, Phat Le, Rui Li, David P. Michelin, Ryan E. Wilcox, Gina N. Grantham, Dominique C. Hinshaw, Abigail Gregory, Susan Halabi, and Richard L. Schilsky. JCO Precision Oncology 8 (April): e2300527.
Novel STAT3 Oligonucleotide Compounds Suppress Tumor Growth and Overcome the Acquired Resistance to Sorafenib in Hepatocellular Carcinoma. Zhang, Qi-Yi, Wen Ding, Jian-Shan Mo, Shu-Min Ou-Yang, Zi-You Lin, Ke-Ren Peng, Guo-Pin Liu, Jin-Jian Lu, Pei-Bin Yue, Jin-Ping Lei, Yan-Dong Wang, and Xiao-Lei Zhang. Acta Pharmacologica Sinica, April.
Efficacy and Safety of Etrasimod in Patients With Moderately to Severely Active Isolated Proctitis: Results From the Phase 3 ELEVATE UC Clinical Programme. Peyrin-Biroulet, Laurent, Marla C. Dubinsky, Bruce E. Sands, Julian Panés, Stefan Schreiber, Walter Reinisch, Brian G. Feagan, Silvio Danese, Andres J. Yarur, Geert R. D’Haens, Martina Goetsch, Karolina Wosik, Michael Keating, Krisztina Lazin, Joseph Wu, Irene Modesto, Aoibhinn McDonnell, Lauren Bartolome, and Séverine Vermeire. Journal of Crohn’s & Colitis, April, jjae038.
Detectable Plasma Severe Acute Respiratory Syndrome Coronavirus 2 Spike Antigen Is Associated With Poor Antibody Response Following Third Messenger RNA Vaccination in Kidney Transplant Recipients. Karaba, Andrew H., Zoe Swank, Sarah Hussain, Margaret Chahoud, Christine M. Durand, Dorry L. Segev, Mark A. Robien, Peter S. Heeger, Christian P. Larsen, Aaron A. R. Tobian, David R. Walt, and William A. Werbel. Transplant Infectious Disease, April, e14281.
Functionalization of Niobium Nitrogen-Doped Titanium Dioxide (TiO2) Nanoparticles With Ethanolic Extracts of Mentha Arvensis. Farooqi, Muhammad Awais, Hafiz Muhammad Umer Farooqi, Theophilus Bhatti, Ghayas Uddin Siddiqui, Farzana Kausar, and Chul Ung Kang. Discover Nano 19 (1): 67.
Placental IGFBP1 Levels During Early Pregnancy and the Risk of Insulin Resistance and Gestational Diabetes. Hivert, Marie-France, Frédérique White, Catherine Allard, Kaitlyn James, Sana Majid, François Aguet, Kristin G. Ardlie, Jose C. Florez, Andrea G. Edlow, Luigi Bouchard, Pierre-Étienne Jacques, S. Ananth Karumanchi, and Camille E. Powe. Nature Medicine, April.
Cisd2 Deficiency Impairs Neutrophil Function by Regulating Calcium Homeostasis via Calnexin and SERCA. Choi, Un Yung, Youn Jung Choi, Shin-Ae Lee, and Ji-Seung Yoo. BMB Reports, April, 6179.
Placental Senescence Pathophysiology Is Shared Between Peripartum Cardiomyopathy and Preeclampsia in Mouse and Human. Roh, Jason D., Claire Castro, Andy Yu, Sarosh Rana, Sajid Shahul, Kathryn J. Gray, Michael C. Honigberg, Melanie Ricke-Hoch, Yoshiko Iwamoto, Ashish Yeri, Robert Kitchen, Justin Baldovino Guerra, Ryan Hobson, Vinita Chaudhari, Bliss Chang, Amy Sarma, Carolin Lerchenmüller, Zeina R. Al Sayed, Carmen Diaz Verdugo, Peng Xia, Niv Skarbianskis, Amit Zeisel, Johann Bauersachs, James L. Kirkland, S. Ananth Karumanchi, John Gorcsan, Masataka Sugahara, Julie Damp, Karen Hanley-Yanez, Patrick T. Ellinor, Zoltan Arany, Dennis M. McNamara, IPAC Investigators, Denise Hilfiker-Kleiner, and Anthony Rosenzweig. Science Translational Medicine 16 (743): eadi0077.
Alpha-Fetoprotein: Past, Present, and Future. Yeo, Yee Hui, Yi-Te Lee, Hsian-Rong Tseng, Yazhen Zhu, Sungyong You, Vatche G. Agopian, and Ju Dong Yang. Hepatology Communications 8 (5): e0422.
Neurology
External Validation of the SI2NCAL2C Score for Outcomes Following Cerebral Venous Thrombosis. Klein, Piers, Liqi Shu, Erik Lindgren, Maria A. de Winter, James E. Siegler, Alexis N. Simpkins, Satareh Salehi Omran, Mirjam R. Heldner, Adam de Havenon, Mohamad Abdalkader, Sami Al Kasab, Christoph Stretz, Teddy Y. Wu, Duncan Wilson, Syed Daniyal Asad, Eyad Almallouhi, Jennifer Frontera, Lindsey Kuohn, Aaron Rothstein, Ekaterina Bakradze, Nils Henninger, Adeel S. Zubair, Richa Sharma, Deborah Kerrigan, Yasmin Aziz, Eva A. Mistry, Mayte Sanchez van Kammen, Turgut Tatlisumak, Katarzyna Krzywicka, Diana Aguiar de Sousa, Katarina Jood, Thalia S. Field, Shadi Yaghi, Jonathan M. Coutinho, and Thanh N. Nguyen. Journal of Stroke and Cerebrovascular Diseases, April, 107720.
Neurosurgery
Prefrontal-Subthalamic Theta Signaling Mediates Delayed Responses During Conflict Processing. Choi, Jeong Woo, Mahsa Malekmohammadi, Soroush Niketeghad, Katy A. Cross, Hamasa Ebadi, Amirreza Alijanpourotaghsara, Adam Aron, Ueli Rutishauser, and Nader Pouratian. Progress in Neurobiology, April, 102613.
Functional and Oncological Outcomes After Right Hemisphere Glioma Resection in Awake Versus Asleep Patients: A Systematic Review and Meta-Analysis. Ramírez-Ferrer, Esteban, Maria Paula Aguilera-Pena, and Hugues Duffau. Neurosurgical Review 47 (1): 160.
Control of Working Memory by Phase-Amplitude Coupling of Human Hippocampal Neurons. Daume, Jonathan, Jan Kami?ski, Andrea G. P. Schjetnan, Yousef Salimpour, Umais Khan, Michael Kyzar, Chrystal M. Reed, William S. Anderson, Taufik A. Valiante, Adam N. Mamelak, and Ueli Rutishauser. Nature, April.
Nursing
Development and Testing of the Relational and Structural Components of Innovativeness Across Academia and Practice for Healthcare Progress Scale. Joseph, M. Lindell, Michele Williams, Karl Reinke, Heather Bair, Sena Chae, Kirsten Hanrahan, Barbara St Marie, Peggy Jenkins, Nancy M. Albert, Mary M. Gullatte, Darlene M. Rogers, Beth Ann Swan, Tina Holden, Elizabeth Woods, Pamela B. DeGuzman, Gina DeGennaro, David Marshall, Maria Hein, Yelena Perkhounkova, and Diane L. Huber. The Journal of Nursing Administration, April.
Orthopaedics
Timing of Intraoperative Neurophysiological Monitoring (IONM) Recovery and Clinical Recovery After Termination of Pediatric Spinal Deformity Surgery Due to Loss of IONM Signals. CreveCoeur, Travis S., Rajiv R. Iyer, Hannah E. Goldstein, Mychael W. Delgardo, Todd C. Hankinson, Mark A. Erickson, Sumeet Garg, David L. Skaggs, Lindsay Andras, Benjamin C. Kennedy, Patrick J. Cahill, Lawrence G. Lenke, Peter D. Angevine, Benjamin D. Roye, Michael G. Vitale, Anil Mendiratta, and Richard C. E. Anderson. The Spine Journal, April, S1529-9430(24)00169-4.
Revision of Harrington Rod Constructs: A Single-Center’s Experience With This Homogenous Adult Spinal Deformity Population at a Minimum 2-Year Follow-Up. Stephan, Stephen R., Fthimnir M. Hassan, Christopher Mikhail, Andrew Platt, Erik Lewerenz, Joseph M. Lombardi, Zeeshan M. Sardar, Ronald A. Lehman, and Lawrence G. Lenke. Spine Deformity, April.
Pathology and Laboratory Medicine
Kidney Histopathology of Patients With Hepatitis C Infection and Diabetes Mellitus Before and After Availability of Direct-Acting Antiviral Therapy. Kung, Vanderlene L., Gabriel Giannini, and Cynthia C. Nast. Glomerular Diseases 4 (1): 74–83.
The 1000 Mitoses Project: A Consensus-Based International Collaborative Study on Mitotic Figures Classification. Lin, Sherman, Christopher Tran, Ela Bandari, Tommaso Romagnoli, Yueyang Li, Michael Chu, Abinaya S. Amirthakatesan, Adam Dallmann, Andrii Kostiukov, Angel Panizo, Anjelica Hodgson, Anna R. Laury, Matthew J. Cecchini, et al. International Journal of Surgical Pathology, April, 10668969241234321.
Pediatrics
The Spectrum of Postacute Sequelae of COVID-19 in Children: From MIS-C to Long COVID. Kane, Abigail S., Madeleine Godfrey, Magali Noval Rivas, Moshe Arditi, Alessio Fasano, and Lael M. Yonker. Annual Review of Virology, April.
Physical Medicine & Rehabilitation
Using Electronic Health Record Data for Occupational Therapy Health Services Research: Invited Commentary. Cogan, Alison M., Pamela Roberts, and Trudy Mallinson. OTJR: Occupation, Participation and Health, April, 15394492241246544.
Surgery
Comparison of Clinical Breast Exam to Breast MRI Surveillance in Patients Following Nipple-Sparing Mastectomy. Weed, Christina, Ton Wang, Srivarshini C. Mohan, Xuanji Wang, Joshua Tseng, Theodore Hu, Jutla Jaswinder, Marissa K. Boyle, Farin Amersi, Armando Giuliano, and Alice Chung. Clinical Breast Cancer, March, S1526-8209(24)00097-1.
Differential RNA Expression Between Metastatic and Primary Neuroblastoma Cells. Lee, William G., Grace E. Asuelime, Matthew B. T. Asuelime-Smith, Stephanie Y. Chen, and Eugene S. Kim. The Journal of Surgical Research 298 (April): 240–50.
Urology
Addressing Racial Disparities in Prostate Cancer Pathology Prediction Models: External Validation and Comparison of Four Models of Pathological Outcome Prediction Before Radical Prostatectomy in the Multiethnic SEARCH Cohort. Mottaghi, Mahdi, Lin Gu, Sriram Deivasigamani, Eric S. Adams, Joshua Parrish, Christopher L. Amling, William J. Aronson, Christopher J. Kane, Martha K. Terris, Lourdes Guerrios-Rivera, Matthew R. Cooperberg, Zachary Klaassen, Stephen J. Freedland, and Thomas J. Polascik. Prostate Cancer and Prostatic Diseases, April.